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The Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent

PLoS pathogens, 2016-08, Vol.12 (8), p.e1005809-e1005809

2016

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The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection

PLoS pathogens, 2018-12, Vol.14 (12), p.e1007501-e1007501

2018

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Mycobacterium abscessus infection leads to enhanced production of type 1 interferon and NLRP3 inflammasome activation in murine macrophages via mitochondrial oxidative stress

PLoS pathogens, 2020-03, Vol.16 (3), p.e1008294-e1008294

2020

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PPARγ is critical for Mycobacterium tuberculosis induction of Mcl-1 and limitation of human macrophage apoptosis

PLoS pathogens, 2018-06, Vol.14 (6), p.e1007100-e1007100

2018

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Activation of transcription factor CREB in human macrophages by Mycobacterium tuberculosis promotes bacterial survival, reduces NF-kB nuclear transit and limits phagolysosome fusion by reduced necroptotic signaling

PLoS pathogens, 2023-03, Vol.19 (3), p.e1011297-e1011297

2023

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Allele-specific induction of IL-1β expression by C/EBPβ and PU.1 contributes to increased tuberculosis susceptibility

PLoS pathogens, 2014-10, Vol.10 (10), p.e1004426-e1004426

2014

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A nod to the bond between NOD2 and mycobacteria

PLoS pathogens, 2023-06, Vol.19 (6), p.e1011389

2023

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The ESX-4 substrates, EsxU and EsxT, modulate Mycobacterium abscessus fitness

PLoS pathogens, 2022-08, Vol.18 (8), p.e1010771-e1010771

2022

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TNF-α antagonists differentially induce TGF-β1-dependent resuscitation of dormant-like Mycobacterium tuberculosis

PLoS pathogens, 2020-02, Vol.16 (2), p.e1008312-e1008312

2020

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Allele-dependent interaction of LRRK2 and NOD2 in leprosy

PLoS pathogens, 2023-03, Vol.19 (3), p.e1011260-e1011260

2023

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The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions

PLoS pathogens, 2020-08, Vol.16 (8), p.e1008818-e1008818

2020

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Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways

PLoS pathogens, 2017-09, Vol.13 (9), p.e1006577-e1006577

2017

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Antibody to Poly-N-acetyl glucosamine provides protection against intracellular pathogens: Mechanism of action and validation in horse foals challenged with Rhodococcus equi

PLoS pathogens, 2018-07, Vol.14 (7), p.e1007160-e1007160

2018

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Type-I interferons promote innate immune tolerance in macrophages exposed to Mycobacterium ulcerans vesicles

PLoS pathogens, 2023-07, Vol.19 (7), p.e1011479-e1011479

2023

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Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1β, are linked to fibrin formation in Buruli ulcer lesions

PLoS pathogens, 2022-01, Vol.18 (1), p.e1010280-e1010280

2022

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Host cytosolic RNA sensing pathway promotes T Lymphocyte-mediated mycobacterial killing in macrophages

PLoS pathogens, 2020-05, Vol.16 (5), p.e1008569-e1008569

2020

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Family-based genome-wide association study of leprosy in Vietnam

PLoS pathogens, 2020-05, Vol.16 (5), p.e1008565-e1008565

2020

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The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferon by engaging cytosolic DNA sensing in macrophages

PLoS pathogens, 2021-09, Vol.17 (9), p.e1009888-e1009888

2021

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Ethnic variation in inflammatory profile in tuberculosis

PLoS pathogens, 2013-07, Vol.9 (7), p.e1003468

2013

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Within Host Evolution Selects for a Dominant Genotype of Mycobacterium tuberculosis while T Cells Increase Pathogen Genetic Diversity

PLoS pathogens, 2016-12, Vol.12 (12), p.e1006111

2016

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Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection

Nature reviews. Immunology, 2018-09, Vol.18 (9), p.575-589

2018

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Clinical Development of New TB Vaccines: Recent Advances and Next Steps

Frontiers in microbiology, 2020-01, Vol.10, p.3154-3154

2020

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Toll-like receptor polymorphisms and susceptibility to human disease

Clinical science (1979), 2008-03, Vol.114 (5), p.347-360

2008

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Host-Directed Therapeutics for Tuberculosis: Can We Harness the Host?

Microbiology and Molecular Biology Reviews, 2013-12, Vol.77 (4), p.608-627

2013

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The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans

Cell, 2010-03, Vol.140 (5), p.717-730

2010

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The Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent

The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection

Mycobacterium abscessus infection leads to enhanced production of type 1 interferon and NLRP3 inflammasome activation in murine macrophages via mitochondrial oxidative stress

PPARγ is critical for Mycobacterium tuberculosis induction of Mcl-1 and limitation of human macrophage apoptosis

Activation of transcription factor CREB in human macrophages by Mycobacterium tuberculosis promotes bacterial survival, reduces NF-kB nuclear transit and limits phagolysosome fusion by reduced necroptotic signaling

Allele-specific induction of IL-1β expression by C/EBPβ and PU.1 contributes to increased tuberculosis susceptibility

A nod to the bond between NOD2 and mycobacteria

The ESX-4 substrates, EsxU and EsxT, modulate Mycobacterium abscessus fitness

TNF-α antagonists differentially induce TGF-β1-dependent resuscitation of dormant-like Mycobacterium tuberculosis

Allele-dependent interaction of LRRK2 and NOD2 in leprosy

The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions

Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways

Antibody to Poly-N-acetyl glucosamine provides protection against intracellular pathogens: Mechanism of action and validation in horse foals challenged with Rhodococcus equi

Type-I interferons promote innate immune tolerance in macrophages exposed to Mycobacterium ulcerans vesicles

Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1β, are linked to fibrin formation in Buruli ulcer lesions

Host cytosolic RNA sensing pathway promotes T Lymphocyte-mediated mycobacterial killing in macrophages

Family-based genome-wide association study of leprosy in Vietnam

The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferon by engaging cytosolic DNA sensing in macrophages

Ethnic variation in inflammatory profile in tuberculosis

Within Host Evolution Selects for a Dominant Genotype of Mycobacterium tuberculosis while T Cells Increase Pathogen Genetic Diversity

Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection

Clinical Development of New TB Vaccines: Recent Advances and Next Steps

Toll-like receptor polymorphisms and susceptibility to human disease

Host-Directed Therapeutics for Tuberculosis: Can We Harness the Host?

The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans

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