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AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

Cell metabolism, 2013-10, Vol.18 (4), p.556-566

2013

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Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

Nature (London), 2017-08, Vol.548 (7665), p.112-116

2017

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The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

Diabetes (New York, N.Y.), 2016-09, Vol.65 (9), p.2784-2794

2016

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The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

Science (American Association for the Advancement of Science), 2012-05, Vol.336 (6083), p.918-922

2012

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Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells

Biochemical journal, 2014-04, Vol.459 (2), p.275-287

2014

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AMP-activated protein kinase â development of the energy sensor concept

The Journal of physiology, 2006-07, Vol.574 (1), p.7-15

2006

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Mechanism of Activation of AMPK by Cordycepin

Cell chemical biology, 2020-02, Vol.27 (2), p.214-222.e4

2020

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Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress

Cell research, 2019-06, Vol.29 (6), p.460-473

2019

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BAY-3827 and SBI-0206965: Potent AMPK Inhibitors That Paradoxically Increase Thr172 Phosphorylation

International journal of molecular sciences, 2023-12, Vol.25 (1), p.453

2023

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Mechanism of Action of A-769662, a Valuable Tool for Activation of AMP-activated Protein Kinase

The Journal of biological chemistry, 2007-11, Vol.282 (45), p.32549-32560

2007

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Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib

Cell chemical biology, 2017-07, Vol.24 (7), p.813-824.e4

2017

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Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling

Science signaling, 2016-11, Vol.9 (453), p.ra109

2016

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Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP

Biochemical journal, 2010-01, Vol.426 (1), p.109-118

2010

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Aging-Associated Reductions in AMP-Activated Protein Kinase Activity and Mitochondrial Biogenesis

Cell metabolism, 2007-02, Vol.5 (2), p.151-156

2007

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Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation

Diabetes (New York, N.Y.), 2015-02, Vol.64 (2), p.360-369

2015

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Caspase cleavage and nuclear retention of the energy sensor AMPK-α1 during apoptosis

Cell reports (Cambridge), 2022-05, Vol.39 (5), p.110761-110761, Article 110761

2022

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AMPK: a nutrient and energy sensor that maintains energy homeostasis

Nature reviews. Molecular cell biology, 2012-04, Vol.13 (4), p.251

2012

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The Antidiabetic Drug Metformin Activates the AMP-Activated Protein Kinase Cascade via an Adenine Nucleotide-Independent Mechanism

Diabetes (New York, N.Y.), 2002-08, Vol.51 (8), p.2420-2425

2002

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Cannabinoids and Ghrelin Have Both Central and Peripheral Metabolic and Cardiac Effects via AMP-activated Protein Kinase

The Journal of biological chemistry, 2005-07, Vol.280 (26), p.25196-25201

2005

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A Novel Domain in AMP-Activated Protein Kinase Causes Glycogen Storage Bodies Similar to Those Seen in Hereditary Cardiac Arrhythmias

Current biology, 2003-05, Vol.13 (10), p.861-866

2003

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Elm1p Is One of Three Upstream Kinases for the Saccharomyces cerevisiae SNF1 Complex

Current biology, 2003-08, Vol.13 (15), p.1299-1305

2003

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Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

Journal of biology (London, England), 2003, Vol.2 (4), p.28-28

2003

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A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis

Biochemical journal, 2008-11, Vol.416 (1), p.1-14

2008

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AMP-activated protein kinase can be allosterically activated by ADP but AMP remains the key activating ligand

Biochemical journal, 2024-04, Vol.481 (8), p.587-599

2024

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Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers

Biochemical journal, 2023-12, Vol.480 (23), p.1951-1968

2023

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AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells

AMP-activated protein kinase â development of the energy sensor concept

Mechanism of Activation of AMPK by Cordycepin

Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress

BAY-3827 and SBI-0206965: Potent AMPK Inhibitors That Paradoxically Increase Thr172 Phosphorylation

Mechanism of Action of A-769662, a Valuable Tool for Activation of AMP-activated Protein Kinase

Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib

Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling

Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP

Aging-Associated Reductions in AMP-Activated Protein Kinase Activity and Mitochondrial Biogenesis

Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation

Caspase cleavage and nuclear retention of the energy sensor AMPK-α1 during apoptosis

AMPK: a nutrient and energy sensor that maintains energy homeostasis

The Antidiabetic Drug Metformin Activates the AMP-Activated Protein Kinase Cascade via an Adenine Nucleotide-Independent Mechanism

Cannabinoids and Ghrelin Have Both Central and Peripheral Metabolic and Cardiac Effects via AMP-activated Protein Kinase

A Novel Domain in AMP-Activated Protein Kinase Causes Glycogen Storage Bodies Similar to Those Seen in Hereditary Cardiac Arrhythmias

Elm1p Is One of Three Upstream Kinases for the Saccharomyces cerevisiae SNF1 Complex

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis

AMP-activated protein kinase can be allosterically activated by ADP but AMP remains the key activating ligand

Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers

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