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A suite of PCR-LwCas13a assays for detection and genotyping of Treponema pallidum in clinical samples

Nature communications, 2022-08, Vol.13 (1), p.4671-4671, Article 4671

2022

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Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis

PLoS pathogens, 2020-09, Vol.16 (9), p.e1008871-e1008871

2020

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The RpoS Gatekeeper in Borrelia burgdorferi : An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity

Frontiers in microbiology, 2019-08, Vol.10, p.1923-1923

2019

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Analysis of Treponema pallidum Strains From China Using Improved Methods for Whole-Genome Sequencing From Primary Syphilis Chancres

The Journal of infectious diseases, 2021-03, Vol.223 (5), p.848-853

2021

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Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326)

Frontiers in immunology, 2023-08, Vol.14, p.1222267

2023

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Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation

BMC immunology, 2021-05, Vol.22 (1), p.32-32, Article 32

2021

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Extracellular Loops of the Treponema pallidum FadL Orthologs TP0856 and TP0858 Elicit IgG Antibodies and IgG + -Specific B-Cells in the Rabbit Model of Experimental Syphilis

mBio, 2022-08, Vol.13 (4), p.e0163922

2022

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IFNγ Enhances CD64-Potentiated Phagocytosis of Treponema pallidum Opsonized with Human Syphilitic Serum by Human Macrophages

Frontiers in immunology, 2017-10, Vol.8, p.1227-1227

2017

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CD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferi

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (4), p.1228-1232

2012

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FcεRI cross-linking reduces cord blood dendritic cell responsiveness to LPS

Journal of allergy and clinical immunology, 2017-06, Vol.139 (6), p.1992-1994.e3

2017

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Controlled M1-to-M2 transition of aged macrophages by calcium phosphate coatings

Biomaterials, 2019-03, Vol.196, p.90-99

2019

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Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine

Journal of bacteriology, 2021-07, Vol.203 (15), p.e0008221-e0008221

2021

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New Pathways in Syphilis Vaccine Development

Sexually transmitted diseases, 2024-07

2024

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Treponema pallidum Periplasmic and Membrane Proteins Are Recognized by Circulating and Skin CD4+ T Cells

The Journal of infectious diseases, 2024-08, Vol.230 (2), p.281-292

2024

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Clinical Presentation of Early Syphilis and Genomic Sequences of Treponema pallidum Strains in Patient Specimens and Isolates Obtained by Rabbit Inoculation

The Journal of infectious diseases, 2024-06

2024

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Sequence Variation of Rare Outer Membrane Protein β-Barrel Domains in Clinical Strains Provides Insights into the Evolution of Treponema pallidum subsp. pallidum , the Syphilis Spirochete

mBio, 2018-06, Vol.9 (3)

2018

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Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326

Journal of bacteriology, 2015-06, Vol.197 (11), p.1906-1920

2015

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Clinical and genomic diversity of Treponema pallidum subspecies pallidum to inform vaccine research: an international, molecular epidemiology study

The Lancet. Microbe, 2024-09, Vol.5 (9), p.100871-None, Article 100871

2024

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Serum C3 Enhances Complement Receptor 3-Mediated Phagocytosis of Borrelia burgdorferi

International journal of biological sciences, 2015-01, Vol.11 (11), p.1269-1271

2015

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Phagosomal TLR signaling upon Borrelia burgdorferi infection

Frontiers in cellular and infection microbiology, 2014, Vol.4, p.55-55

2014

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CD14 targets complement receptor 3 to lipid rafts during phagocytosis of Borrelia burgdorferi

International journal of biological sciences, 2013-01, Vol.9 (8), p.803-810

2013

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Inflammation and immune evasion coexist in Treponema pallidum–infected skin

JAAD Case Reports, 2018-06, Vol.4 (5), p.462-464

2018

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Fc[epsilon]RI cross-linking reduces cord blood dendritic cell responsiveness to LPS

Journal of allergy and clinical immunology, 2017-06, Vol.139 (6), p.1992

2017

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High-throughput nanopore sequencing of Treponema pallidum tandem repeat genes arp and tp0470 reveals clade-specific patterns and recapitulates global whole genome phylogeny

Frontiers in microbiology, 2022-09, Vol.13, p.1007056

2022

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A suite of PCR-LwCas13a assays for detection and genotyping of Treponema pallidum in clinical samples

Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis

The RpoS Gatekeeper in Borrelia burgdorferi : An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity

Analysis of Treponema pallidum Strains From China Using Improved Methods for Whole-Genome Sequencing From Primary Syphilis Chancres

Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326)

Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation

Extracellular Loops of the Treponema pallidum FadL Orthologs TP0856 and TP0858 Elicit IgG Antibodies and IgG + -Specific B-Cells in the Rabbit Model of Experimental Syphilis

IFNγ Enhances CD64-Potentiated Phagocytosis of Treponema pallidum Opsonized with Human Syphilitic Serum by Human Macrophages

CD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferi

FcεRI cross-linking reduces cord blood dendritic cell responsiveness to LPS

Controlled M1-to-M2 transition of aged macrophages by calcium phosphate coatings

Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine

New Pathways in Syphilis Vaccine Development

Treponema pallidum Periplasmic and Membrane Proteins Are Recognized by Circulating and Skin CD4+ T Cells

Clinical Presentation of Early Syphilis and Genomic Sequences of Treponema pallidum Strains in Patient Specimens and Isolates Obtained by Rabbit Inoculation

Treponema pallidum genetic diversity and its implications for targeted vaccine development: A cross-sectional study of early syphilis cases in Southwestern Colombia

Sequence Variation of Rare Outer Membrane Protein β-Barrel Domains in Clinical Strains Provides Insights into the Evolution of Treponema pallidum subsp. pallidum , the Syphilis Spirochete

Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326

Clinical and genomic diversity of Treponema pallidum subspecies pallidum to inform vaccine research: an international, molecular epidemiology study

Serum C3 Enhances Complement Receptor 3-Mediated Phagocytosis of Borrelia burgdorferi

Phagosomal TLR signaling upon Borrelia burgdorferi infection

CD14 targets complement receptor 3 to lipid rafts during phagocytosis of Borrelia burgdorferi

Inflammation and immune evasion coexist in Treponema pallidum–infected skin

Fc[epsilon]RI cross-linking reduces cord blood dendritic cell responsiveness to LPS

High-throughput nanopore sequencing of Treponema pallidum tandem repeat genes arp and tp0470 reveals clade-specific patterns and recapitulates global whole genome phylogeny

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