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Recent and Ongoing Research into Metastatic Osteosarcoma Treatments

International journal of molecular sciences, 2022-03, Vol.23 (7), p.3817

2022

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Reconstitution of human pyroptotic cell death in Saccharomyces cerevisiae

Scientific reports, 2023-02, Vol.13 (1), p.3095-3095, Article 3095

2023

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Mutagenic Consequences of Sublethal Cell Death Signaling

International journal of molecular sciences, 2021-06, Vol.22 (11), p.6144

2021

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CrmA orthologs from diverse poxviruses potently inhibit caspases-1 and -8, yet cleavage site mutagenesis frequently produces caspase-1-specific variants

Biochemical journal, 2019-05, Vol.476 (9), p.1335-1357

2019

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Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly

Cell reports (Cambridge), 2019-11, Vol.29 (7), p.1821-1831.e3

2019

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Smac mimetics LCL161 and GDC-0152 inhibit osteosarcoma growth and metastasis in mice

BMC cancer, 2019-09, Vol.19 (1), p.924-18, Article 924

2019

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Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (47), p.18081-18087

2008

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Mammalian initiator apoptotic caspases

The FEBS journal, 2005-11, Vol.272 (21), p.5436-5453

2005

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SfDronc, an initiator caspase involved in apoptosis in the fall armyworm Spodoptera frugiperda

Insect biochemistry and molecular biology, 2013-05, Vol.43 (5), p.444-454

2013

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The Drosophila Caspase Inhibitor DIAP1 Is Essential for Cell Survival and Is Negatively Regulated by HID

Cell, 1999-08, Vol.98 (4), p.453-463

1999

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Hsp72 Inhibits Apoptosis Upstream of the Mitochondria and Not through Interactions with Apaf-1

The Journal of biological chemistry, 2004-12, Vol.279 (49), p.51490-51499

2004

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Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine

Cell death & disease, 2017-10, Vol.8 (10), p.e3062-e3062

2017

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Mature DIABLO/Smac is produced by the IMP protease complex on the mitochondrial inner membrane

Molecular biology of the cell, 2005-06, Vol.16 (6), p.2926-2933

2005

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Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function

The Journal of biological chemistry, 2008-07, Vol.283 (28), p.19499-19510

2008

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DIABLO Promotes Apoptosis by Removing MIHA/XIAP from Processed Caspase 9

The Journal of cell biology, 2001-02, Vol.152 (3), p.483-490

2001

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Analysis of the minimal specificity of caspase-2 and identification of Ac-VDTTD-AFC as a caspase-2-selective peptide substrate

Bioscience reports, 2014-04, Vol.34 (2)

2014

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Establishment and Characterisation of Metastatic Extraskeletal Ewing Sarcoma Mouse Models

In vivo (Athens), 2021-11, Vol.35 (6), p.3097-3106

2021

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Mutagenic assessment of chemotherapy and Smac mimetic drugs in cells with defective DNA damage response pathways

Scientific reports, 2018-09, Vol.8 (1), p.14421-14, Article 14421

2018

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Vaccinia Virus Encodes a Novel Inhibitor of Apoptosis That Associates with the Apoptosome

Journal of virology, 2017-12, Vol.91 (23)

2017

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Caspase inhibitors of the P35 family are more active when purified from yeast than bacteria

PloS one, 2012-06, Vol.7 (6), p.e39248-e39248

2012

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The smac mimetic LCL161 targets established pulmonary osteosarcoma metastases in mice

Clinical & experimental metastasis, 2021-10, Vol.38 (5), p.441-449

2021

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In vitro analysis reveals necroptotic signaling does not provoke DNA damage or HPRT mutations

Cell death & disease, 2020-08, Vol.11 (8), p.680, Article 680

2020

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Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2

Nature structural & molecular biology, 2023-09, Vol.30 (9), p.1265-1274

2023

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Proteasome inhibitors trigger mutations via activation of caspases and CAD, but mutagenesis provoked by the HDAC inhibitors vorinostat and romidepsin is caspase/CAD-independent

Apoptosis (London), 2019-06, Vol.24 (5-6), p.404-413

2019

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cloning method to identify caspases and their regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1

Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (6), p.2885-2890

1999

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Recent and Ongoing Research into Metastatic Osteosarcoma Treatments

Reconstitution of human pyroptotic cell death in Saccharomyces cerevisiae

Mutagenic Consequences of Sublethal Cell Death Signaling

CrmA orthologs from diverse poxviruses potently inhibit caspases-1 and -8, yet cleavage site mutagenesis frequently produces caspase-1-specific variants

Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly

Smac mimetics LCL161 and GDC-0152 inhibit osteosarcoma growth and metastasis in mice

Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax

Mammalian initiator apoptotic caspases

SfDronc, an initiator caspase involved in apoptosis in the fall armyworm Spodoptera frugiperda

The Drosophila Caspase Inhibitor DIAP1 Is Essential for Cell Survival and Is Negatively Regulated by HID

Hsp72 Inhibits Apoptosis Upstream of the Mitochondria and Not through Interactions with Apaf-1

Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine

Mature DIABLO/Smac is produced by the IMP protease complex on the mitochondrial inner membrane

Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function

DIABLO Promotes Apoptosis by Removing MIHA/XIAP from Processed Caspase 9

Analysis of the minimal specificity of caspase-2 and identification of Ac-VDTTD-AFC as a caspase-2-selective peptide substrate

Establishment and Characterisation of Metastatic Extraskeletal Ewing Sarcoma Mouse Models

Mutagenic assessment of chemotherapy and Smac mimetic drugs in cells with defective DNA damage response pathways

Vaccinia Virus Encodes a Novel Inhibitor of Apoptosis That Associates with the Apoptosome

Caspase inhibitors of the P35 family are more active when purified from yeast than bacteria

The smac mimetic LCL161 targets established pulmonary osteosarcoma metastases in mice

In vitro analysis reveals necroptotic signaling does not provoke DNA damage or HPRT mutations

Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2

Proteasome inhibitors trigger mutations via activation of caspases and CAD, but mutagenesis provoked by the HDAC inhibitors vorinostat and romidepsin is caspase/CAD-independent

cloning method to identify caspases and their regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1

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