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3,5,7-Substituted Pyrazolo[4,3‑d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders

Journal of medicinal chemistry, 2022-07, Vol.65 (13), p.8881-8896

2022

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Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7

Biomedicine & pharmacotherapy, 2023-05, Vol.161, p.114492-114492, Article 114492

2023

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Sulfation of Phenolic Acids: Chemoenzymatic vs. Chemical Synthesis

International journal of molecular sciences, 2022-12, Vol.23 (23), p.15171

2022

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Diphenylurea-derived cytokinin oxidase/dehydrogenase inhibitors for biotechnology and agriculture

Journal of experimental botany, 2021-02, Vol.72 (2), p.355-370

2021

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3,5,7-Substituted Pyrazolo[4,3‑d]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models

Journal of medicinal chemistry, 2019-05, Vol.62 (9), p.4606-4623

2019

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5-Substituted 3-isopropyl-7-[4-(2-pyridyl)benzyl]amino-1(2)H-pyrazolo[4,3-d]pyrimidines with anti-proliferative activity as potent and selective inhibitors of cyclin-dependent kinases

European journal of medicinal chemistry, 2016-03, Vol.110, p.291-301

2016

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Polyamine derivatives of betulinic acid and β-sitosterol: A comparative investigation

Steroids, 2015-08, Vol.100, p.27-35

2015

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Cytoprotective activities of kinetin purine isosteres

Bioorganic & medicinal chemistry, 2021-03, Vol.33, p.115993-115993, Article 115993

2021

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Immunoaffinity chromatography of abscisic acid combined with electrospray liquid chromatography–mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007-03, Vol.847 (2), p.162-173

2007

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Amphiphilic derivatives of (3β,17β)-3-hydroxyandrost-5-ene-17-carboxylic acid

Steroids, 2017-12, Vol.128, p.58-67

2017

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2,6,9-Trisubstituted purines as CRK3 kinase inhibitors with antileishmanial activity in vitro

Bioorganic & medicinal chemistry letters, 2015-06, Vol.25 (11), p.2298-2301

2015

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Characterization of a Pyrazolo[4,3-d]pyrimidine Inhibitor of Cyclin-Dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity In Vitro

Chemical biology & drug design, 2015-12, Vol.86 (6), p.1528-1540

2015

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The Identification of a Novel Highly Condensed Pentacyclic Heteroaromatic Ring System 1,3,5,5b,6,8,10,10b-Octaazacyclopenta[h,i]Aceanthrylene and its Application in the Synthesis of 5,7-Substituted Pyrazolo[4,3-d]Pyrimidines

Journal of heterocyclic chemistry, 2015-05, Vol.52 (3), p.669-673

2015

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Prokaryotic and Eukaryotic Aryl Sulfotransferases: Sulfation of Quercetin and Its Derivatives

ChemCatChem, 2015-10, Vol.7 (19), p.3152-3162

2015

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Amides derived from heteroaromatic amines and selected steryl hemiesters

Steroids, 2013-12, Vol.78 (14), p.1347-1352

2013

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Anti-leishmanial activity of disubstituted purines and related pyrazolo[4,3- d]pyrimidines

Bioorganic & medicinal chemistry letters, 2011-07, Vol.21 (14), p.4233-4237

2011

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A Novel Roscovitine Derivative Potently Induces G1-Phase Arrest in Platelet-Derived Growth Factor-BB-Activated Vascular Smooth Muscle Cells

Molecular pharmacology, 2010-02, Vol.77 (2), p.255-261

2010

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Anti-angiogenic effects of purine inhibitors of cyclin dependent kinases

Angiogenesis (London), 2011-09, Vol.14 (3), p.281-291

2011

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Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity

Journal of medicinal chemistry, 2011-04, Vol.54 (8), p.2980-2993

2011

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Trisubstituted purines are useful tools for developing potent plant mitogen-activated protein kinase inhibitors

Bioscience, biotechnology, and biochemistry, 2010, Vol.74 (3), p.553-557

2010

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Trisubstituted pyrazolopyrimidines as novel angiogenesis inhibitors

PloS one, 2013-01, Vol.8 (1), p.e54607

2013

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Novel potent inhibitors of A. thaliana cytokinin oxidase/dehydrogenase

Bioorganic & medicinal chemistry, 2008-10, Vol.16 (20), p.9268-9275

2008

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Synthesis and biological activity of olomoucine II

Bioorganic & medicinal chemistry letters, 2002-11, Vol.12 (22), p.3283-3286

2002

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Occurrence of Two 5-Aminolevulinate Biosynthetic Pathways in Streptomyces nodosus subsp. asukaensis Is Linked with the Production of Asukamycin

Journal of Bacteriology, 2006-07, Vol.188 (14), p.5113-5123

2006

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Inverted Pendulum Optimal Control Based on First Principle Model

Automation Control Theory Perspectives in Intelligent Systems, p.63-74

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3,5,7-Substituted Pyrazolo[4,3‑d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders

Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7

Sulfation of Phenolic Acids: Chemoenzymatic vs. Chemical Synthesis

Diphenylurea-derived cytokinin oxidase/dehydrogenase inhibitors for biotechnology and agriculture

3,5,7-Substituted Pyrazolo[4,3‑d]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models

5-Substituted 3-isopropyl-7-[4-(2-pyridyl)benzyl]amino-1(2)H-pyrazolo[4,3-d]pyrimidines with anti-proliferative activity as potent and selective inhibitors of cyclin-dependent kinases

Polyamine derivatives of betulinic acid and β-sitosterol: A comparative investigation

Cytoprotective activities of kinetin purine isosteres

Immunoaffinity chromatography of abscisic acid combined with electrospray liquid chromatography–mass spectrometry

Amphiphilic derivatives of (3β,17β)-3-hydroxyandrost-5-ene-17-carboxylic acid

2,6,9-Trisubstituted purines as CRK3 kinase inhibitors with antileishmanial activity in vitro

Characterization of a Pyrazolo[4,3-d]pyrimidine Inhibitor of Cyclin-Dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity In Vitro

The Identification of a Novel Highly Condensed Pentacyclic Heteroaromatic Ring System 1,3,5,5b,6,8,10,10b-Octaazacyclopenta[h,i]Aceanthrylene and its Application in the Synthesis of 5,7-Substituted Pyrazolo[4,3-d]Pyrimidines

Prokaryotic and Eukaryotic Aryl Sulfotransferases: Sulfation of Quercetin and Its Derivatives

Amides derived from heteroaromatic amines and selected steryl hemiesters

Anti-leishmanial activity of disubstituted purines and related pyrazolo[4,3- d]pyrimidines

A Novel Roscovitine Derivative Potently Induces G1-Phase Arrest in Platelet-Derived Growth Factor-BB-Activated Vascular Smooth Muscle Cells

Anti-angiogenic effects of purine inhibitors of cyclin dependent kinases

Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity

Trisubstituted purines are useful tools for developing potent plant mitogen-activated protein kinase inhibitors

Trisubstituted pyrazolopyrimidines as novel angiogenesis inhibitors

Novel potent inhibitors of A. thaliana cytokinin oxidase/dehydrogenase

Synthesis and biological activity of olomoucine II

Occurrence of Two 5-Aminolevulinate Biosynthetic Pathways in Streptomyces nodosus subsp. asukaensis Is Linked with the Production of Asukamycin

Inverted Pendulum Optimal Control Based on First Principle Model

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