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In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit

Antiviral research, 2018-12, Vol.160, p.109-117

2018

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Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively

Scientific reports, 2015-01, Vol.5 (1), p.8042-8042, Article 8042

2015

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Dolutegravir interactions with HIV-1 integrase-DNA: structural rationale for drug resistance and dissociation kinetics

PloS one, 2013-10, Vol.8 (10), p.e77448

2013

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Predicting Key Example Compounds in Competitors' Patent Applications Using Structural Information Alone

Journal of chemical information and modeling, 2008-01, Vol.48 (1), p.135-142

2008

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Synthesis and SAR Study of Carbamoyl Pyridone Bicycle Derivatives as Potent Inhibitors of Influenza Cap-dependent Endonuclease

Journal of medicinal chemistry, 2019-09, Vol.62 (17), p.8101-8114

2019

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Discovery of novel cyclic peptide inhibitors of dengue virus NS2B-NS3 protease with antiviral activity

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (15), p.3586-3590

2017

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Effects of Rate and Timing of Fertilizer Application on Yield of Macadamia (Macadamia integrifolia Maiden & Betche) in Japan

Tropical Agriculture and Development, 2012, Vol.56(1), pp.9-13

2012

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Effect of Girdling Treatment on Number of Flowers in Japanese Pepper ‘Budousanshou’ Grafted on Vigorous Rootstock ‘Karasuzanshou’

Tropical Agriculture and Development, 2011, Vol.55(3), pp.118-121

2011

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Conformational Restriction Approach to β‑Secretase (BACE1) Inhibitors: Effect of a Cyclopropane Ring To Induce an Alternative Binding Mode

Journal of medicinal chemistry, 2012-10, Vol.55 (20), p.8838-8858

2012

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Discovery of novel 5-hydroxy-4-pyridone-3-carboxy acids as potent inhibitors of influenza Cap-dependent endonuclease

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (19), p.4739-4742

2016

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Conformational restriction approach to β-secretase (BACE1) inhibitors III: Effective investigation of the binding mode by combinational use of X-ray analysis, isothermal titration calorimetry and theoretical calculations

Bioorganic & medicinal chemistry, 2013-11, Vol.21 (21), p.6506-6522

2013

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Conformational restriction approach to BACE1 inhibitors II: SAR study of the isocytosine derivatives fixed with a cis-cyclopropane ring

Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (10), p.2912-2915

2013

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Predicting human liver microsomal stability with machine learning techniques

Journal of molecular graphics & modelling, 2008-02, Vol.26 (6), p.907-915

2008

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Conformational restriction approach to I2-secretase (BACE1) inhibitors III: Effective investigation of the binding mode by combinational use of X-ray analysis, isothermal titration calorimetry and theoretical calculations

Bioorganic & medicinal chemistry, 2013-11, Vol.21 (21), p.6506-6522

2013

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Molting hormonal and larvicidal activities of aliphatic acyl analogs of dibenzoylhydrazine insecticides

Steroids, 1997-10, Vol.62 (10), p.638-642

1997

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Quantitative structure-activity studies of insect growth regulators xiv. Three-dimensional quantitative structure-activity relationship of ecdysone agonists including dibenzoylhydrazine analogs

Pesticide science, 1998-08, Vol.53 (4), p.267-277

1998

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Discovery of novel and orally active NR2B-selective N-methyl- d-aspartate (NMDA) antagonists, pyridinol derivatives with reduced HERG binding affinity

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (20), p.5533-5536

2007

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Discovery of (−)-6-[2-[4-(3-fluorophenyl)-4-hydroxy-1-piperidinyl]-1-hydroxyethyl]-3,4-dihydro-2(1 H)-quinolinone—A potent NR2B-selective N-methyl d-aspartate (NMDA) antagonist for the treatment of pain

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (20), p.5558-5562

2007

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Dolutegravir Interactions with HIV-1 Integrase-DNA: Structural Rationale for Drug Resistance and Dissociation Kinetics: e77448

PloS one, 2013-10, Vol.8 (10)

2013

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Solid-state characterization of an NR2B selective N-methyl d-aspartate (NMDA) antagonist polymorphs

International journal of pharmaceutics, 2008-05, Vol.355 (1), p.337-340

2008

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Structure–activity relationship study of novel NR2B-selective antagonists with arylamides to avoid reactive metabolites formation

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (20), p.5537-5542

2007

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Synthesis and structure–activity relationships of oxamyl dipeptide caspase inhibitors developed for the treatment of liver disease

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (1), p.199-202

2009

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Effects of the Timing of Fertilizer Application on the Number of Flowers of Japanese Pepper

Journal of the Japanese Society for Horticultural Science, 2013, Vol.82(1), pp.11-13

2013

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Anti SARS-CoV Activity of Extracts from Japanese Pepper (Zanthoxylum piperitum (L.) DC. f. inerme Makino)

Horticultural Research (Japan), 2011, Vol.10(2), pp.267-272

2011

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Relationships between structure and molting hormonal activity of tebufenozide, methoxyfenozide, and their analogs in cultured integument system of Chilo suppressalis Walker

Steroids, 2000-03, Vol.65 (3), p.117-123

2000

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In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit

Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively

Dolutegravir interactions with HIV-1 integrase-DNA: structural rationale for drug resistance and dissociation kinetics

Predicting Key Example Compounds in Competitors' Patent Applications Using Structural Information Alone

Synthesis and SAR Study of Carbamoyl Pyridone Bicycle Derivatives as Potent Inhibitors of Influenza Cap-dependent Endonuclease

Discovery of novel cyclic peptide inhibitors of dengue virus NS2B-NS3 protease with antiviral activity

Effects of Rate and Timing of Fertilizer Application on Yield of Macadamia (Macadamia integrifolia Maiden & Betche) in Japan

Effect of Girdling Treatment on Number of Flowers in Japanese Pepper ‘Budousanshou’ Grafted on Vigorous Rootstock ‘Karasuzanshou’

Conformational Restriction Approach to β‑Secretase (BACE1) Inhibitors: Effect of a Cyclopropane Ring To Induce an Alternative Binding Mode

Discovery of novel 5-hydroxy-4-pyridone-3-carboxy acids as potent inhibitors of influenza Cap-dependent endonuclease

Conformational restriction approach to β-secretase (BACE1) inhibitors III: Effective investigation of the binding mode by combinational use of X-ray analysis, isothermal titration calorimetry and theoretical calculations

Conformational restriction approach to BACE1 inhibitors II: SAR study of the isocytosine derivatives fixed with a cis-cyclopropane ring

Predicting human liver microsomal stability with machine learning techniques

Conformational restriction approach to I2-secretase (BACE1) inhibitors III: Effective investigation of the binding mode by combinational use of X-ray analysis, isothermal titration calorimetry and theoretical calculations

Molting hormonal and larvicidal activities of aliphatic acyl analogs of dibenzoylhydrazine insecticides

Quantitative structure-activity studies of insect growth regulators xiv. Three-dimensional quantitative structure-activity relationship of ecdysone agonists including dibenzoylhydrazine analogs

Discovery of novel and orally active NR2B-selective N-methyl- d-aspartate (NMDA) antagonists, pyridinol derivatives with reduced HERG binding affinity

Discovery of (−)-6-[2-[4-(3-fluorophenyl)-4-hydroxy-1-piperidinyl]-1-hydroxyethyl]-3,4-dihydro-2(1 H)-quinolinone—A potent NR2B-selective N-methyl d-aspartate (NMDA) antagonist for the treatment of pain

Dolutegravir Interactions with HIV-1 Integrase-DNA: Structural Rationale for Drug Resistance and Dissociation Kinetics: e77448

Solid-state characterization of an NR2B selective N-methyl d-aspartate (NMDA) antagonist polymorphs

Structure–activity relationship study of novel NR2B-selective antagonists with arylamides to avoid reactive metabolites formation

Synthesis and structure–activity relationships of oxamyl dipeptide caspase inhibitors developed for the treatment of liver disease

Effects of the Timing of Fertilizer Application on the Number of Flowers of Japanese Pepper

Anti SARS-CoV Activity of Extracts from Japanese Pepper (Zanthoxylum piperitum (L.) DC. f. inerme Makino)

Relationships between structure and molting hormonal activity of tebufenozide, methoxyfenozide, and their analogs in cultured integument system of Chilo suppressalis Walker

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