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Pharmacokinetics, Pharmacodynamics, and Safety of Peficitinib (ASP015K) in Healthy Male Caucasian and Japanese Subjects

Clinical drug investigation, 2020-05, Vol.40 (5), p.469-484

2020

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Pharmacokinetic drug interaction study between overactive bladder drugs mirabegron and tolterodine in Japanese healthy postmenopausal females

Drug metabolism and pharmacokinetics, 2016-12, Vol.31 (6), p.411-416

2016

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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP3652, a Reversible Fatty Acid Amide Hydrolase Inhibitor, in Healthy, Nonelderly, Japanese Men and Elderly, Japanese Men and Women: A Randomized, Double-blind, Placebo-controlled, Single and Multiple Oral Dose, Phase I Study

Clinical therapeutics, 2020-05, Vol.42 (5), p.906-923

2020

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Binding Modes of Two Novel Non-Nucleoside Reverse Transcriptase Inhibitors, YM-215389 and YM-228855, to HIV Type-1 Reverse Transcriptase

Antiviral chemistry & chemotherapy, 2008-06, Vol.19 (3), p.133-141

2008

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Verification of Pharmacodynamic Equivalence of Granule and Capsule Formulations of Bixalomer, A Non-absorbable Phosphate Binder

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2018, Vol.WCP2018, p.PO2-4-21

2018

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Inhibitory Effect of Modified 5′-Capped Short RNA Fragments on Influenza Virus RNA Polymerase Gene Expression

Antiviral chemistry & chemotherapy, 2001-11, Vol.12 (6), p.353-358

2001

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Studies of non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: Synthesis and structure–activity relationships of 2-cyano and 2-hydroxy thiazolidenebenzenesulfonamide derivatives

Bioorganic & medicinal chemistry, 2005-02, Vol.13 (4), p.949-961

2005

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Antisense oligonucleotides directed against the viral RNA polymerase gene enhance survival of mice infected with influenza A

Nature biotechnology, 1999-06, Vol.17 (6), p.583-587

1999

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Studies of nonnucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Design and synthesis of thiazolidenebenzenesulfonamides

Bioorganic & medicinal chemistry, 2004-12, Vol.12 (23), p.6171-6182

2004

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Antisense therapy of influenza

European journal of pharmaceutical sciences, 2001-04, Vol.13 (1), p.61-69

2001

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Specific Inhibition of Influenza Virus RNA Polymerase and Nucleoprotein Genes Expression by Liposomally Endocapsulated Antisense Phosphorothioate Oligonucleotides: Penetration and Localization of Oligonucleotides in Clone 76 Cells

Biochemical and biophysical research communications, 1997-03, Vol.232 (2), p.545-549

1997

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Studies of nonnucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Design and synthesis of thiazolidenebenzenesulfonamides

Bioorganic & medicinal chemistry, 2004-12, Vol.12 (23), p.6171-6182

2004

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Inhibition of Influenza Virus RNA Polymerase and Nucleoprotein Genes Expression by Unmodified, Phosphorothioated, and Liposomally Encapsulated Oligonucleotides

Biochemical and biophysical research communications, 1996-06, Vol.223 (2), p.341-346

1996

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Antisense therapy of influenza: Molecular design and drug delivery of genetic drugs

European journal of pharmaceutical sciences, 2001, Vol.13 (1), p.61-69

2001

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Inhibition of Influenza Virus RNA Polymerase by 5′-Capped Short RNA Fragments

Biochemical and biophysical research communications, 1998-08, Vol.249 (1), p.103-106

1998

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Inhibition of Influenza Virus Replication by Phosphorothioate and Liposomally Endocapsulated Oligonucleotides

Nucleosides & nucleotides, 1998-01, Vol.17 (1-3), p.471-478

1998

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Mechanisms of the inhibition of reverse transcription by unmodified and modified antisense oligonucleotides

FEBS letters, 1993-09, Vol.330 (2), p.161-164

1993

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Antiviral effect of phosphorothioate oligodeoxyribonucleotides complementary to human immunodeficiency virus

Bioorganic & medicinal chemistry, 1995, Vol.3 (1), p.49-54

1995

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Inhibition of Reverse Transcriptase-Mediated cDNA Synthesis by Antisense Oligonucleotides

Nucleosides & nucleotides, 1995-05, Vol.14 (3-5), p.1145-1148

1995

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In vivo anti-influenza A virus activity of antisense oligonucleotides

Japanese Journal of Pharmacology, 1998, Vol.76 (suppl.2), p.286-286

1998

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In vivo anti-influenza A virus activity of antisense oligonucleotides

Japanese journal of pharmacology, 1998, Vol.76, p.286-286

1998

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In Vitro and In Vivo Anti-influenza A Virus Activity of Antisense Oligonucleotides

Nucleosides & nucleotides, 1999-06, Vol.18 (6-7), p.1685-1688

1999

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Anti-Influenza Virus Activities of Nicked and Circular Dumbbell RNA/DNA Chimeric Oligonucleotides

Nucleosides & nucleotides, 1997-07, Vol.16 (7-9), p.1713-1716

1997

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The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3

Nature communications, 2022-12, Vol.13 (1), p.7857-7857, Article 7857

2022

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TRIM48 Promotes ASK1 Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1-Negative Regulator PRMT1

Cell reports (Cambridge), 2017-11, Vol.21 (9), p.2447-2457

2017

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Pharmacokinetics, Pharmacodynamics, and Safety of Peficitinib (ASP015K) in Healthy Male Caucasian and Japanese Subjects

Pharmacokinetic drug interaction study between overactive bladder drugs mirabegron and tolterodine in Japanese healthy postmenopausal females

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP3652, a Reversible Fatty Acid Amide Hydrolase Inhibitor, in Healthy, Nonelderly, Japanese Men and Elderly, Japanese Men and Women: A Randomized, Double-blind, Placebo-controlled, Single and Multiple Oral Dose, Phase I Study

Binding Modes of Two Novel Non-Nucleoside Reverse Transcriptase Inhibitors, YM-215389 and YM-228855, to HIV Type-1 Reverse Transcriptase

Verification of Pharmacodynamic Equivalence of Granule and Capsule Formulations of Bixalomer, A Non-absorbable Phosphate Binder

Inhibitory Effect of Modified 5′-Capped Short RNA Fragments on Influenza Virus RNA Polymerase Gene Expression

Studies of non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: Synthesis and structure–activity relationships of 2-cyano and 2-hydroxy thiazolidenebenzenesulfonamide derivatives

Antisense oligonucleotides directed against the viral RNA polymerase gene enhance survival of mice infected with influenza A

Studies of nonnucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Design and synthesis of thiazolidenebenzenesulfonamides

Antisense therapy of influenza

Specific Inhibition of Influenza Virus RNA Polymerase and Nucleoprotein Genes Expression by Liposomally Endocapsulated Antisense Phosphorothioate Oligonucleotides: Penetration and Localization of Oligonucleotides in Clone 76 Cells

Studies of nonnucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Design and synthesis of thiazolidenebenzenesulfonamides

Inhibition of Influenza Virus RNA Polymerase and Nucleoprotein Genes Expression by Unmodified, Phosphorothioated, and Liposomally Encapsulated Oligonucleotides

Antisense therapy of influenza: Molecular design and drug delivery of genetic drugs

Inhibition of Influenza Virus RNA Polymerase by 5′-Capped Short RNA Fragments

Inhibition of Influenza Virus Replication by Phosphorothioate and Liposomally Endocapsulated Oligonucleotides

Mechanisms of the inhibition of reverse transcription by unmodified and modified antisense oligonucleotides

Antiviral effect of phosphorothioate oligodeoxyribonucleotides complementary to human immunodeficiency virus

Inhibition of Reverse Transcriptase-Mediated cDNA Synthesis by Antisense Oligonucleotides

In vivo anti-influenza A virus activity of antisense oligonucleotides

In vivo anti-influenza A virus activity of antisense oligonucleotides

In Vitro and In Vivo Anti-influenza A Virus Activity of Antisense Oligonucleotides

Anti-Influenza Virus Activities of Nicked and Circular Dumbbell RNA/DNA Chimeric Oligonucleotides

The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3

TRIM48 Promotes ASK1 Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1-Negative Regulator PRMT1

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