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Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

Neurobiology of disease, 2013-03, Vol.51, p.35-42

2013

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role of dopamine oxidation in mitochondrial dysfunction: implications for Parkinson's disease

Journal of bioenergetics and biomembranes, 2009-12, Vol.41 (6), p.469-472

Hastings, Teresa G

2009

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LRRK2 activation in idiopathic Parkinson's disease

Science translational medicine, 2018-07, Vol.10 (451)

2018

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LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease

Neurobiology of disease, 2020-02, Vol.134, p.104626-104626, Article 104626

2020

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NADPH oxidase 2 activity in Parkinson's disease

Neurobiology of disease, 2022-08, Vol.170, p.105754-105754, Article 105754

2022

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Dopamine quinone modifies and decreases the abundance of the mitochondrial selenoprotein glutathione peroxidase 4

Free radical biology & medicine, 2013-12, Vol.65, p.419-427

2013

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Mic60/mitofilin overexpression alters mitochondrial dynamics and attenuates vulnerability of dopaminergic cells to dopamine and rotenone

Neurobiology of disease, 2016-07, Vol.91, p.247-261

2016

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Proteomic identification of dopamine-conjugated proteins from isolated rat brain mitochondria and SH-SY5Y cells

Neurobiology of disease, 2009-06, Vol.34 (3), p.487-500

2009

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α-Synuclein amplifies cytoplasmic peroxide flux and oxidative stress provoked by mitochondrial inhibitors in CNS dopaminergic neurons in vivo

Redox biology, 2020-10, Vol.37, p.101695-101695, Article 101695

2020

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Methamphetamine-Induced Degeneration of Dopaminergic Neurons Involves Autophagy and Upregulation of Dopamine Synthesis

The Journal of neuroscience, 2002-10, Vol.22 (20), p.8951-8960

2002

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Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity

Experimental neurology, 2004-05, Vol.187 (1), p.47-57

2004

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Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: Implications for Parkinson disease

Neurobiology of disease, 2008-03, Vol.29 (3), p.477-489

2008

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Potential Role of Mic60/Mitofilin in Parkinson's Disease

Frontiers in neuroscience, 2019-01, Vol.12, p.898-898

2019

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Transient exposure to rotenone causes degeneration and progressive parkinsonian motor deficits, neuroinflammation, and synucleinopathy

NPJ Parkinson's Disease, 2023-08, Vol.9 (1), p.121-121, Article 121

2023

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α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson's disease

Science translational medicine, 2016-06, Vol.8 (342), p.342ra78

2016

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Alpha‐synuclein inhibits aromatic amino acid decarboxylase activity in dopaminergic cells

Journal of neurochemistry, 2006-11, Vol.99 (4), p.1188-1196

2006

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Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal

Nature chemical biology, 2021-04, Vol.17 (4), p.465-476

2021

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shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model

The Journal of clinical investigation, 2015-07, Vol.125 (7), p.2721-2735

2015

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comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation

Journal of neurochemistry, 2007-09, Vol.102 (6), p.2118-2131

2007

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Parkinson's: Divergent Causes, Convergent Mechanisms

Science (American Association for the Advancement of Science), 2004-05, Vol.304 (5674), p.1120-1122

2004

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Neuroprotective effects of TEMPOL in central and peripheral nervous system models of Parkinson's disease

Biochemical pharmacology, 2005-11, Vol.70 (9), p.1371-1381

2005

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Unregulated Cytosolic Dopamine Causes Neurodegeneration Associated with Oxidative Stress in Mice

The Journal of neuroscience, 2008-01, Vol.28 (2), p.425-433

2008

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LRRK2 regulates production of reactive oxygen species in cell and animal models of Parkinson's disease

Science translational medicine, 2024-10, Vol.16 (767), p.eadl3438

2024

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Could a loss of α‐synuclein function put dopaminergic neurons at risk?

Journal of neurochemistry, 2004-06, Vol.89 (6), p.1318-1324

2004

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Dopamine Quinone Formation and Protein Modification Associated with the Striatal Neurotoxicity of Methamphetamine: Evidence against a Role for Extracellular Dopamine

The Journal of neuroscience, 1999-02, Vol.19 (4), p.1484-1491

1999

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Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

role of dopamine oxidation in mitochondrial dysfunction: implications for Parkinson's disease

LRRK2 activation in idiopathic Parkinson's disease

LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease

NADPH oxidase 2 activity in Parkinson's disease

Dopamine quinone modifies and decreases the abundance of the mitochondrial selenoprotein glutathione peroxidase 4

Mic60/mitofilin overexpression alters mitochondrial dynamics and attenuates vulnerability of dopaminergic cells to dopamine and rotenone

Proteomic identification of dopamine-conjugated proteins from isolated rat brain mitochondria and SH-SY5Y cells

α-Synuclein amplifies cytoplasmic peroxide flux and oxidative stress provoked by mitochondrial inhibitors in CNS dopaminergic neurons in vivo

Methamphetamine-Induced Degeneration of Dopaminergic Neurons Involves Autophagy and Upregulation of Dopamine Synthesis

Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity

Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: Implications for Parkinson disease

Potential Role of Mic60/Mitofilin in Parkinson's Disease

Transient exposure to rotenone causes degeneration and progressive parkinsonian motor deficits, neuroinflammation, and synucleinopathy

α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson's disease

Alpha‐synuclein inhibits aromatic amino acid decarboxylase activity in dopaminergic cells

Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal

shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model

comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation

Parkinson's: Divergent Causes, Convergent Mechanisms

Neuroprotective effects of TEMPOL in central and peripheral nervous system models of Parkinson's disease

Unregulated Cytosolic Dopamine Causes Neurodegeneration Associated with Oxidative Stress in Mice

LRRK2 regulates production of reactive oxygen species in cell and animal models of Parkinson's disease

Could a loss of α‐synuclein function put dopaminergic neurons at risk?

Dopamine Quinone Formation and Protein Modification Associated with the Striatal Neurotoxicity of Methamphetamine: Evidence against a Role for Extracellular Dopamine

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