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Prenatal or postnatal indomethacin exposure and neonatal gut injury associated with isolated intestinal perforation and necrotizing enterocolitis

Journal of perinatology, 2010-12, Vol.30 (12), p.786-793

2010

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Assessment of immunosuppressant drug carcinogenicity: standard and alternative animal models

Human & experimental toxicology, 2000-04, Vol.19 (4), p.261-265

Hastings, K L

2000

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Clinical relevance of preclinical testing for allergic side effects

Toxicology (Amsterdam), 2005-04, Vol.209 (2), p.195-200

2005

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ASSESSMENT OF THE SKIN SENSITIZATION POTENTIAL OF TOPICAL MEDICAMENTS USING THE LOCAL LYMPH NODE ASSAY: AN INTERLABORATORY EVALUATION

Journal of Toxicology and Environmental Health, Part A, 1998-04, Vol.53 (7), p.563-579

1998

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Inhibition of Tumor Necrosis Factor Alpha Alters Resistance to Mycobacterium avium Complex Infection in Mice

Antimicrobial Agents and Chemotherapy, 1998-09, Vol.42 (9), p.2336-2341

1998

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Risk Assessment in Drug Development: Autoimmunity

Journal of Toxicology and Environmental Health, Part A, 2006-05, Vol.69 (9), p.893-898

Hastings, Kenneth L.

2006

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Halogenated anesthetics form liver adducts and antigens that cross-react with halothane-induced antibodies

International archives of allergy and immunology, 1995-09, Vol.108 (1), p.24

1995

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Detection of systemic hypersensitivity to drugs using standard guinea pig assays

Toxicology (Amsterdam), 2003-12, Vol.193 (3), p.203-217

2003

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Pre-clinical methods for detecting the hypersensitivity potential of pharmaceuticals: regulatory considerations

Toxicology (Amsterdam), 2001-02, Vol.158 (1), p.85-89

Hastings, Kenneth L.

2001

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Regulatory Issues of Importance to Developing Anti-HIV Therapeutics

Toxicologic pathology, 1996-05, Vol.24 (3), p.278-280

Hastings, Kenneth L.

1996

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Implications of the new FDA/CDER immunotoxicology guidance for drugs

International immunopharmacology, 2002-10, Vol.2 (11), p.1613-1618

Hastings, Kenneth L.

2002

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Drug-induced phospholipidosis: issues and future directions

Expert opinion on drug safety, 2006-07, Vol.5 (4), p.567-583

2006

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SCREENING FOR ANTIBODIES ASSOCIATED WITH HALOTHANE HEPATITIS

British journal of anaesthesia : BJA, 1991-12, Vol.67 (6), p.722-728

1991

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Safety Evaluation and Risk Assessment Using Immunotoxicology Methods

International journal of toxicology, 1998-05, Vol.17 (3), p.277-296

1998

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Formation and identification of protein adducts to cytosolic proteins in guinea pig liver slices exposed to halothane

Toxicology (Amsterdam), 1992, Vol.73 (3), p.281-295

1992

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Trifluoroacetylation Potentiates the Humoral Immune Response to Halothane in the Guinea PIG

Immunopharmacology and immunotoxicology, 1995-01, Vol.17 (1), p.201-213

1995

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Use of Staphylococcal Enterotoxin A-Induced Lymphoproliferation and Interleukin 2 Production as Indicators of Immunotoxicity

Drug and chemical toxicology (New York, N.Y. 1978), 1994, Vol.17 (1), p.1-14

1994

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A Proposed Testing Framework for Developmental Immunotoxicology (DIT)

Toxicological sciences, 2005-01, Vol.83 (1), p.18-24

2005

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Prospects for Developmental Immunotoxicity Guidance and an Update on ICH S8

Journal of immunotoxicology, 2005-10, Vol.2 (4), p.217-220

Hastings, Kenneth L.

2005

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Evaluation of a Lymph Node Proliferation Assay for its Ability to Detect Pharmaceuticals with Potential to Cause Immune-Mediated Drug Reactions

Journal of immunotoxicology, 2005-01, Vol.2 (1), p.11-20

2005

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Developmental Toxicology Evaluations—Issues with Including Neurotoxicology and Immunotoxicology Assessments in Reproductive Toxicology Studies

Toxicological sciences, 2005-11, Vol.88 (1), p.24-29

2005

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Generation and detection of neoantigens in guinea pig liver slices incubated with halothane

International journal of immunopharmacology, 1991, Vol.13 (4), p.429-435

1991

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Drug metabolites in safety testing

Toxicology and applied pharmacology, 2003-07, Vol.190 (1), p.91-2;author reply 93-4

2003

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Development of the ICH Guidelines for Immunotoxicology Evaluation of Pharmaceuticals Using a Survey of Industry Practices

Journal of immunotoxicology, 2005-07, Vol.2 (3), p.171-180

2005

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Commentary on Hormetic Dose-Response Relationships in Immunology: Occurrence, Quantitative Features of the Dose Response, Mechanistic Foundations, and Clinical Implications

Critical reviews in toxicology, 2005-02, Vol.35 (2-3), p.297-298

Hastings, Kenneth L.

2005

Volltextzugriff (PDF)

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Prenatal or postnatal indomethacin exposure and neonatal gut injury associated with isolated intestinal perforation and necrotizing enterocolitis

Assessment of immunosuppressant drug carcinogenicity: standard and alternative animal models

Clinical relevance of preclinical testing for allergic side effects

ASSESSMENT OF THE SKIN SENSITIZATION POTENTIAL OF TOPICAL MEDICAMENTS USING THE LOCAL LYMPH NODE ASSAY: AN INTERLABORATORY EVALUATION

Inhibition of Tumor Necrosis Factor Alpha Alters Resistance to Mycobacterium avium Complex Infection in Mice

Risk Assessment in Drug Development: Autoimmunity

Halogenated anesthetics form liver adducts and antigens that cross-react with halothane-induced antibodies

Detection of systemic hypersensitivity to drugs using standard guinea pig assays

Pre-clinical methods for detecting the hypersensitivity potential of pharmaceuticals: regulatory considerations

Regulatory Issues of Importance to Developing Anti-HIV Therapeutics

Implications of the new FDA/CDER immunotoxicology guidance for drugs

Drug-induced phospholipidosis: issues and future directions

SCREENING FOR ANTIBODIES ASSOCIATED WITH HALOTHANE HEPATITIS

Safety Evaluation and Risk Assessment Using Immunotoxicology Methods

Formation and identification of protein adducts to cytosolic proteins in guinea pig liver slices exposed to halothane

Trifluoroacetylation Potentiates the Humoral Immune Response to Halothane in the Guinea PIG

Use of Staphylococcal Enterotoxin A-Induced Lymphoproliferation and Interleukin 2 Production as Indicators of Immunotoxicity

A Proposed Testing Framework for Developmental Immunotoxicology (DIT)

Prospects for Developmental Immunotoxicity Guidance and an Update on ICH S8

Evaluation of a Lymph Node Proliferation Assay for its Ability to Detect Pharmaceuticals with Potential to Cause Immune-Mediated Drug Reactions

Developmental Toxicology Evaluations—Issues with Including Neurotoxicology and Immunotoxicology Assessments in Reproductive Toxicology Studies

Generation and detection of neoantigens in guinea pig liver slices incubated with halothane

Drug metabolites in safety testing

Development of the ICH Guidelines for Immunotoxicology Evaluation of Pharmaceuticals Using a Survey of Industry Practices

Commentary on Hormetic Dose-Response Relationships in Immunology: Occurrence, Quantitative Features of the Dose Response, Mechanistic Foundations, and Clinical Implications

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