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ImmTACs for targeted cancer therapy: Why, what, how, and which

Molecular immunology, 2015-10, Vol.67 (2), p.67-74

2015

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Examining the presentation of tumor-associated antigens on peptide-pulsed T2 cells

Oncoimmunology, 2013-11, Vol.2 (11), p.e26840-e26840

2013

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Polyfunctional response by ImmTAC (IMCgp100) redirected CD8+ and CD4+ T cells

Immunology, 2017-11, Vol.152 (3), p.425-438

2017

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CD6 Regulates T-Cell Responses through Activation-Dependent Recruitment of the Positive Regulator SLP-76

Molecular and Cellular Biology, 2006-09, Vol.26 (17), p.6727-6738

2006

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ImmTAC-redirected tumour cell killing induces and potentiates antigen cross-presentation by dendritic cells

Cancer Immunology, Immunotherapy, 2014-05, Vol.63 (5), p.437-448

2014

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Case Report of a Fatal Serious Adverse Event Upon Administration of T Cells Transduced With a MART-1-specific T-cell Receptor

Molecular therapy, 2015-09, Vol.23 (9), p.1541-1550

2015

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Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-suppressed Subjects by Engineered Immune-mobilizing T-cell Receptors

Molecular therapy, 2016-11, Vol.24 (11), p.1913-1925

2016

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Second Correction for Hassan et al., "CD6 Regulates T-Cell Responses through Activation-Dependent Recruitment of the Positive Regulator SLP-76"

Molecular and cellular biology, 2019-04, Vol.39 (7)

2019

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Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1- and LAGE-1-positive tumors

Cancer Immunology, Immunotherapy, 2013-04, Vol.62 (4), p.773-785

2013

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Frontline: Optimal T cell activation requires the engagement of CD6 and CD166

European journal of immunology, 2004-04, Vol.34 (4), p.930-940

2004

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Strategies to generate biological reagents for kinase drug discovery

Expert opinion on drug discovery, 2011-12, Vol.6 (12), p.1215-1225

2011

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High-yield production and characterization of biologically active GST-tagged human topoisomerase IIα protein in insect cells for the development of a high-throughput assay

Protein expression and purification, 2011-04, Vol.76 (2), p.165-172

2011

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Development of an insect-cell-based assay for detection of kinase inhibition using NF-κB-inducing kinase as a paradigm

Biochemical journal, 2009-04, Vol.419 (1), p.65-73

2009

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BacMam recombinant baculovirus in transporter expression: A study of BCRP and OATP1B1

Protein expression and purification, 2006-06, Vol.47 (2), p.591-598

2006

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Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

European journal of biochemistry, 2000-09, Vol.267 (18), p.5699-5710

2000

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Polyfunctional response by Imm TAC ( IMC gp100) redirected CD 8 + and CD 4 + T cells

Immunology, 2017-11, Vol.152 (3), p.425-438

2017

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Abstract 3655: Biomarker strategy to guide the clinical development of ImmTACTM molecules, a novel class of bispecific T cell engaging biologic drugs

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3655-3655

2017

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Abstract 1329: Development of the first optimised “off the shelf” MAGE-A4 targeting TCR-NK cells for advancement into the clinic for the treatment of solid tumors

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.1329-1329

2024

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Abstract CT106: A phase I/IIa study of IMCgp100: Partial and complete durable responses with a novel first-in-class immunotherapy for advanced melanoma

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.CT106-CT106

2015

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Baculoviruses and Mammalian Cell‐based Assays for Drug Screening

Advances in Virus Research, 2006, Vol.68, p.255-286

2006

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ImmTACs for targeted cancer therapy: Why, what, how, and which

Examining the presentation of tumor-associated antigens on peptide-pulsed T2 cells

Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma

Polyfunctional response by ImmTAC (IMCgp100) redirected CD8+ and CD4+ T cells

CD6 Regulates T-Cell Responses through Activation-Dependent Recruitment of the Positive Regulator SLP-76

Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells

ImmTAC-redirected tumour cell killing induces and potentiates antigen cross-presentation by dendritic cells

Monoclonal TCR-redirected tumor cell killing

An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific (ImmTAC) molecules

Case Report of a Fatal Serious Adverse Event Upon Administration of T Cells Transduced With a MART-1-specific T-cell Receptor

Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-suppressed Subjects by Engineered Immune-mobilizing T-cell Receptors

Second Correction for Hassan et al., "CD6 Regulates T-Cell Responses through Activation-Dependent Recruitment of the Positive Regulator SLP-76"

Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1- and LAGE-1-positive tumors

Frontline: Optimal T cell activation requires the engagement of CD6 and CD166

Strategies to generate biological reagents for kinase drug discovery

High-yield production and characterization of biologically active GST-tagged human topoisomerase IIα protein in insect cells for the development of a high-throughput assay

Development of an insect-cell-based assay for detection of kinase inhibition using NF-κB-inducing kinase as a paradigm

BacMam recombinant baculovirus in transporter expression: A study of BCRP and OATP1B1

Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

Polyfunctional response by Imm TAC ( IMC gp100) redirected CD 8 + and CD 4 + T cells

Abstract 3655: Biomarker strategy to guide the clinical development of ImmTACTM molecules, a novel class of bispecific T cell engaging biologic drugs

An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific

Abstract 1329: Development of the first optimised “off the shelf” MAGE-A4 targeting TCR-NK cells for advancement into the clinic for the treatment of solid tumors

Abstract CT106: A phase I/IIa study of IMCgp100: Partial and complete durable responses with a novel first-in-class immunotherapy for advanced melanoma

Baculoviruses and Mammalian Cell‐based Assays for Drug Screening

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