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NDI-010976, A Potent, Liver-Directed, Oral Inhibitor of Acetyl Coa Carboxylase for Non-Alcoholic Steatohepatitis: A Phase 1 Single Ascending Dose Study in Healthy Volunteers

Journal of hepatology, 2016, Vol.64 (2), p.S501-S502

2016

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LP30 : Liver-directed allosteric inhibitors of acetyl-coa carboxylase favorably impact pathophysiology in the progression from nafld to nash and hepatocellular carcinoma, including hepatic steatosis, inflammation, and fibrosis

Journal of hepatology, 2015-04, Vol.62, p.S279-S279

2015

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NDI-010976, a Potent, Liver-Directed, Oral Inhibitor of Acetyl Coa Carboxylase for Non-Alcoholic Steatohepatitis: Pharmacodynamic Effects on Hepatic De Novo Lipogenesis in Obese but Otherwise Healthy Adult Male Volunteers

Journal of hepatology, 2016, Vol.64 (2), p.S190-S191

2016

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FRI-355 - NDI-010976, A Potent, Liver-Directed, Oral Inhibitor of Acetyl Coa Carboxylase for Non-Alcoholic Steatohepatitis: A Phase 1 Single Ascending Dose Study in Healthy Volunteers

Journal of hepatology, 2016, Vol.64 (2), p.S501-S502

2016

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FRI-087 - ACC inhibitor demonstrates potent anti-fibrotic activity in vitro and in vivo

Journal of hepatology, 2018-04, Vol.68, p.S399-S400

2018

Volltextzugriff (PDF)

ACC inhibitor demonstrates potent anti-fibrotic activity in vitro and in vivo

Journal of hepatology, 2018-04, Vol.68, p.S399-S400

2018

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PS108 - NDI-010976, a Potent, Liver-Directed, Oral Inhibitor of Acetyl Coa Carboxylase for Non-Alcoholic Steatohepatitis: Pharmacodynamic Effects on Hepatic De Novo Lipogenesis in Obese but Otherwise Healthy Adult Male Volunteers

Journal of hepatology, 2016, Vol.64 (2), p.S190-S191

2016

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Old World nonhuman primate models of type 2 diabetes mellitus

ILAR journal, 2006, Vol.47 (3), p.259-271

2006

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Protein Farnesyltransferase: Measurement of Enzymatic Activity in 96-Well Format Using TopCount Microplate Scintillation Counting Technology

Analytical biochemistry, 1995-04, Vol.226 (2), p.268-278

Harwood, H.J.

1995

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Oleochemicals as a fuel: mechanical and economic feasibility [Vegetable oils in diesel]

Journal of the American Oil Chemists' Society, 1984-02, Vol.61 (2), p.315-324

Harwood, Henrick J.

1984

Volltextzugriff (PDF)

2.P.40 Discovery of the squalene synthetase inhibitor CP-340,868

Atherosclerosis, 1997-10, Vol.134 (1-2), p.125-125

1997

Volltextzugriff (PDF)

Investigations of the effects of synthetic saponins on cholesterol absorption and serum cholesterol levels

Atherosclerosis, 1994-09, Vol.109 (1), p.88-88

1994

Volltextzugriff (PDF)

Pharmacologic consequences of cholesterol absorption inhibitin: alteration in cholesterol metabolism and reduction in plasma cholesterol concentration induced by the synthetic saponin beta-tigogenin cellobioside (CP-88818; tiqueside)

Journal of lipid research, 1993-03, Vol.34 (3)

1993

Volltextzugriff (PDF)

Analysis of the 400 MHz PMR spectrum of poly(2-vinylbenzofuran)

Journal of polymer science. Part B, Polymer physics, 1988-06, Vol.26 (6), p.1331-1335

1988

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Analysis of the 300 MHz PMR spectrum of poly(p-bromostyrene)

Polymer bulletin (Berlin, Germany), 1987-07, Vol.18 (1), p.27-32

1987

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Study of grafting ethylene oxide onto gelatin by one- and hetero two-dimensional 13C n.m.r. spectroscopy

Polymer (Guilford), 1987-07, Vol.28 (8), p.1403-1406

1987

Volltextzugriff (PDF)

Derivatives of the fatty acids

Progress in the chemistry of fats and other lipids, 1952, Vol.1, p.127-174

Harwood, H.J.

1952

Volltextzugriff (PDF)

Ascorbic acid regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol synthesis in guinea pig liver

Biochimica et biophysica acta, 1985-03, Vol.834 (1), p.134-138

1985

Volltextzugriff (PDF)

Chronic toxicity of dichloroacetate: Possible relation to thiamine deficiency in rats

Fundamental and applied toxicology, 1990-02, Vol.14 (2), p.327-337

1990

Volltextzugriff (PDF)

Remnant radio-loud AGN in the Herschel-ATLAS field

Monthly notices of the Royal Astronomical Society, 2018-04, Vol.475 (4), p.4557-4578

2018

Volltextzugriff (PDF)

Challenges and opportunities in understanding dementia and delirium in the acute hospital

PLoS medicine, 2017-03, Vol.14 (3), p.e1002247-e1002247

2017

Volltextzugriff (PDF)

Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions

European journal of pharmaceutical sciences, 2016-06, Vol.88, p.70-82

2016

Volltextzugriff (PDF)

The SF-36: A simple, effective measure of mobility-disability for epidemiological studies

The Journal of nutrition, health & aging, 2009, Vol.13 (1), p.57-62

2009

Volltextzugriff (PDF)

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NDI-010976, A Potent, Liver-Directed, Oral Inhibitor of Acetyl Coa Carboxylase for Non-Alcoholic Steatohepatitis: A Phase 1 Single Ascending Dose Study in Healthy Volunteers

LP30 : Liver-directed allosteric inhibitors of acetyl-coa carboxylase favorably impact pathophysiology in the progression from nafld to nash and hepatocellular carcinoma, including hepatic steatosis, inflammation, and fibrosis

NDI-010976, a Potent, Liver-Directed, Oral Inhibitor of Acetyl Coa Carboxylase for Non-Alcoholic Steatohepatitis: Pharmacodynamic Effects on Hepatic De Novo Lipogenesis in Obese but Otherwise Healthy Adult Male Volunteers

FRI-355 - NDI-010976, A Potent, Liver-Directed, Oral Inhibitor of Acetyl Coa Carboxylase for Non-Alcoholic Steatohepatitis: A Phase 1 Single Ascending Dose Study in Healthy Volunteers

FRI-087 - ACC inhibitor demonstrates potent anti-fibrotic activity in vitro and in vivo

ACC inhibitor demonstrates potent anti-fibrotic activity in vitro and in vivo

PS108 - NDI-010976, a Potent, Liver-Directed, Oral Inhibitor of Acetyl Coa Carboxylase for Non-Alcoholic Steatohepatitis: Pharmacodynamic Effects on Hepatic De Novo Lipogenesis in Obese but Otherwise Healthy Adult Male Volunteers

Old World nonhuman primate models of type 2 diabetes mellitus

Protein Farnesyltransferase: Measurement of Enzymatic Activity in 96-Well Format Using TopCount Microplate Scintillation Counting Technology

Oleochemicals as a fuel: mechanical and economic feasibility [Vegetable oils in diesel]

2.P.40 Discovery of the squalene synthetase inhibitor CP-340,868

Investigations of the effects of synthetic saponins on cholesterol absorption and serum cholesterol levels

Pharmacologic consequences of cholesterol absorption inhibitin: alteration in cholesterol metabolism and reduction in plasma cholesterol concentration induced by the synthetic saponin beta-tigogenin cellobioside (CP-88818; tiqueside)

Analysis of the 400 MHz PMR spectrum of poly(2-vinylbenzofuran)

Analysis of the 300 MHz PMR spectrum of poly(p-bromostyrene)

Study of grafting ethylene oxide onto gelatin by one- and hetero two-dimensional 13C n.m.r. spectroscopy

Derivatives of the fatty acids

Ascorbic acid regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol synthesis in guinea pig liver

Chronic toxicity of dichloroacetate: Possible relation to thiamine deficiency in rats

European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: Part 1. epidemiology, diagnostics and prevention

Remnant radio-loud AGN in the Herschel-ATLAS field

European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: Part 2. Treatment

Challenges and opportunities in understanding dementia and delirium in the acute hospital

Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions

The SF-36: A simple, effective measure of mobility-disability for epidemiological studies

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