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Shuttle peptide delivers base editor RNPs to rhesus monkey airway epithelial cells in vivo

Nature communications, 2023-12, Vol.14 (1), p.8051-8051, Article 8051

2023

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KLRC1 knockout overcomes HLA-E-mediated inhibition and improves NK cell antitumor activity against solid tumors

Frontiers in immunology, 2023-08, Vol.14, p.1231916-1231916

2023

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Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine

Drug metabolism and disposition, 2009-09, Vol.37 (9), p.1793

2009

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Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic-mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer

Molecular oncology, 2023-10, Vol.17 (10), p.2109-2125

2023

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Multiple metabolic pathways fuel the truncated tricarboxylic acid cycle of the prostate to sustain constant citrate production and secretion

Molecular metabolism (Germany), 2022-08, Vol.62, p.101516-101516, Article 101516

2022

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Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells

BMC molecular biology, 2010-01, Vol.11 (1), p.9-9, Article 9

2010

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Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2006-06, Vol.141B (4), p.374-382

2006

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Modulation of the Human Glucuronosyltransferase UGT1A Pathway by Splice Isoform Polypeptides Is Mediated through Protein-Protein Interactions

The Journal of biological chemistry, 2010-02, Vol.285 (6), p.3600-3607

2010

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Immunohistochemical expression of conjugating UGT1A-derived isoforms in normal and tumoral drug-metabolizing tissues in humans

The Journal of pathology, 2011-02, Vol.223 (3), p.425-435

2011

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Intralesional Treatment of Basal Cell Carcinoma in a Genetically Inducible Mouse Model

Skin (Milwood, N.Y.), 2023-03, Vol.7 (2), p.s172

2023

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UGT genomic diversity: beyond gene duplication

Drug metabolism reviews, 2010-02, Vol.42 (1), p.24-44

2010

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Protein-protein interactions between the bilirubin-conjugating UDP-glucuronosyltransferase UGT1A1 and its shorter isoform 2 regulatory partner derived from alternative splicing

Biochemical journal, 2013-02, Vol.450 (1), p.107-114

2013

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Refining the UGT1A haplotype associated with irinotecan-induced hematological toxicity in metastatic colorectal cancer patients treated with 5-fluorouracil/irinotecan-based regimens

The Journal of pharmacology and experimental therapeutics, 2013-04, Vol.345 (1), p.95

2013

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In vitro investigation of human UDP-glucuronosyltransferase isoforms responsible for tacrolimus glucuronidation: predominant contribution of UGT1A4

Drug metabolism and disposition, 2011-07, Vol.39 (7), p.1127

2011

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P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder

Human molecular genetics, 2006-08, Vol.15 (16), p.2438-2445

2006

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Transcriptional diversity at the UGT2B7 locus is dictated by extensive pre-mRNA splicing mechanisms that give rise to multiple mRNA splice variants

Pharmacogenetics and genomics, 2011-10, Vol.21 (10), p.631-641

2011

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Protein–protein interactions between the bilirubin-conjugating UDPglucuronosyltransferase UGT1A1 and its shorter isoform 2 regulatory partner derived from alternative splicing

Biochemical journal, 2013-02, Vol.450 (1), p.107-114

2013

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Comunicación e Identidad Indígena en el Ciberespacio. Dinámicas Culturales, Subjetivas y Virtuales en el Caso de una Mujer Kamëntšá y su Facebook

Carvajal Martínez, Mario Harvey

2019

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ProQuest

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro

Drug metabolism and disposition, 2010-10, Vol.38 (10), p.1785

2010

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Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism

Human mutation, 2009-09, Vol.30 (9), p.1310-1319

2009

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Abstract 3700: Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic-mitochondrial tricarboxylic acid cycle in prostate cancer

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.3700-3700

2023

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Phase II Drug-Metabolizing Polymorphisms and Smoking Predict Recurrence of Non-Muscle-Invasive Bladder Cancer: A Gene-Smoking Interaction

Cancer prevention research (Philadelphia, Pa.), 2016-02, Vol.9 (2), p.189-195

2016

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Gene interactions in depression: pathways out of darkness

Trends in genetics, 2007-11, Vol.23 (11), p.547-556

2007

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Polymorphisms in the neuronal isoform of tryptophan hydroxylase 2 are associated with bipolar disorder in French Canadian pedigrees

Psychiatric genetics, 2007-02, Vol.17 (1), p.17-22

2007

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UGT genomic diversity: beyond gene duplication

Drug metabolism reviews, 2009-09, p.90930040245068-21

2009

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Shuttle peptide delivers base editor RNPs to rhesus monkey airway epithelial cells in vivo

KLRC1 knockout overcomes HLA-E-mediated inhibition and improves NK cell antitumor activity against solid tumors

Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine

Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic-mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer

Multiple metabolic pathways fuel the truncated tricarboxylic acid cycle of the prostate to sustain constant citrate production and secretion

Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells

Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder

Modulation of the Human Glucuronosyltransferase UGT1A Pathway by Splice Isoform Polypeptides Is Mediated through Protein-Protein Interactions

Immunohistochemical expression of conjugating UGT1A-derived isoforms in normal and tumoral drug-metabolizing tissues in humans

Intralesional Treatment of Basal Cell Carcinoma in a Genetically Inducible Mouse Model

UGT genomic diversity: beyond gene duplication

Protein-protein interactions between the bilirubin-conjugating UDP-glucuronosyltransferase UGT1A1 and its shorter isoform 2 regulatory partner derived from alternative splicing

Refining the UGT1A haplotype associated with irinotecan-induced hematological toxicity in metastatic colorectal cancer patients treated with 5-fluorouracil/irinotecan-based regimens

In vitro investigation of human UDP-glucuronosyltransferase isoforms responsible for tacrolimus glucuronidation: predominant contribution of UGT1A4

P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder

Transcriptional diversity at the UGT2B7 locus is dictated by extensive pre-mRNA splicing mechanisms that give rise to multiple mRNA splice variants

Protein–protein interactions between the bilirubin-conjugating UDPglucuronosyltransferase UGT1A1 and its shorter isoform 2 regulatory partner derived from alternative splicing

Comunicación e Identidad Indígena en el Ciberespacio. Dinámicas Culturales, Subjetivas y Virtuales en el Caso de una Mujer Kamëntšá y su Facebook

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro

Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism

Abstract 3700: Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic-mitochondrial tricarboxylic acid cycle in prostate cancer

Phase II Drug-Metabolizing Polymorphisms and Smoking Predict Recurrence of Non-Muscle-Invasive Bladder Cancer: A Gene-Smoking Interaction

Gene interactions in depression: pathways out of darkness

Polymorphisms in the neuronal isoform of tryptophan hydroxylase 2 are associated with bipolar disorder in French Canadian pedigrees

UGT genomic diversity: beyond gene duplication

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