UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 526

Sortiert nach

Design and synthesis of a library of lead-like 2,4-bisheterocyclic substituted thiophenes as selective Dyrk/Clk inhibitors

PloS one, 2014-03, Vol.9 (3), p.e87851

2014

Volltextzugriff (PDF)

Cushing’s Syndrome: Development of Highly Potent and Selective CYP11B1 Inhibitors of the (Pyridylmethyl)pyridine Type

Journal of medicinal chemistry, 2013-08, Vol.56 (15), p.6022-6032

2013

Volltextzugriff (PDF)

3-Pyridyl substituted aliphatic cycles as CYP11B2 inhibitors: aromaticity abolishment of the core significantly increased selectivity over CYP1A2

PloS one, 2012-11, Vol.7 (11), p.e48048

2012

Volltextzugriff (PDF)

Recent progress in pharmaceutical therapies for castration-resistant prostate cancer

International Journal of Molecular Sciences, 2013-07, Vol.14 (7), p.13958-13978

2013

Volltextzugriff (PDF)

In-depth Profiling of MvfR-Regulated Small Molecules in Pseudomonas aeruginosa after Quorum Sensing Inhibitor Treatment

Frontiers in microbiology, 2017-05, Vol.8, p.924-924

2017

Volltextzugriff (PDF)

Validation of PqsD as an Anti-biofilm Target in Pseudomonas aeruginosa by Development of Small-Molecule Inhibitors

Journal of the American Chemical Society, 2012-10, Vol.134 (39), p.16143-16146

2012

Volltextzugriff (PDF)

Inhibition of aldosterone synthase (CYP11B2) by torasemide prevents atrial fibrosis and atrial fibrillation in mice

Journal of molecular and cellular cardiology, 2015-08, Vol.85, p.140-150

2015

Volltextzugriff (PDF)

Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction

International journal of molecular sciences, 2020-10, Vol.21 (19), p.7102

2020

Volltextzugriff (PDF)

The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis[S]

Journal of lipid research, 2014-06, Vol.55 (6), p.1087-1097

2014

Volltextzugriff (PDF)

Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections

Journal of medicinal chemistry, 2016-07, Vol.59 (13), p.5929-5969

2016

Volltextzugriff (PDF)

Highly Potent and Selective Nonsteroidal Dual Inhibitors of CYP17/CYP11B2 for the Treatment of Prostate Cancer To Reduce Risks of Cardiovascular Diseases

Journal of medicinal chemistry, 2013-08, Vol.56 (15), p.6101-6107

2013

Volltextzugriff (PDF)

Novel Highly Potent and Selective Nonsteroidal Aromatase Inhibitors: Synthesis, Biological Evaluation and Structure−Activity Relationships Investigation

Journal of medicinal chemistry, 2010-07, Vol.53 (14), p.5347-5351

2010

Volltextzugriff (PDF)

Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections

ACS central science, 2023-12, Vol.9 (12), p.2205-2215

2023

Volltextzugriff (PDF)

17β-Hydroxysteroid Dehydrogenase Type 2 Inhibition: Discovery of Selective and Metabolically Stable Compounds Inhibiting Both the Human Enzyme and Its Murine Ortholog

PloS one, 2015-07, Vol.10 (7), p.e0134754-e0134754

2015

Volltextzugriff (PDF)

The Role of Fluorine Substitution in Biphenyl Methylene Imidazole-Type CYP17 Inhibitors for the Treatment of Prostate Carcinoma

ChemMedChem, 2010-06, Vol.5 (6), p.899-910

2010

Volltextzugriff (PDF)

Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols

Pharmaceuticals (Basel, Switzerland), 2020-08, Vol.13 (8), p.186

2020

Volltextzugriff (PDF)

Aldosterone synthase inhibitors as promising treatments for mineralocorticoid dependent cardiovascular and renal diseases

Journal of medicinal chemistry, 2014-06, Vol.57 (12), p.5011-5022

2014

Volltextzugriff (PDF)

Pharmacophore Modeling and in Silico/in Vitro Screening for Human Cytochrome P450 11B1 and Cytochrome P450 11B2 Inhibitors

Frontiers in chemistry, 2017-12, Vol.5, p.104-104

2017

Volltextzugriff (PDF)

First Selective CYP11B1 Inhibitors for the Treatment of Cortisol-Dependent Diseases

ACS medicinal chemistry letters, 2011-01, Vol.2 (1), p.2-6

2011

Volltextzugriff (PDF)

Tetrahydropyrroloquinolinone Type Dual Inhibitors of Aromatase/Aldosterone Synthase as a Novel Strategy for Breast Cancer Patients with Elevated Cardiovascular Risks

Journal of medicinal chemistry, 2013-01, Vol.56 (2), p.460-470

2013

Volltextzugriff (PDF)

Design, Synthesis, and 3D QSAR of Novel Potent and Selective Aromatase Inhibitors

Journal of medicinal chemistry, 2004-12, Vol.47 (27), p.6792-6803

2004

Volltextzugriff (PDF)

Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa

Journal of the American Chemical Society, 2018-02, Vol.140 (7), p.2537-2545

2018

Volltextzugriff (PDF)

Pharmacophore Modeling and in Silico Screening for New P450 19 (Aromatase) Inhibitors

Journal of chemical information and modeling, 2006-05, Vol.46 (3), p.1301-1311

2006

Volltextzugriff (PDF)

Selective Dual Inhibitors of CYP19 and CYP11B2: Targeting Cardiovascular Diseases Hiding in the Shadow of Breast Cancer

Journal of medicinal chemistry, 2012-08, Vol.55 (16), p.7080-7089

2012

Volltextzugriff (PDF)

Antibiotic-free nanotherapeutics: Ultra-small, mucus-penetrating solid lipid nanoparticles enhance the pulmonary delivery and anti-virulence efficacy of novel quorum sensing inhibitors

Journal of controlled release, 2014-10, Vol.192, p.131-140

2014

Volltextzugriff (PDF)

1 – 25 von 526

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(474)
Mit Volltextzugriff
(513)

Publikationsform

Sprache

Englisch
(511)
Deutsch
(24)
Japanisch
(23)

Erscheinungsjahr

n.n

Thema

Science & Technology
(320)
Life Sciences & Biomedicine
(286)
Pharmacology & Pharmacy
(209)
Chemistry, Medicinal
(200)
Humans
(197)
Structure-Activity Relationship
(126)
Chemistry
(114)
Animals
(105)
Physical Sciences
(99)
Biological And Medical Sciences
(97)
Enzyme Inhibitors - Pharmacology
(96)
Medical Sciences
(93)
Pharmacology. Drug Treatments
(85)
Biochemistry & Molecular Biology
(78)
Enzyme Inhibitors - Chemistry
(73)
Male
(67)
Enzyme Inhibitors - Chemical Synthesis
(57)
Models, Molecular
(56)
Molecular Structure
(56)
Female
(55)

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 90 Tagen
(2)

Menü

Weitere Dienste

Einstellungen

Design and synthesis of a library of lead-like 2,4-bisheterocyclic substituted thiophenes as selective Dyrk/Clk inhibitors

Cushing’s Syndrome: Development of Highly Potent and Selective CYP11B1 Inhibitors of the (Pyridylmethyl)pyridine Type

3-Pyridyl substituted aliphatic cycles as CYP11B2 inhibitors: aromaticity abolishment of the core significantly increased selectivity over CYP1A2

Recent progress in pharmaceutical therapies for castration-resistant prostate cancer

In-depth Profiling of MvfR-Regulated Small Molecules in Pseudomonas aeruginosa after Quorum Sensing Inhibitor Treatment

Validation of PqsD as an Anti-biofilm Target in Pseudomonas aeruginosa by Development of Small-Molecule Inhibitors

Inhibition of aldosterone synthase (CYP11B2) by torasemide prevents atrial fibrosis and atrial fibrillation in mice

Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction

The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis[S]

Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections

Highly Potent and Selective Nonsteroidal Dual Inhibitors of CYP17/CYP11B2 for the Treatment of Prostate Cancer To Reduce Risks of Cardiovascular Diseases

Novel Highly Potent and Selective Nonsteroidal Aromatase Inhibitors: Synthesis, Biological Evaluation and Structure−Activity Relationships Investigation

Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections

17β-Hydroxysteroid Dehydrogenase Type 2 Inhibition: Discovery of Selective and Metabolically Stable Compounds Inhibiting Both the Human Enzyme and Its Murine Ortholog

The Role of Fluorine Substitution in Biphenyl Methylene Imidazole-Type CYP17 Inhibitors for the Treatment of Prostate Carcinoma

Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols

Aldosterone synthase inhibitors as promising treatments for mineralocorticoid dependent cardiovascular and renal diseases

Pharmacophore Modeling and in Silico/in Vitro Screening for Human Cytochrome P450 11B1 and Cytochrome P450 11B2 Inhibitors

First Selective CYP11B1 Inhibitors for the Treatment of Cortisol-Dependent Diseases

Tetrahydropyrroloquinolinone Type Dual Inhibitors of Aromatase/Aldosterone Synthase as a Novel Strategy for Breast Cancer Patients with Elevated Cardiovascular Risks

Design, Synthesis, and 3D QSAR of Novel Potent and Selective Aromatase Inhibitors

Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa

Pharmacophore Modeling and in Silico Screening for New P450 19 (Aromatase) Inhibitors

Selective Dual Inhibitors of CYP19 and CYP11B2: Targeting Cardiovascular Diseases Hiding in the Shadow of Breast Cancer

Antibiotic-free nanotherapeutics: Ultra-small, mucus-penetrating solid lipid nanoparticles enhance the pulmonary delivery and anti-virulence efficacy of novel quorum sensing inhibitors

Suchergebnisse filtern