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Spatial defects nanoengineering for bipolar conductivity in MoS2

Nature communications, 2020-07, Vol.11 (1), p.3463-3463, Article 3463

2020

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Translational two-pore PBPK model to characterize whole-body disposition of different-size endogenous and exogenous proteins

Journal of pharmacokinetics and pharmacodynamics, 2024-05

2024

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Preclinical Assessment of a MUC12-Targeted BiTE (Bispecific T-cell Engager) Molecule

Molecular cancer therapeutics, 2021-10, Vol.20 (10), p.1977-1987

2021

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GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys

Cell reports. Medicine, 2021-05, Vol.2 (5), p.100263, Article 100263

2021

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Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling

The AAPS journal, 2017-03, Vol.19 (2), p.510-519

2017

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Computational Analysis of Cytokine Release Following Bispecific T-Cell Engager Therapy: Applications of a Logic-Based Model

Frontiers in oncology, 2022-03, Vol.12, p.818641-818641

2022

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Functional Interfacing of Rhodospirillum rubrum Chromatophores to a Conducting Support for Capture and Conversion of Solar Energy

The journal of physical chemistry. B, 2013-09, Vol.117 (38), p.11249-11259

2013

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Combinatorial Chemotherapeutic Efficacy in Non-Hodgkin Lymphoma Can Be Predicted by a Signaling Model of CD20 Pharmacodynamics

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (7), p.1632-1641

2012

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Interspecies Scaling of Receptor-Mediated Pharmacokinetics and Pharmacodynamics of Type I Interferons

Pharmaceutical research, 2010-05, Vol.27 (5), p.920-932

2010

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Erratum to: Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling

The AAPS journal, 2017-03, Vol.19 (2), p.597-597

2017

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Navigating Between Right, Wrong, and Relevant: The Use of Mathematical Modeling in Preclinical Decision Making

Frontiers in pharmacology, 2022-04, Vol.13, p.860881

2022

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Prediction of Survival Benefit of Filgrastim in Adult and Pediatric Patients With Acute Radiation Syndrome

Clinical and translational science, 2020-07, Vol.13 (4), p.807-817

2020

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Simulations of site-specific target-mediated pharmacokinetic models for guiding the development of bispecific antibodies

Journal of pharmacokinetics and pharmacodynamics, 2015-02, Vol.42 (1), p.1-18

2015

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A cell-level model of pharmacodynamics-mediated drug disposition

Journal of pharmacokinetics and pharmacodynamics, 2016-10, Vol.43 (5), p.513-527

2016

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Ubiquity: a framework for physiological/mechanism-based pharmacokinetic/pharmacodynamic model development and deployment

Journal of pharmacokinetics and pharmacodynamics, 2014-04, Vol.41 (2), p.141-151

2014

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Structural and functional proteomics of intracytoplasmic membrane assembly in Rhodobacter sphaeroides

Journal of molecular microbiology and biotechnology, 2013-01, Vol.23 (1-2), p.48-62

2013

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Differential pharmacodynamic effects of paclitaxel formulations in an intracranial rat brain tumor model

The Journal of pharmacology and experimental therapeutics, 2010-02, Vol.332 (2), p.479-488

2010

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718 AMG 509, a STEAP1 x CD3 bispecific XmAb® 2+1 immune therapy, exhibits avidity-driven binding and preferential killing of high STEAP1-expressing prostate and Ewing sarcoma cancer cells

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A760-A760

2020

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Absorption, Distribution, Metabolism, and Excretion (ADME) Studies of Biotherapeutics for Autoimmune and Inflammatory Conditions

The AAPS journal, 2012-12, Vol.14 (4), p.714-727

2012

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Achieving Agility in Disaster Management

International journal of information systems for crisis response and management, 2009-01, Vol.1 (1), p.1-11

Harrold, John R

2009

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Pharmacokinetic–pharmacodynamic modelling of neutrophil response to G‐CSF in healthy subjects and patients with chemotherapy‐induced neutropenia

British journal of clinical pharmacology, 2018-05, Vol.84 (5), p.911-925

2018

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Clinically relevant cancer chemotherapy dose scheduling via mixed-integer optimization

Computers & chemical engineering, 2009-12, Vol.33 (12), p.2042-2054

2009

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Abstract 3364: Preclinical evaluation of BiTE®immune therapy targeting MUC17 or CLDN18.2 for gastric cancer

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.3364-3364

2020

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Quantification of Radiation Injury on Neutropenia and the Link between Absolute Neutrophil Count Time Course and Overall Survival in Nonhuman Primates Treated with G-CSF

Pharmaceutical research, 2020-06, Vol.37 (6), p.102, Article 102

2020

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Pharmacodynamic model for chemoradiotherapy-induced thrombocytopenia in mice

Journal of pharmacokinetics and pharmacodynamics, 2015-12, Vol.42 (6), p.709-720

2015

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Spatial defects nanoengineering for bipolar conductivity in MoS2

Translational two-pore PBPK model to characterize whole-body disposition of different-size endogenous and exogenous proteins

Preclinical Assessment of a MUC12-Targeted BiTE (Bispecific T-cell Engager) Molecule

GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys

Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling

Computational Analysis of Cytokine Release Following Bispecific T-Cell Engager Therapy: Applications of a Logic-Based Model

Functional Interfacing of Rhodospirillum rubrum Chromatophores to a Conducting Support for Capture and Conversion of Solar Energy

Combinatorial Chemotherapeutic Efficacy in Non-Hodgkin Lymphoma Can Be Predicted by a Signaling Model of CD20 Pharmacodynamics

Interspecies Scaling of Receptor-Mediated Pharmacokinetics and Pharmacodynamics of Type I Interferons

Erratum to: Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling

Navigating Between Right, Wrong, and Relevant: The Use of Mathematical Modeling in Preclinical Decision Making

Prediction of Survival Benefit of Filgrastim in Adult and Pediatric Patients With Acute Radiation Syndrome

Simulations of site-specific target-mediated pharmacokinetic models for guiding the development of bispecific antibodies

A cell-level model of pharmacodynamics-mediated drug disposition

Ubiquity: a framework for physiological/mechanism-based pharmacokinetic/pharmacodynamic model development and deployment

Structural and functional proteomics of intracytoplasmic membrane assembly in Rhodobacter sphaeroides

Differential pharmacodynamic effects of paclitaxel formulations in an intracranial rat brain tumor model

718 AMG 509, a STEAP1 x CD3 bispecific XmAb® 2+1 immune therapy, exhibits avidity-driven binding and preferential killing of high STEAP1-expressing prostate and Ewing sarcoma cancer cells

Absorption, Distribution, Metabolism, and Excretion (ADME) Studies of Biotherapeutics for Autoimmune and Inflammatory Conditions

Achieving Agility in Disaster Management

Pharmacokinetic–pharmacodynamic modelling of neutrophil response to G‐CSF in healthy subjects and patients with chemotherapy‐induced neutropenia

Clinically relevant cancer chemotherapy dose scheduling via mixed-integer optimization

Abstract 3364: Preclinical evaluation of BiTE®immune therapy targeting MUC17 or CLDN18.2 for gastric cancer

Quantification of Radiation Injury on Neutropenia and the Link between Absolute Neutrophil Count Time Course and Overall Survival in Nonhuman Primates Treated with G-CSF

Pharmacodynamic model for chemoradiotherapy-induced thrombocytopenia in mice

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