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β-Lactone natural products and derivatives inactivate homoserine transacetylase, a target for antimicrobial agents

Journal of antibiotics, 2011-07, Vol.64 (7), p.483-487

2011

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The Epoxy Group of Pramanicin Is Required for the Optimal Endothelium-Dependent Relaxation of Rat Aorta

Journal of Pharmacological Sciences, 2003, Vol.92(3), pp.203-208

2003

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Studies of structure and dynamics in a nominally symmetric twisted amide by NMR and electronic structure calculations

Canadian journal of chemistry, 2006-03, Vol.84 (3), p.421-428

2006

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Regioselectivity of glycoluril-directed Claisen condensations — A kinetic and mechanistic study of substituent effects in the nucleophilic acyl group

Canadian journal of chemistry, 2006-09, Vol.84 (9), p.1188-1196

2006

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Biomimetic decarboxylative condensation between malonate and acetate units attached to a glycoluril template

Canadian journal of chemistry, 2002-06, Vol.80 (6), p.601-607

2002

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Kinetics of glycoluril template-directed Claisen condensations Effect of thionation of the glycoluril

Canadian journal of chemistry, 2005-09, Vol.83 (9), p.1253-1260

2005

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Pramanicin, an antifungal agent, raises cytosolic Ca2+ and causes cell death in vascular endothelial cells

Vascular pharmacology, 2003, Vol.40 (1), p.35-42

2003

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Biosynthesis of ebelactone A: isotopic tracer, advanced precursor and genetic studies reveal a thioesterase-independent cyclization to give a polyketide β-lactone

Journal of antibiotics, 2013-07, Vol.66 (7), p.421-430

2013

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Vasorelaxant Effects of Pramanicin, an Anti-fungal Agent: Selective Action on Endothelial Cells

The Japanese Journal of Pharmacology, 2001, Vol.85(3), pp.234-240

2001

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Investigation of the Origin of C2 Units in Biosynthesis of Streptolydigin

Organic letters, 2004-10, Vol.6 (22), p.4033-4036

2004

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Biosynthesis of Streptolydigin: Origin of the Oxygen Atoms

Organic letters, 2006-11, Vol.8 (23), p.5329-5332

2006

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Twisted amides: X-ray crystallographic and theoretical study of two acylated glycolurils with aromatic substituents

Journal of molecular structure, 2003-11, Vol.660 (1), p.81-97

2003

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Twisted Amides: Synthesis and Structure of 1,6-Dipivaloyl-3,4,7,8- tetramethyl-2,5-dithioglycoluril

Organic letters, 2001-02, Vol.3 (4), p.495-498

2001

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Pramanicin, an antifungal agent, raises cytosolic Ca 2+ and causes cell death in vascular endothelial cells

Vascular pharmacology, 2003, Vol.40 (1), p.35-42

2003

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1-Acetyl-3,4-dimethyl-6-phenylacetyl-3a,4,6,6a-tetrahydroimidazo[4,5- d ]imidazole-2,5(1 H ,3 H )-dithione

Acta crystallographica. Section E, Structure reports online, 2007-02, Vol.63 (2), p.o613-o614

2007

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A Facile Preparation of Thioglycolurils from Glycolurils, and Regioselectivity in Thioglycoluril Template-Directed Crossed-Claisen Condensations

Journal of organic chemistry, 1997-12, Vol.62 (25), p.8834-8840

1997

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Synthesis and inhibitory action on HMG-CoA synthase of racemic and optically active oxetan-2-ones (β-Lactones)

Bioorganic & medicinal chemistry, 1998-08, Vol.6 (8), p.1255-1272

1998

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X-Ray crystal structure of 1,6-diacetyl-3,4,7,8-tetramethyl-2,5-dithioglycoluril, a highly twisted acetamide

Chemical communications (Cambridge, England), 1998-05 (10), p.1147-1148

Cow, Christopher N.

1998

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The Epoxy Group of Pramanicin Is Required for the Optimal Endothelium-Dependent Relaxation of Rat Aorta

Journal of pharmacological sciences, 2003, Vol.92 (3), p.203-208

2003

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The biosynthesis of pramanicin: origin of the carbon skeleton

Chemical communications (Cambridge, England), 1998 (2), p.273-274

1998

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The biosynthesis of pramanicin: intact incorporation of serine and absolute configuration of the antibiotic

Chemical communications (Cambridge, England), 1998-12 (23), p.2643-2644

1998

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Kinetics of glycoluril template-directed Claisen condensations and mechanistic implications

Canadian journal of chemistry, 2002-05, Vol.80 (5), p.517-527

2002

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The crystal structure of 3,4,7,8-tetramethylglycoluril

Canadian journal of chemistry, 1998-03, Vol.76 (3), p.301-306

1998

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Aristolochene biosynthesis and enzymatic cyclization of farnesyl pyrophosphate

Journal of the American Chemical Society, 1989-11, Vol.111 (24), p.8914-8916

1989

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Pentalenene biosynthesis and the enzymatic cyclization of farnesyl pyrophosphate: inversion at C-1 during 11-membered-ring formation

Journal of the American Chemical Society, 1988, Vol.110 (17), p.5922-5923

1988

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β-Lactone natural products and derivatives inactivate homoserine transacetylase, a target for antimicrobial agents

The Epoxy Group of Pramanicin Is Required for the Optimal Endothelium-Dependent Relaxation of Rat Aorta

Studies of structure and dynamics in a nominally symmetric twisted amide by NMR and electronic structure calculations

Regioselectivity of glycoluril-directed Claisen condensations — A kinetic and mechanistic study of substituent effects in the nucleophilic acyl group

Biomimetic decarboxylative condensation between malonate and acetate units attached to a glycoluril template

Kinetics of glycoluril template-directed Claisen condensations Effect of thionation of the glycoluril

Pramanicin, an antifungal agent, raises cytosolic Ca2+ and causes cell death in vascular endothelial cells

Biosynthesis of ebelactone A: isotopic tracer, advanced precursor and genetic studies reveal a thioesterase-independent cyclization to give a polyketide β-lactone

Vasorelaxant Effects of Pramanicin, an Anti-fungal Agent: Selective Action on Endothelial Cells

Investigation of the Origin of C2 Units in Biosynthesis of Streptolydigin

Biosynthesis of Streptolydigin: Origin of the Oxygen Atoms

Twisted amides: X-ray crystallographic and theoretical study of two acylated glycolurils with aromatic substituents

Twisted Amides: Synthesis and Structure of 1,6-Dipivaloyl-3,4,7,8- tetramethyl-2,5-dithioglycoluril

Pramanicin, an antifungal agent, raises cytosolic Ca 2+ and causes cell death in vascular endothelial cells

1-Acetyl-3,4-dimethyl-6-phenylacetyl-3a,4,6,6a-tetrahydroimidazo[4,5- d ]imidazole-2,5(1 H ,3 H )-dithione

A Facile Preparation of Thioglycolurils from Glycolurils, and Regioselectivity in Thioglycoluril Template-Directed Crossed-Claisen Condensations

Synthesis and inhibitory action on HMG-CoA synthase of racemic and optically active oxetan-2-ones (β-Lactones)

X-Ray crystal structure of 1,6-diacetyl-3,4,7,8-tetramethyl-2,5-dithioglycoluril, a highly twisted acetamide

The Epoxy Group of Pramanicin Is Required for the Optimal Endothelium-Dependent Relaxation of Rat Aorta

The biosynthesis of pramanicin: origin of the carbon skeleton

The biosynthesis of pramanicin: intact incorporation of serine and absolute configuration of the antibiotic

Kinetics of glycoluril template-directed Claisen condensations and mechanistic implications

The crystal structure of 3,4,7,8-tetramethylglycoluril

Aristolochene biosynthesis and enzymatic cyclization of farnesyl pyrophosphate

Pentalenene biosynthesis and the enzymatic cyclization of farnesyl pyrophosphate: inversion at C-1 during 11-membered-ring formation

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