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Alternative and aberrant splicing of MDM2 mRNA in human cancer

Cancer Cell, 2002-07, Vol.2 (1), p.9-15

2002

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MDM2 Splice Variants Predominantly Localize to the Nucleoplasm Mediated by a COOH-Terminal Nuclear Localization Signal

Molecular cancer research, 2007-04, Vol.5 (4), p.403-412

2007

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The MDM2-A Splice Variant of MDM2 Alters Transformation In vitro and the Tumor Spectrum in Both Arf- and p53-Null Models of Tumorigenesis

Molecular cancer research, 2009-06, Vol.7 (6), p.863-869

2009

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MDM2-A, a common Mdm2 splice variant, causes perinatal lethality, reduced longevity and enhanced senescence

Disease models & mechanisms, 2009-01, Vol.2 (1-2), p.47-55

2009

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Differential cooperation of oncogenes with p53 and Bax to induce apoptosis in rhabdomyosarcoma

Molecular cancer, 2006-11, Vol.5 (1), p.53-53, Article 53

2006

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MDM2 and its splice variant messenger RNAs: expression in tumors and down-regulation using antisense oligonucleotides

Molecular cancer research, 2004-01, Vol.2 (1), p.29-35

2004

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Selection for mutations in the cDNAs of transgenic mice upon expression of an embryonic lethal protein

Transgenic research, 2007-08, Vol.16 (4), p.527-530

2007

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p53-mediated regulation of expression of a rabbit liver carboxylesterase confers sensitivity to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11)

The Journal of pharmacology and experimental therapeutics, 2003-02, Vol.304 (2), p.699-705

2003

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MDM2 displays differential activities dependent upon the activation status of NFκB

Cancer biology & therapy, 2008-01, Vol.7 (1), p.38-44

2008

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Efficacy and toxicity of a virus-directed enzyme prodrug therapy purging method : Preclinical assessment and application to bone marrow samples from neuroblastoma patients

Cancer research (Chicago, Ill.), 2002-09, Vol.62 (17), p.5001-5007

2002

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Cytoplasmic Sequestration of an O6-Methylguanine-DNA Methyltransferase Enhancer Binding Protein in DNA Repair-Deficient Human Cells

Proceedings of the National Academy of Sciences - PNAS, 1997-04, Vol.94 (9), p.4348-4353

1997

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Novel mdm2 splice variants identified in pediatric rhabdomyosarcoma tumors and cell lines

Oncology research, 2001-01, Vol.12 (11-12), p.451

2001

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MDM2 does not influence p53-mediated sensitivity to DNA-damaging drugs

Molecular cancer therapeutics, 2002-10, Vol.1 (12), p.1097

2002

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Selective chemosensitization of rhabdomyosarcoma cell lines following wild-type p53 adenoviral transduction

Anti-cancer drugs, 2002-09, Vol.13 (8), p.881-889

2002

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Wild-type p53 induction mediated by replication-deficient adenoviral vectors

Cancer research (Chicago, Ill.), 1999-09, Vol.59 (17), p.4247-4251

1999

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Differences in epitope accessibility of p53 monoclonal antibodies suggest at least three conformations or states of protein binding of p53 protein in human tumor cell lines

Cell death and differentiation, 1998-08, Vol.5 (8), p.678-686

1998

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Use of the Ornithine Decarboxylase Promoter to Achieve N-MYC-Mediated Overexpression of a Rabbit Carboxylesterase to Sensitize Neuroblastoma Cells to CPT-11

Molecular therapy, 2000-05, Vol.1 (5), p.457-463

2000

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Epigenetic regulation of O 6-methylguanine-DNA methyltransferase gene expression by histone acetylation and methyl-CpG binding proteins

Molecular cancer therapeutics, 2005-01, Vol.4 (1), p.61-69

2005

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Construction of adenovirus for high level expression of small RNAs in mammalian cells: Application to a Bcl-2 ribozyme

Molecular biotechnology, 2000-06, Vol.15 (2), p.105-114

2000

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The MDM2-A splice variant of MDM2 alters transformation in vitro and the tumor spectrum in both Arf-null and p53-null models of tumorigenesis

Molecular cancer research, 2009-06, Vol.7 (6), p.863-869

2009

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Identification of a 59 bp enhancer located at the first exon/intron boundary of the human O6-methylguanine DNA methyltransferease gene

Nucleic acids research, 1994-11, Vol.22 (22), p.4614-4619

1994

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Sensitization of human tumor cells to CPT-11 via adenoviral-mediated delivery of a rabbit liver carboxylesterase

Cancer research (Chicago, Ill.), 2001-07, Vol.61 (13), p.5078-5082

2001

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Wild-type p53 can induce p21 and apoptosis in neuroblastoma cells but the DNA damage-induced G1 checkpoint function is attenuated

Clinical cancer research, 1999-12, Vol.5 (12), p.4199-4207

1999

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Characterization of the promoter region of the human O 6 -methylguanine-DNA methyltransferase gene

Nucleic acids research, 1991-11, Vol.19 (22), p.6163-6167

1991

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p53 mutation and MDM2 amplification frequency in pediatric rhabdomyosarcoma tumors and cell lines

Medical and pediatric oncology, 2000-08, Vol.35 (2), p.96-103

2000

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Alternative and aberrant splicing of MDM2 mRNA in human cancer

MDM2 Splice Variants Predominantly Localize to the Nucleoplasm Mediated by a COOH-Terminal Nuclear Localization Signal

The MDM2-A Splice Variant of MDM2 Alters Transformation In vitro and the Tumor Spectrum in Both Arf- and p53-Null Models of Tumorigenesis

MDM2-A, a common Mdm2 splice variant, causes perinatal lethality, reduced longevity and enhanced senescence

Differential cooperation of oncogenes with p53 and Bax to induce apoptosis in rhabdomyosarcoma

MDM2 and its splice variant messenger RNAs: expression in tumors and down-regulation using antisense oligonucleotides

Selection for mutations in the cDNAs of transgenic mice upon expression of an embryonic lethal protein

p53-mediated regulation of expression of a rabbit liver carboxylesterase confers sensitivity to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11)

MDM2 displays differential activities dependent upon the activation status of NFκB

Efficacy and toxicity of a virus-directed enzyme prodrug therapy purging method : Preclinical assessment and application to bone marrow samples from neuroblastoma patients

Cytoplasmic Sequestration of an O6-Methylguanine-DNA Methyltransferase Enhancer Binding Protein in DNA Repair-Deficient Human Cells

Novel mdm2 splice variants identified in pediatric rhabdomyosarcoma tumors and cell lines

MDM2 does not influence p53-mediated sensitivity to DNA-damaging drugs

Selective chemosensitization of rhabdomyosarcoma cell lines following wild-type p53 adenoviral transduction

Wild-type p53 induction mediated by replication-deficient adenoviral vectors

Differences in epitope accessibility of p53 monoclonal antibodies suggest at least three conformations or states of protein binding of p53 protein in human tumor cell lines

Use of the Ornithine Decarboxylase Promoter to Achieve N-MYC-Mediated Overexpression of a Rabbit Carboxylesterase to Sensitize Neuroblastoma Cells to CPT-11

Epigenetic regulation of O 6-methylguanine-DNA methyltransferase gene expression by histone acetylation and methyl-CpG binding proteins

Construction of adenovirus for high level expression of small RNAs in mammalian cells: Application to a Bcl-2 ribozyme

The MDM2-A splice variant of MDM2 alters transformation in vitro and the tumor spectrum in both Arf-null and p53-null models of tumorigenesis

Identification of a 59 bp enhancer located at the first exon/intron boundary of the human O6-methylguanine DNA methyltransferease gene

Sensitization of human tumor cells to CPT-11 via adenoviral-mediated delivery of a rabbit liver carboxylesterase

Wild-type p53 can induce p21 and apoptosis in neuroblastoma cells but the DNA damage-induced G1 checkpoint function is attenuated

Characterization of the promoter region of the human O 6 -methylguanine-DNA methyltransferase gene

p53 mutation and MDM2 amplification frequency in pediatric rhabdomyosarcoma tumors and cell lines

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