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Effect of pegylation on pharmaceuticals

Nature reviews. Drug discovery, 2003-03, Vol.2 (3), p.214-221

2003

Volltextzugriff (PDF)

Polyoxazoline: Chemistry, Properties, and Applications in Drug Delivery

Bioconjugate chemistry, 2011-05, Vol.22 (5), p.976-986

2011

Volltextzugriff (PDF)

Clinical development of a poly(2-oxazoline) (POZ) polymer therapeutic for the treatment of Parkinson’s disease – Proof of concept of POZ as a versatile polymer platform for drug development in multiple therapeutic indications

European polymer journal, 2017-03, Vol.88, p.524-552

2017

Volltextzugriff (PDF)

Tuning drug release from polyoxazoline-drug conjugates

European polymer journal, 2019-11, Vol.120, p.109241, Article 109241

2019

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Introduction and overview of peptide and protein pegylation

Advanced drug delivery reviews, 2002-06, Vol.54 (4), p.453-456

2002

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Delivery of PEGylated drugs from mucoadhesive formulations by pH-induced disruption of H-bonded complexes of PEG-drug with poly(acrylic acid)

Reactive & functional polymers, 2007-11, Vol.67 (11), p.1330-1337

2007

Volltextzugriff (PDF)

Pegylation: A novel process for modifying pharmacokinetics

Clinical pharmacokinetics, 2001, Vol.40 (7), p.539-551

2001

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Peptide and protein PEGylation III: advances in chemistry and clinical applications

Advanced drug delivery reviews, 2008-01, Vol.60 (1), p.1-2

2008

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Improvements in protein PEGylation: pegylated interferons for treatment of hepatitis C

Journal of controlled release, 2001-05, Vol.72 (1), p.217-224

2001

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Grafting Poly(ethylene glycol) Epoxide to Amino-Derivatized Quartz: Effect of Temperature and pH on Grafting Density

Analytical chemistry (Washington), 1996-11, Vol.68 (21), p.3751-3757

1996

Volltextzugriff (PDF)

Control of protein-ligand recognition using a stimuli-responsive polymer

Nature (London), 1995-11, Vol.378 (6556), p.472-474

1995

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Solubilization of enzymes in water-in-oil microemulsions and their rapid and efficient release through use of a pH-degradable surfactant

Biotechnology letters, 2007-05, Vol.29 (5), p.767-771

2007

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Preparation and Characterization of Poly(ethylene glycol) Vinyl Sulfone

Bioconjugate chemistry, 1996-05, Vol.7 (3), p.363-368

1996

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A Branched Monomethoxypoly(ethylene glycol) for Protein Modification

Bioconjugate chemistry, 1995-01, Vol.6 (1), p.62-69

1995

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Attachment of Degradable Poly(Ethylene Glycol) to Proteins has the Potential to Increase Therapeutic Efficacy

Journal of pharmaceutical sciences, 1998-11, Vol.87 (11), p.1440-1445

1998

Volltextzugriff (PDF)

A Solvolysis Model for 2-Chloro-2-methyladamantane Based on the Linear Solvation Energy Approach

Journal of organic chemistry, 2004-12, Vol.69 (25), p.8865-8873

2004

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Automated Particle Electrophoresis: Modeling and Control of Adverse Chamber Surface Properties

Analytical chemistry (Washington), 1998-06, Vol.70 (11), p.2268-2279

1998

Volltextzugriff (PDF)

Solvatochromism: a new method for polymer characterization

Macromolecules, 1990-10, Vol.23 (21), p.4557-4564

1990

Volltextzugriff (PDF)

Synthesis of methoxypoly(oxyethylene)propionic acid

Polymer bulletin (Berlin, Germany), 1999-08, Vol.43 (1), p.35-41

1999

Volltextzugriff (PDF)

Photoimmobilization of organophosphorus hydrolase within a PEG-based hydrogel

Biotechnology and bioengineering, 1999-12, Vol.65 (5), p.579-588

1999

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Effects of branching and molecular weight of surface-bound poly(ethylene oxide) on protein rejection

Journal of biomaterials science. Polymer ed., 1995-01, Vol.6 (2), p.123-132

1995

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Assessment of the Effects of Attaching an Enzyme to Glass by a Poly(ethylene glycol) Tether

Journal of bioactive and compatible polymers, 1989-07, Vol.4 (3), p.281-295

1989

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Novel polymer-polymer conjugates for recovery of lactic acid by aqueous two-phase extraction

Biotechnology and bioengineering, 1999, Vol.66 (4), p.211-218

1999

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Conjugates of stimuli-responsive polymers and biomolecules: Random and site-specific conjugates of temperature-sensitive polymers and proteins

Macromolecular symposia., 1997-06, Vol.118 (1), p.553-562

1997

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Sylvolytic Substitution in Simple Alkyl Systems

Progress in Physical Organic Chemistry, 1974, p.89-173

1974

Volltextzugriff (PDF)

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Effect of pegylation on pharmaceuticals

Polyoxazoline: Chemistry, Properties, and Applications in Drug Delivery

Clinical development of a poly(2-oxazoline) (POZ) polymer therapeutic for the treatment of Parkinson’s disease – Proof of concept of POZ as a versatile polymer platform for drug development in multiple therapeutic indications

Tuning drug release from polyoxazoline-drug conjugates

Introduction and overview of peptide and protein pegylation

Delivery of PEGylated drugs from mucoadhesive formulations by pH-induced disruption of H-bonded complexes of PEG-drug with poly(acrylic acid)

Pegylation: A novel process for modifying pharmacokinetics

Peptide and protein PEGylation III: advances in chemistry and clinical applications

Improvements in protein PEGylation: pegylated interferons for treatment of hepatitis C

Grafting Poly(ethylene glycol) Epoxide to Amino-Derivatized Quartz: Effect of Temperature and pH on Grafting Density

Control of protein-ligand recognition using a stimuli-responsive polymer

Solubilization of enzymes in water-in-oil microemulsions and their rapid and efficient release through use of a pH-degradable surfactant

Preparation and Characterization of Poly(ethylene glycol) Vinyl Sulfone

A Branched Monomethoxypoly(ethylene glycol) for Protein Modification

Attachment of Degradable Poly(Ethylene Glycol) to Proteins has the Potential to Increase Therapeutic Efficacy

A Solvolysis Model for 2-Chloro-2-methyladamantane Based on the Linear Solvation Energy Approach

Automated Particle Electrophoresis: Modeling and Control of Adverse Chamber Surface Properties

Solvatochromism: a new method for polymer characterization

Synthesis of methoxypoly(oxyethylene)propionic acid

Photoimmobilization of organophosphorus hydrolase within a PEG-based hydrogel

Effects of branching and molecular weight of surface-bound poly(ethylene oxide) on protein rejection

Assessment of the Effects of Attaching an Enzyme to Glass by a Poly(ethylene glycol) Tether

Novel polymer-polymer conjugates for recovery of lactic acid by aqueous two-phase extraction

Conjugates of stimuli-responsive polymers and biomolecules: Random and site-specific conjugates of temperature-sensitive polymers and proteins

Sylvolytic Substitution in Simple Alkyl Systems

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