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Neuroinflammatory markers associate with cognitive decline after major surgery: Findings of an explorative study

Annals of neurology, 2020-03, Vol.87 (3), p.370-382

2020

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TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis

The EMBO journal, 2013-01, Vol.32 (1), p.86-99

2013

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The immune response of the human brain to abdominal surgery

Annals of neurology, 2017-04, Vol.81 (4), p.572-582

2017

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Systemic HMGB1 Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats

Frontiers in immunology, 2016-10, Vol.7, p.441-441

2016

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A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug‐induced liver injury and postinjury inflammation in mice

Hepatology (Baltimore, Md.), 2016-11, Vol.64 (5), p.1699-1710

2016

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Therapeutic administration of etoposide coincides with reduced systemic HMGB1 levels in macrophage activation syndrome

Molecular medicine (Cambridge, Mass.), 2021-05, Vol.27 (1), p.48-48, Article 48

2021

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Neuroinflammation in Response to Intracerebral Injections of Different HMGB1 Redox Isoforms

Journal of innate immunity, 2018-01, Vol.10 (3), p.215-227

2018

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Disulfide and Fully Reduced HMGB1 Induce Different Macrophage Polarization and Migration Patterns

Biomolecules (Basel, Switzerland), 2021-05, Vol.11 (6), p.800

2021

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HMGB1 as a DNA-binding cytokine

Journal of leukocyte biology, 2002-12, Vol.72 (6), p.1084-1091

2002

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JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (8), p.3068-3073

2014

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Novel role of PKR in inflammasome activation and HMGB1 release

Nature (London), 2012-08, Vol.488 (7413), p.670-674

2012

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critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (26), p.11942-11947

2010

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Alarmin(g) news about danger: workshop on innate danger signals and HMGB1

EMBO reports, 2006-08, Vol.7 (8), p.774-778

2006

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Redox modifications of cysteine residues regulate the cytokine activity of HMGB1

Molecular medicine (Cambridge, Mass.), 2021-06, Vol.27 (1), p.58-58, Article 58

2021

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The role of HMGB1 in the pathogenesis of rheumatic disease

Biochimica et biophysica acta, 2010-01, Vol.1799 (1), p.141-148

2010

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Ligation of free HMGB1 to TLR2 in the absence of ligand is negatively regulated by the C-terminal tail domain

Molecular medicine (Cambridge, Mass.), 2018-05, Vol.24 (1), p.19-19, Article 19

2018

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Sex-dependent role of microglia in disulfide high mobility group box 1 protein-mediated mechanical hypersensitivity

Pain (Amsterdam), 2021-02, Vol.162 (2), p.446-458

2021

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Sex- and cell-dependent contribution of peripheral high mobility group box 1 and TLR4 in arthritis-induced pain

Pain (Amsterdam), 2021-02, Vol.162 (2), p.459-470

2021

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Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients--a prospective clinical study

Arthritis research & therapy, 2008-01, Vol.10 (2), p.R33-R33, Article R33

2008

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A systematic nomenclature for the redox states of high mobility group box (HMGB) proteins

Molecular medicine (Cambridge, Mass.), 2014-01, Vol.20 (1), p.135-137

2014

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The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation

Journal of leukocyte biology, 2009-09, Vol.86 (3), p.655-662

2009

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Pivotal Advance: Inhibition of HMGB1 nuclear translocation as a mechanism for the anti-rheumatic effects of gold sodium thiomalate

Journal of leukocyte biology, 2008-01, Vol.83 (1), p.31-38

2008

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High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease

Arthritis research & therapy, 2008-01, Vol.10 (3), p.209-209

2008

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Monoclonal anti-HMGB1 (high mobility group box chromosomal protein 1) antibody protection in two experimental arthritis models

Molecular medicine (Cambridge, Mass.), 2011-09, Vol.17 (9-10), p.1039-1044

2011

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HMGB1 levels are increased in patients with juvenile idiopathic arthritis, correlate with early onset of disease, and are independent of disease duration

Journal of rheumatology, 2013-09, Vol.40 (9), p.1604-1613

2013

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Neuroinflammatory markers associate with cognitive decline after major surgery: Findings of an explorative study

TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis

The immune response of the human brain to abdominal surgery

Systemic HMGB1 Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats

A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug‐induced liver injury and postinjury inflammation in mice

Therapeutic administration of etoposide coincides with reduced systemic HMGB1 levels in macrophage activation syndrome

Neuroinflammation in Response to Intracerebral Injections of Different HMGB1 Redox Isoforms

Disulfide and Fully Reduced HMGB1 Induce Different Macrophage Polarization and Migration Patterns

HMGB1 as a DNA-binding cytokine

JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation

Novel role of PKR in inflammasome activation and HMGB1 release

critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

Alarmin(g) news about danger: workshop on innate danger signals and HMGB1

Redox modifications of cysteine residues regulate the cytokine activity of HMGB1

The role of HMGB1 in the pathogenesis of rheumatic disease

Ligation of free HMGB1 to TLR2 in the absence of ligand is negatively regulated by the C-terminal tail domain

Sex-dependent role of microglia in disulfide high mobility group box 1 protein-mediated mechanical hypersensitivity

Sex- and cell-dependent contribution of peripheral high mobility group box 1 and TLR4 in arthritis-induced pain

Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients--a prospective clinical study

A systematic nomenclature for the redox states of high mobility group box (HMGB) proteins

The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation

Pivotal Advance: Inhibition of HMGB1 nuclear translocation as a mechanism for the anti-rheumatic effects of gold sodium thiomalate

High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease

Monoclonal anti-HMGB1 (high mobility group box chromosomal protein 1) antibody protection in two experimental arthritis models

HMGB1 levels are increased in patients with juvenile idiopathic arthritis, correlate with early onset of disease, and are independent of disease duration

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