UB Paderborn / Katalog / Suche / in CDI

Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (13), p.E1796-E1805

2016

Link zum Volltext

Verfügbarkeit prüfen

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

Nature medicine, 2016-10, Vol.22 (10), p.1108-1119

2016

Link zum Volltext

Verfügbarkeit prüfen

Acetyl‐coenzyme A carboxylase inhibition reduces de novo lipogenesis in overweight male subjects: A randomized, double‐blind, crossover study

Hepatology (Baltimore, Md.), 2017-08, Vol.66 (2), p.324-334

2017

Link zum Volltext

Verfügbarkeit prüfen

Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279

Journal of medicinal chemistry, 2023-08, Vol.66 (15), p.10473-10496

2023

Link zum Volltext

Verfügbarkeit prüfen

Potent and selective TYK2-JH1 inhibitors highly efficacious in rodent model of psoriasis

Bioorganic & medicinal chemistry letters, 2022-10, Vol.73, p.128891-128891, Article 128891

2022

Link zum Volltext

Verfügbarkeit prüfen

55 Exploring proximal biomarkers of CBL-B inhibition in human peripheral blood mononuclear cells

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A64-A64

2023

Link zum Volltext

Verfügbarkeit prüfen

864 Identification of a novel allosteric oral Cbl-b inhibitor that augmented T cell response and enhanced NK cell killing in vitro and in vivo

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A905-A905

2021

Link zum Volltext

Verfügbarkeit prüfen

Liver Selective Acetyl-CoA Carboxylase Inhibition Inhibits Hepatocellular Carcinoma in a Cirrhosis Model

Journal of the American College of Surgeons, 2014-09, Vol.219 (3), p.S23-S24

2014

Link zum Volltext

Verfügbarkeit prüfen

Design, Synthesis, and Evaluation of Naphthalene-Sulfonamide Antagonists of Human CCR8

Journal of medicinal chemistry, 2007-02, Vol.50 (3), p.566-584

2007

Link zum Volltext

Verfügbarkeit prüfen

Selective cell adhesion inhibitors: Barbituric acid based α4β7—MAdCAM inhibitors

Bioorganic & medicinal chemistry letters, 2008-04, Vol.18 (7), p.2509-2512

2008

Link zum Volltext

Verfügbarkeit prüfen

Selective cell adhesion inhibitors: Barbituric acid based alpha 4 beta 7 - MAdCAM inhibitors

Bioorganic & medicinal chemistry, 2008-04, Vol.18 (7), p.2509-2512

2008

Link zum Volltext

Verfügbarkeit prüfen

Synthesis of small and medium sized 2,2-disubstituted lactams via the “intramolecular” three component Ugi reaction

Tetrahedron letters, 1997-08, Vol.38 (32), p.5591-5594

Harriman, Geraldine C.B.

1997

Link zum Volltext

Verfügbarkeit prüfen

Accelerating drug discovery through tight integration of expert molecular design and predictive scoring

Current opinion in structural biology, 2017-04, Vol.43, p.38-44

2017

Link zum Volltext

Verfügbarkeit prüfen

Synthesis of 4-trifluoromethylpyrido[1,2- a]pyrimidin-2-ones utilizing activated alkynoates

Tetrahedron letters, 2003-04, Vol.44 (18), p.3659-3662

2003

Link zum Volltext

Verfügbarkeit prüfen

A Facile One-Flask Conversion of Aldehydes and Ketones to N-Sulfonyl Imines

Journal of organic chemistry, 1995-11, Vol.60 (22), p.7366-7368

1995

Link zum Volltext

Verfügbarkeit prüfen

Abstract LB337: Inhibition of the E3 ligase CBL-B enhances the effector function and proliferation of natural killer cells

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (8_Supplement), p.LB337-LB337

2023

Link zum Volltext

Verfügbarkeit prüfen

1354 CBL-B inhibition showed differentiated effects in a mixed lymphocyte reaction versus other immuno-oncology targeted approaches

Journal for immunotherapy of cancer, 2022, Vol.10 (Suppl 2), p.A1405-A1405

2022

Link zum Volltext

Verfügbarkeit prüfen

Synthesis, Conformational Analysis, and Biological Evaluation of Heteroaromatic Taxanes

Journal of organic chemistry, 1996-04, Vol.61 (8), p.2664-2676

1996

Link zum Volltext

Verfügbarkeit prüfen

Abstract 2679: Acetyl-CoA carboxylase inhibition by ND646 reduces fatty acid synthesis and inhibits cell proliferation in human non-small cell lung cancer cells

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.2679-2679

2014

Link zum Volltext

Verfügbarkeit prüfen

Synthesis of a Photoaffinity Taxol Analog and Its Use in Labeling Tubulin

Journal of medicinal chemistry, 1994-09, Vol.37 (18), p.2976-2980

1994

Link zum Volltext

Verfügbarkeit prüfen

Abstract 3781: Combination therapy with a liver selective acetyl-CoA carboxylase inhibitor ND-654 and sorafenib improves efficacy in the treatment of cirrhotic rats with hepatocellular carcinoma

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.3781-3781

2016

Link zum Volltext

Verfügbarkeit prüfen

Abstract 1048: Modulation of lipid metabolism through inhibition of acetyl-CoA carboxylase with ND-646 leads to potent inhibition of breast cancer cell growth in vitro and in vivo

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1048-1048

2016

Link zum Volltext

Verfügbarkeit prüfen

Abstract 598: A novel allosteric CBL-B inhibitor with differentiated immune enhancing activity in preclinical models

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.598-598

2022

Link zum Volltext

Verfügbarkeit prüfen

Abstract 4452: Liver selective acetyl-CoA carboxylase inhibition by ND-654 improves survival in cirrhotic rats with hepatocellular carcinoma

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.4452-4452

2015

Link zum Volltext

Verfügbarkeit prüfen

Menü

Weitere Dienste

Einstellungen

Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats

Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

Acetyl‐coenzyme A carboxylase inhibition reduces de novo lipogenesis in overweight male subjects: A randomized, double‐blind, crossover study

Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279

Potent and selective TYK2-JH1 inhibitors highly efficacious in rodent model of psoriasis

55 Exploring proximal biomarkers of CBL-B inhibition in human peripheral blood mononuclear cells

864 Identification of a novel allosteric oral Cbl-b inhibitor that augmented T cell response and enhanced NK cell killing in vitro and in vivo

Liver Selective Acetyl-CoA Carboxylase Inhibition Inhibits Hepatocellular Carcinoma in a Cirrhosis Model

Design, Synthesis, and Evaluation of Naphthalene-Sulfonamide Antagonists of Human CCR8

Selective cell adhesion inhibitors: Barbituric acid based α4β7—MAdCAM inhibitors

Selective cell adhesion inhibitors: Barbituric acid based alpha 4 beta 7 - MAdCAM inhibitors

Synthesis of small and medium sized 2,2-disubstituted lactams via the “intramolecular” three component Ugi reaction

Accelerating drug discovery through tight integration of expert molecular design and predictive scoring

Synthesis of 4-trifluoromethylpyrido[1,2- a]pyrimidin-2-ones utilizing activated alkynoates

A Facile One-Flask Conversion of Aldehydes and Ketones to N-Sulfonyl Imines

Abstract LB337: Inhibition of the E3 ligase CBL-B enhances the effector function and proliferation of natural killer cells

1354 CBL-B inhibition showed differentiated effects in a mixed lymphocyte reaction versus other immuno-oncology targeted approaches

Synthesis, Conformational Analysis, and Biological Evaluation of Heteroaromatic Taxanes

Abstract 2679: Acetyl-CoA carboxylase inhibition by ND646 reduces fatty acid synthesis and inhibits cell proliferation in human non-small cell lung cancer cells

Synthesis of a Photoaffinity Taxol Analog and Its Use in Labeling Tubulin

Abstract 3781: Combination therapy with a liver selective acetyl-CoA carboxylase inhibitor ND-654 and sorafenib improves efficacy in the treatment of cirrhotic rats with hepatocellular carcinoma

Abstract 1048: Modulation of lipid metabolism through inhibition of acetyl-CoA carboxylase with ND-646 leads to potent inhibition of breast cancer cell growth in vitro and in vivo

Abstract 598: A novel allosteric CBL-B inhibitor with differentiated immune enhancing activity in preclinical models

Abstract 4452: Liver selective acetyl-CoA carboxylase inhibition by ND-654 improves survival in cirrhotic rats with hepatocellular carcinoma

Suchergebnisse filtern