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Electrolytic Macrocyclizations: Scalable Synthesis of a Diazonamide-Based Drug Development Candidate

Angewandte Chemie (International ed.), 2015-04, Vol.54 (16), p.4818-4822

International ed. in English, 2015

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Exploring the Boundaries of “Practical”: De Novo Syntheses of Complex Natural Product-Based Drug Candidates

Chemical reviews, 2017-09, Vol.117 (18), p.11994-12051

2017

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Cascade Synthesis of Fluorinated Spiroheterocyclic Scaffolding for Peptidic Macrobicycles

Journal of the American Chemical Society, 2023-07, Vol.145 (29), p.15888-15895

2023

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Template-constrained macrocyclic peptides prepared from native, unprotected precursors

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (40), p.15861-15861

2013

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Anomalous Chromophore Disruption Enables an Eight-Step Synthesis and Stereochemical Reassignment of (+)-Marineosin A

Journal of the American Chemical Society, 2019-02, Vol.141 (6), p.2274-2278

2019

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Cascading Auto-oxidative Biproline Guanylations Form Optically Active Dispacamide Dimers and Permit an Eight-Step Synthesis of (−)-Ageliferin

Journal of organic chemistry, 2018-07, Vol.83 (13), p.7231-7238

2018

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In Search of Small Molecules That Selectively Inhibit MBOAT4

Molecules (Basel, Switzerland), 2021-12, Vol.26 (24), p.7599

2021

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Large ring-forming alkylations provide facile access to composite macrocycles

Chemical science (Cambridge), 2015-04, Vol.6 (4), p.2219-2223

2015

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Synthetic (±)-Axinellamines Deficient in Halogen

Angewandte Chemie (International ed.), 2012-04, Vol.51 (18), p.4340-4343

International ed. in English, 2012

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Diazonamide Toxins Reveal an Unexpected Function for Ornithine δ-Amino Transferase in Mitotic Cell Division

Proceedings of the National Academy of Sciences - PNAS, 2007-02, Vol.104 (7), p.2068-2073

2007

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Unconventional Fragment Usage Enables a Concise Total Synthesis of (−)-Callyspongiolide

Journal of the American Chemical Society, 2018-01, Vol.140 (4), p.1280-1284

2018

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Exploring Symmetry-Based Logic for a Synthesis of Palau’amine

Journal of organic chemistry, 2009-08, Vol.74 (16), p.5909-5919

2009

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Origin of Octafluorocyclopentene Polyelectrophilicity

Journal of the American Chemical Society, 2024-02, Vol.146 (8), p.5375-5382

2024

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Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity

Proceedings of the National Academy of Sciences - PNAS, 2007-02, Vol.104 (7), p.2074-2079

2007

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Asymmetric Organocatalysis Enables Rapid Assembly of Portimine Precursor Chains

Organic letters, 2022-04, Vol.24 (14), p.2607-2612

2022

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Spirocycloisomerization of Tethered Alkylidene Glycocyamidines: Synthesis of a Base Template Common to the Palau'amine Family of Alkaloids

Angewandte Chemie (International ed.), 2005-01, Vol.44 (5), p.765-769

2005

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Syntheses of Atypically Fluorinated Peptidyl Macrocycles through Sequential Vinylic Substitutions

Angewandte Chemie International Edition, 2020-01, Vol.59 (2), p.674-678

International ed. in English, 2020

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Computational generation of an annotated gigalibrary of synthesizable, composite peptidic macrocycles

Proceedings of the National Academy of Sciences - PNAS, 2020-10, Vol.117 (40), p.24679-24690

2020

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Modular Access to Complex Prodiginines: Total Synthesis of (+)-Roseophilin via its 2‑Azafulvene Prototropisomer

Journal of the American Chemical Society, 2013-03, Vol.135 (10), p.3788-3791

2013

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A Small Molecule Smac Mimic Potentiates TRAIL- and TNFα-Mediated Cell Death

Science (American Association for the Advancement of Science), 2004-09, Vol.305 (5689), p.1471-1474

2004

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Callyspongiolide Is a Potent Inhibitor of the Vacuolar ATPase

Journal of natural products (Washington, D.C.), 2020-11, Vol.83 (11), p.3381-3386

2020

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Photorearrangement of [8]-2,6-Pyridinophane N‑Oxide

Journal of the American Chemical Society, 2020-12, Vol.142 (49), p.20717-20724

2020

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Template-induced macrocycle diversity through large ring-forming alkylations of tryptophan

Tetrahedron, 2013-09, Vol.69 (36), p.7683-7691

2013

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A Missense Mutation in Caenorhabditis elegans Prohibitin 2 Confers an Atypical Multidrug Resistance

Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (42), p.15523-15528

2006

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Assembly of Complex Macrocycles by Incrementally Amalgamating Unprotected Peptides with a Designed Four-Armed Insert

Journal of organic chemistry, 2018-03, Vol.83 (6), p.3090-3108

2018

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Electrolytic Macrocyclizations: Scalable Synthesis of a Diazonamide-Based Drug Development Candidate

Exploring the Boundaries of “Practical”: De Novo Syntheses of Complex Natural Product-Based Drug Candidates

Cascade Synthesis of Fluorinated Spiroheterocyclic Scaffolding for Peptidic Macrobicycles

Template-constrained macrocyclic peptides prepared from native, unprotected precursors

Anomalous Chromophore Disruption Enables an Eight-Step Synthesis and Stereochemical Reassignment of (+)-Marineosin A

Cascading Auto-oxidative Biproline Guanylations Form Optically Active Dispacamide Dimers and Permit an Eight-Step Synthesis of (−)-Ageliferin

In Search of Small Molecules That Selectively Inhibit MBOAT4

Large ring-forming alkylations provide facile access to composite macrocycles

Synthetic (±)-Axinellamines Deficient in Halogen

Diazonamide Toxins Reveal an Unexpected Function for Ornithine δ-Amino Transferase in Mitotic Cell Division

Unconventional Fragment Usage Enables a Concise Total Synthesis of (−)-Callyspongiolide

Exploring Symmetry-Based Logic for a Synthesis of Palau’amine

Origin of Octafluorocyclopentene Polyelectrophilicity

Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity

Asymmetric Organocatalysis Enables Rapid Assembly of Portimine Precursor Chains

Spirocycloisomerization of Tethered Alkylidene Glycocyamidines: Synthesis of a Base Template Common to the Palau'amine Family of Alkaloids

Syntheses of Atypically Fluorinated Peptidyl Macrocycles through Sequential Vinylic Substitutions

Computational generation of an annotated gigalibrary of synthesizable, composite peptidic macrocycles

Modular Access to Complex Prodiginines: Total Synthesis of (+)-Roseophilin via its 2‑Azafulvene Prototropisomer

A Small Molecule Smac Mimic Potentiates TRAIL- and TNFα-Mediated Cell Death

Callyspongiolide Is a Potent Inhibitor of the Vacuolar ATPase

Photorearrangement of [8]-2,6-Pyridinophane N‑Oxide

Template-induced macrocycle diversity through large ring-forming alkylations of tryptophan

A Missense Mutation in Caenorhabditis elegans Prohibitin 2 Confers an Atypical Multidrug Resistance

Assembly of Complex Macrocycles by Incrementally Amalgamating Unprotected Peptides with a Designed Four-Armed Insert

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