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Cardioprotection Resulting from Glucagon-Like Peptide-1 Administration Involves Shifting Metabolic Substrate Utilization to Increase Energy Efficiency in the Rat Heart

PloS one, 2015-06, Vol.10 (6), p.e0130894-e0130894

2015

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Albiglutide, a long lasting glucagon-like peptide-1 analog, protects the rat heart against ischemia/reperfusion injury: evidence for improving cardiac metabolic efficiency

PloS one, 2011-08, Vol.6 (8), p.e23570

2011

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In vitro, antithrombotic and bleeding time studies of BMS-654457, a small-molecule, reversible and direct inhibitor of factor XIa

Journal of thrombosis and thrombolysis, 2015-11, Vol.40 (4), p.416-423

2015

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Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase

Bioorganic & medicinal chemistry letters, 2013-06, Vol.23 (12), p.3584-3588

2013

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Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (1), p.27-30

2009

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Tetrahydroquinoline Derivatives as Potent and Selective Factor XIa Inhibitors

Journal of medicinal chemistry, 2014-02, Vol.57 (3), p.955-969

2014

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Targeting enzyme inhibitors in drug discovery

Expert opinion on therapeutic targets, 2007-07, Vol.11 (7), p.967-978

2007

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NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation

Journal of enzyme inhibition and medicinal chemistry, 2013-02, Vol.28 (1), p.95-104

2013

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Discovery of renin inhibitors containing a simple aspartate binding moiety that imparts reduced P450 inhibition

Bioorganic & medicinal chemistry letters, 2017-11, Vol.27 (21), p.4838-4843

2017

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Chronic Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Activity Decreases Hypertension, Insulin Resistance, and Hypertriglyceridemia in Metabolic Syndrome

BioMed research international, 2013-01, Vol.2013 (2013), p.1-10

2013

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Multifaceted Roles of Lys166 of Ribulose-bisphosphate Carboxylase/Oxygenase As Discerned by Product Analysis and Chemical Rescue of Site-Directed Mutants

Biochemistry (Easton), 2002-01, Vol.41 (4), p.1390-1397

2002

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Comparison of non-digitalis binding properties of digoxin-specific Fabs using direct binding methods

Journal of immunological methods, 2008-07, Vol.336 (2), p.235-241

2008

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Expression, purification, and characterization of human and rat acetyl coenzyme A carboxylase (ACC) isozymes

Protein expression and purification, 2007-01, Vol.51 (1), p.11-21

2007

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Mutagenesis and Mechanism-Based Inhibition of Streptococcus pyogenes Glu-tRNAGln Amidotransferase Implicate a Serine-Based Glutaminase Site

Biochemistry (Easton), 2002-05, Vol.41 (20), p.6398-6407

2002

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Mechanistic Studies of Reaction Coupling in Glu-tRNAGln Amidotransferase

Biochemistry (Easton), 2001-05, Vol.40 (21), p.6450-6457

2001

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Expression, purification, and characterization of human and rat acetyl cfenzyme A carboxylase (ACC) isozymes

Protein expression and purification, 2007, Vol.51 (1), p.11-21

2007

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Role of Lys100 in Human Dihydroorotate Dehydrogenase: Mutagenesis Studies and Chemical Rescue by External Amines

Biochemistry (Easton), 2000-07, Vol.39 (27), p.7990-7997

2000

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Chemical Rescue by Exogenous Amines of a Site-Directed Mutant of Ribulose 1,5-Bisphosphate Carboxylase/Oxygenase That Lacks a Key Lysyl Residue

Biochemistry (Easton), 1994-05, Vol.33 (18), p.5553-5561

1994

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Facilitation of the Terminal Proton Transfer Reaction of Ribulose 1,5-Bisphosphate Carboxylase/Oxygenase by Active-Site Lys166

Biochemistry (Easton), 1996-11, Vol.35 (44), p.13865-13870

1996

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Multiple catalytic roles of His 287 of Rhodospirillum rubrum ribulose 1,5‐bisphosphate carboxylase/oxygenase

Protein science, 1998-03, Vol.7 (3), p.730-738

1998

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Structure, Function, Regulation, and Assembly of D-Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase

Annual review of biochemistry, 1994, Vol.63 (1), p.197-232

1994

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Mutagenesis and Mechanism-Based Inhibition of Streptococcus pyogenes Glu−tRNAGln Amidotransferase Implicate a Serine-Based Glutaminase Site

Biochemistry (Easton), 2002-09, Vol.41 (38), p.11516-11516

2002

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Glutamyl-γ-boronate inhibitors of bacterial Glu-tRNAGln amidotransferase

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (18), p.2561-2564

2001

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Suppression of 11beta-hydroxysteroid dehydrogenase type 1 activity diminish insulin resistance and hypertriglyceridemia in metabolic syndrome

Cell biology international, 2010-08, Vol.34 (8), p.S30-S30

2010

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Cardioprotection Resulting from Glucagon-Like Peptide-1 Administration Involves Shifting Metabolic Substrate Utilization to Increase Energy Efficiency in the Rat Heart

Albiglutide, a long lasting glucagon-like peptide-1 analog, protects the rat heart against ischemia/reperfusion injury: evidence for improving cardiac metabolic efficiency

In vitro, antithrombotic and bleeding time studies of BMS-654457, a small-molecule, reversible and direct inhibitor of factor XIa

Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase

Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors

Tetrahydroquinoline Derivatives as Potent and Selective Factor XIa Inhibitors

In Vivo Half-Life Extension of BMP1/TLL Metalloproteinase Inhibitors Using Small-Molecule Human Serum Albumin Binders

Targeting enzyme inhibitors in drug discovery

NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation

Discovery of renin inhibitors containing a simple aspartate binding moiety that imparts reduced P450 inhibition

Chronic Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Activity Decreases Hypertension, Insulin Resistance, and Hypertriglyceridemia in Metabolic Syndrome

Multifaceted Roles of Lys166 of Ribulose-bisphosphate Carboxylase/Oxygenase As Discerned by Product Analysis and Chemical Rescue of Site-Directed Mutants

Comparison of non-digitalis binding properties of digoxin-specific Fabs using direct binding methods

Expression, purification, and characterization of human and rat acetyl coenzyme A carboxylase (ACC) isozymes

Mutagenesis and Mechanism-Based Inhibition of Streptococcus pyogenes Glu-tRNAGln Amidotransferase Implicate a Serine-Based Glutaminase Site

Mechanistic Studies of Reaction Coupling in Glu-tRNAGln Amidotransferase

Expression, purification, and characterization of human and rat acetyl cfenzyme A carboxylase (ACC) isozymes

Role of Lys100 in Human Dihydroorotate Dehydrogenase: Mutagenesis Studies and Chemical Rescue by External Amines

Chemical Rescue by Exogenous Amines of a Site-Directed Mutant of Ribulose 1,5-Bisphosphate Carboxylase/Oxygenase That Lacks a Key Lysyl Residue

Facilitation of the Terminal Proton Transfer Reaction of Ribulose 1,5-Bisphosphate Carboxylase/Oxygenase by Active-Site Lys166

Multiple catalytic roles of His 287 of Rhodospirillum rubrum ribulose 1,5‐bisphosphate carboxylase/oxygenase

Structure, Function, Regulation, and Assembly of D-Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase

Mutagenesis and Mechanism-Based Inhibition of Streptococcus pyogenes Glu−tRNAGln Amidotransferase Implicate a Serine-Based Glutaminase Site

Glutamyl-γ-boronate inhibitors of bacterial Glu-tRNAGln amidotransferase

Suppression of 11beta-hydroxysteroid dehydrogenase type 1 activity diminish insulin resistance and hypertriglyceridemia in metabolic syndrome

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