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Analysis of Human Cytochrome P450 3A4 Cooperativity: Construction and Characterization of a Site-Directed Mutant that Displays Hyperbolic Steroid Hydroxylation Kinetics

Proceedings of the National Academy of Sciences - PNAS, 1998-06, Vol.95 (12), p.6636-6641

1998

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Arabidopsis mutants deficient in T-DNA integration

Proceedings of the National Academy of Sciences - PNAS, 1995-12, Vol.92 (25), p.11786-11790

1995

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Radiation-sensitive mutants of Arabidopsis thaliana

Genetics (Austin), 1995-06, Vol.140 (2), p.725-732

1995

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Isolation of uvh1, an Arabidopsis mutant hypersensitive to ultraviolet light and ionizing radiation

The Plant cell, 1994-02, Vol.6 (2), p.227-235

1994

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Alanine-scanning mutagenesis of a putative substrate recognition site in human cytochrome P450 3A4. Role of residues 210 and 211 in flavonoid activation and substrate specificity

The Journal of biological chemistry, 1997-02, Vol.272 (9), p.5396-5402

1997

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Dual role of human cytochrome P450 3A4 residue Phe-304 in substrate specificity and cooperativity

The Journal of pharmacology and experimental therapeutics, 2000-05, Vol.293 (2), p.585

2000

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Characterization of the progesterone 21-hydroxylase activity of canine cytochrome P450 PBD-2/P450 2B11 through reconstitution, heterologous expression, and site-directed mutagenesis

Drug metabolism and disposition, 1995-07, Vol.23 (7), p.702

1995

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Analysis of Four Residues within Substrate Recognition Site 4 of Human Cytochrome P450 3A4: Role in Steroid Hydroxylase Activity and α-Naphthoflavone Stimulation

Archives of biochemistry and biophysics, 1998-02, Vol.350 (2), p.223-232

1998

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Identification of High Affinity Binding Sites for LexA which Define New DNA Damage-inducible Genes in Escherichia coli

Journal of molecular biology, 1994-08, Vol.241 (4), p.507-523

1994

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Escherichia coli expression and substrate specificities of canine cytochrome P450 3A12 and rabbit cytochrome P450 3A6

The Journal of pharmacology and experimental therapeutics, 1996-08, Vol.278 (2), p.957

1996

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Isolation, heterologous expression and functional characterization of a novel cytochrome P450 3A enzyme from a canine liver cDNA library

The Journal of pharmacology and experimental therapeutics, 1997-12, Vol.283 (3), p.1425

1997

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Use of the steroid derivative RPR 106541 in combination with site-directed mutagenesis for enhanced cytochrome P-450 3A4 structure/function analysis

The Journal of pharmacology and experimental therapeutics, 1999-08, Vol.290 (2), p.594

1999

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Mutagenesis Study of Asp-290 in Cytochrome P450 2B11 Using a Fusion Protein with Rat NADPH-Cytochrome P450 Reductase

Archives of biochemistry and biophysics, 1996-02, Vol.326 (1), p.85-92

1996

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Structural Determinants of Progesterone Hydroxylation by Cytochrome P450 2B5: The Role of Nonsubstrate Recognition Site Residues

Archives of biochemistry and biophysics, 1998-02, Vol.350 (2), p.333-339

1998

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Use of chimeric enzymes and site-directed mutagenesis for identification of three key residues responsible for differences in steroid hydroxylation between canine cytochromes P-450 3A12 and 3A26

Molecular pharmacology, 1999-02, Vol.55 (2), p.241-247

1999

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Functional interaction between amino-acid residues 242 and 290 in cytochromes P-450 2B1 and 2B11

Biochimica et biophysica acta, 1997-04, Vol.1338 (2), p.259-266

1997

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2,2‘,3,3‘,6,6‘-Hexachlorobiphenyl Hydroxylation by Active Site Mutants of Cytochrome P450 2B1 and 2B11

Chemical research in toxicology, 1999-08, Vol.12 (8), p.690-699

1999

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Sound distribution at low frequencies in a rectangular enclosure

Journal of physics. D, Applied physics, 1968-02, Vol.1 (2), p.263-264, Article 418

1968

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The assignment of safety systems addressing workplace hazards

Process safety progress, 1998-12, Vol.17 (4), p.233-237

1998

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The velocity of sound in air, nitrogen and argon

British journal of applied physics, 1963-02, Vol.14 (2), p.102-106

1963

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Infections of Scribner and Brescia Arteriovenous Shunts

BMJ, 1971-08, Vol.3 (5771), p.408-409

1971

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TOWARD THE EFFECTIVE USE OF THE PSYCHOLOGICAL CONSULTATION

The American journal of psychiatry, 1958-09, Vol.115 (3), p.228-231

1958

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A frequency modulation technique for the measurement of internal friction

Journal of scientific instruments, 1962-12, Vol.39 (12), p.598-599

1962

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Bacteriological Studies of the Modified Kiil Dialyser

BMJ, 1970-07, Vol.3 (5715), p.135-137

1970

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MASCULINE INADEQUACY AND COMPENSATORY DEVELOPMENT OF PHYSIQUE

Journal of personality, 1951-03, Vol.19 (3), p.312-323

Harlow, Robert G.

1951

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Analysis of Human Cytochrome P450 3A4 Cooperativity: Construction and Characterization of a Site-Directed Mutant that Displays Hyperbolic Steroid Hydroxylation Kinetics

Arabidopsis mutants deficient in T-DNA integration

Radiation-sensitive mutants of Arabidopsis thaliana

Isolation of uvh1, an Arabidopsis mutant hypersensitive to ultraviolet light and ionizing radiation

Alanine-scanning mutagenesis of a putative substrate recognition site in human cytochrome P450 3A4. Role of residues 210 and 211 in flavonoid activation and substrate specificity

Dual role of human cytochrome P450 3A4 residue Phe-304 in substrate specificity and cooperativity

Characterization of the progesterone 21-hydroxylase activity of canine cytochrome P450 PBD-2/P450 2B11 through reconstitution, heterologous expression, and site-directed mutagenesis

Analysis of Four Residues within Substrate Recognition Site 4 of Human Cytochrome P450 3A4: Role in Steroid Hydroxylase Activity and α-Naphthoflavone Stimulation

Identification of High Affinity Binding Sites for LexA which Define New DNA Damage-inducible Genes in Escherichia coli

Escherichia coli expression and substrate specificities of canine cytochrome P450 3A12 and rabbit cytochrome P450 3A6

Isolation, heterologous expression and functional characterization of a novel cytochrome P450 3A enzyme from a canine liver cDNA library

Use of the steroid derivative RPR 106541 in combination with site-directed mutagenesis for enhanced cytochrome P-450 3A4 structure/function analysis

Mutagenesis Study of Asp-290 in Cytochrome P450 2B11 Using a Fusion Protein with Rat NADPH-Cytochrome P450 Reductase

Structural Determinants of Progesterone Hydroxylation by Cytochrome P450 2B5: The Role of Nonsubstrate Recognition Site Residues

Use of chimeric enzymes and site-directed mutagenesis for identification of three key residues responsible for differences in steroid hydroxylation between canine cytochromes P-450 3A12 and 3A26

Functional interaction between amino-acid residues 242 and 290 in cytochromes P-450 2B1 and 2B11

2,2‘,3,3‘,6,6‘-Hexachlorobiphenyl Hydroxylation by Active Site Mutants of Cytochrome P450 2B1 and 2B11

Sound distribution at low frequencies in a rectangular enclosure

The assignment of safety systems addressing workplace hazards

The velocity of sound in air, nitrogen and argon

Infections of Scribner and Brescia Arteriovenous Shunts

TOWARD THE EFFECTIVE USE OF THE PSYCHOLOGICAL CONSULTATION

A frequency modulation technique for the measurement of internal friction

Bacteriological Studies of the Modified Kiil Dialyser

MASCULINE INADEQUACY AND COMPENSATORY DEVELOPMENT OF PHYSIQUE

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