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Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

Nature (London), 1994-09, Vol.371 (6493), p.168-170

1994

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Novel method to specifically determine the structures of non-N297 glycans in IgGs

Glycobiology (Oxford), 2023-06, Vol.33 (5), p.364-368

2023

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Structural Characterization of a Soluble Amyloid β-Peptide Oligomer

Biochemistry (Easton), 2009-03, Vol.48 (9), p.1870-1877

2009

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Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195

ACS medicinal chemistry letters, 2013-02, Vol.4 (2), p.211-215

2013

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Iniparib Nonselectively Modifies Cysteine-Containing Proteins in Tumor Cells and Is Not a Bona Fide PARP Inhibitor

Clinical cancer research, 2012-01, Vol.18 (2), p.510-523

2012

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Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design

mAbs, 2011-09, Vol.3 (5), p.487-494

2011

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A potent erythropoietin-mimicking human antibody interacts through a novel binding site

Blood, 2007-10, Vol.110 (7), p.2408-2413

2007

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Structure and ligand recognition of the phosphotyrosine binding domain of Shc

Nature (London), 1995-12, Vol.378 (6557), p.584-592

1995

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NMR Structure and Mutagenesis of the N-Terminal Dbl Homology Domain of the Nucleotide Exchange Factor Trio

Cell, 1998-10, Vol.95 (2), p.269-277

1998

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Structure of Bcl-x-Bak peptide complex: recognition between regulators of apoptosis

Science (American Association for the Advancement of Science), 1997-02, Vol.275 (5302), p.983

1997

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Structural Characterization of the Interaction between a Pleckstrin Homology Domain and Phosphatidylinositol 4,5-Bisphosphate

Biochemistry (Easton), 1995-08, Vol.34 (31), p.9859-9864

1995

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X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

Nature (London), 1996-05, Vol.381 (6580), p.335-341

1996

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Structure of MurF from Streptococcus pneumoniae co‐crystallized with a small molecule inhibitor exhibits interdomain closure

Protein science, 2005-12, Vol.14 (12), p.3039-3047

2005

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Recombinant kringle 5 from plasminogen antagonises hepatocyte growth factor-mediated signalling

European journal of cancer (1990), 2010-03, Vol.46 (5), p.966-973

2010

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Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization

Journal of medicinal chemistry, 2004-03, Vol.47 (7), p.1709-1718

2004

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Synthesis and evaluation of inhibitors of cytochrome P450 3A (CYP3A) for pharmacokinetic enhancement of drugs

Bioorganic & medicinal chemistry letters, 2009-09, Vol.19 (18), p.5444-5448

2009

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On-column ligand exchange for structure-based drug design: a case study with human 11[beta]-hydroxysteroid dehydrogenase type 1

Acta crystallographica. Section F, Structural biology communications, 2013-11, Vol.68 (5), p.601

2013

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Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivo

Molecular and Cellular Biology, 1997-09, Vol.17 (9), p.5540-5549

1997

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On-column ligand exchange for structure-based drug design: a case study with human 11β-hydroxysteroid dehydrogenase type 1

Acta crystallographica. Section F, Structural biology and crystallization communications, 2012-05, Vol.68 (5), p.601-605

2012

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P2-483: Biophysical characterization of soluble amyloid-β peptide oligomers

Alzheimer's & dementia, 2008-07, Vol.4 (4), p.T516-T516

2008

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Abstract 2783: Empowering therapeutic monoclonal antibodies with IFN-alpha for cancer immunotherapy

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2783-2783

2018

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Design and characterization of an engineered gp41 protein from human immunodeficiency virus-1 as a tool for drug discovery

Journal of computer-aided molecular design, 2007-01, Vol.21 (1-3), p.121-130

2007

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A highly potent and selective farnesyltransferase inhibitor ABT-100 in preclinical studies

Anti-cancer drugs, 2005-11, Vol.16 (10), p.1059-1069

2005

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Observations of Xyleborus affinis Eichhoff (Coleoptera:Curculionidae:Scolytinae) in Central Michigan

Great Lakes entomologist, 2017-04, Vol.48 (3)

2017

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NMR Studies of the Anti-Apoptotic Protein Bcl-xL in Micelles

Biochemistry (Easton), 2000-09, Vol.39 (36), p.11024-11033

2000

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Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

Novel method to specifically determine the structures of non-N297 glycans in IgGs

Structural Characterization of a Soluble Amyloid β-Peptide Oligomer

Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195

Iniparib Nonselectively Modifies Cysteine-Containing Proteins in Tumor Cells and Is Not a Bona Fide PARP Inhibitor

Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design

A potent erythropoietin-mimicking human antibody interacts through a novel binding site

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

NMR Structure and Mutagenesis of the N-Terminal Dbl Homology Domain of the Nucleotide Exchange Factor Trio

Structure of Bcl-x-Bak peptide complex: recognition between regulators of apoptosis

Structural Characterization of the Interaction between a Pleckstrin Homology Domain and Phosphatidylinositol 4,5-Bisphosphate

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

Structure of MurF from Streptococcus pneumoniae co‐crystallized with a small molecule inhibitor exhibits interdomain closure

Recombinant kringle 5 from plasminogen antagonises hepatocyte growth factor-mediated signalling

Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization

Synthesis and evaluation of inhibitors of cytochrome P450 3A (CYP3A) for pharmacokinetic enhancement of drugs

On-column ligand exchange for structure-based drug design: a case study with human 11[beta]-hydroxysteroid dehydrogenase type 1

Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivo

On-column ligand exchange for structure-based drug design: a case study with human 11β-hydroxysteroid dehydrogenase type 1

P2-483: Biophysical characterization of soluble amyloid-β peptide oligomers

Abstract 2783: Empowering therapeutic monoclonal antibodies with IFN-alpha for cancer immunotherapy

Design and characterization of an engineered gp41 protein from human immunodeficiency virus-1 as a tool for drug discovery

A highly potent and selective farnesyltransferase inhibitor ABT-100 in preclinical studies

Observations of Xyleborus affinis Eichhoff (Coleoptera:Curculionidae:Scolytinae) in Central Michigan

NMR Studies of the Anti-Apoptotic Protein Bcl-xL in Micelles

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