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The immunogenicity of humanized and fully human antibodies: Residual immunogenicity resides in the CDR regions

mAbs, 2010-05, Vol.2 (3), p.256-265

2010

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A β-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy

Molecular cancer therapeutics, 2005-11, Vol.4 (11), p.1791-1800

2005

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Design, creation and in vitro testing of a reduced immunogenicity humanized anti-CD25 monoclonal antibody that retains functional activity

Protein engineering, design and selection, 2019-12, Vol.32 (12), p.543-554

2019

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Murinization and H Chain Isotype Matching of the Anti-GITR Antibody DTA-1 Reduces Immunogenicity-Mediated Anaphylaxis in C57BL/6 Mice

The Journal of immunology (1950), 2017-06, Vol.198 (11), p.4502-4512

2017

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Antigen-specific human antibodies from mice comprising four distinct genetic modifications

Nature (London), 1994-04, Vol.368 (6474), p.856-859

1994

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Elimination of an immunodominant CD4+ T cell epitope in human IFN-beta does not result in an in vivo response directed at the subdominant epitope

The Journal of immunology (1950), 2004-06, Vol.172 (11), p.6658-6665

2004

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CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

Nature (London), 1992-04, Vol.356 (6370), p.607-609

1992

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Novel fluorochrome development enables 34-color high-content flow cytometry

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.159-159.1

2020

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Enhanced immunogenicity of a functional enzyme by T cell epitope modification

BMC immunology, 2002, Vol.3 (1), p.2-2

2002

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An In Vitro Human Cell–Based Assay to Rank the Relative Immunogenicity of Proteins

Toxicological sciences, 2004-02, Vol.77 (2), p.280-289

2004

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Human population-based identification of CD4 + T-cell peptide epitope determinants

Journal of immunological methods, 2003-10, Vol.281 (1), p.95-108

2003

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Blockade of CD25 reduces regulatory T cell expansion and some manifestations of IL-2 mediated toxicity but does not improve anti-tumor efficacy in animal models of IL-2 immunotherapy

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.57-57.3

2018

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CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help

The Journal of experimental medicine, 1993-06, Vol.177 (6), p.1791-1796

1993

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Elimination of an Immunodominant CD4 super(+) T Cell Epitope in Human IFN- beta Does Not Result in an In Vivo Response Directed at the Subdominant Epitope

The Journal of immunology (1950), 2004-06, Vol.172 (11), p.6658-6665

2004

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A {szligbeta}-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy

Molecular cancer therapeutics, 2005-11, Vol.4 (11), p.1791-1800

2005

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Two distinct immunoglobulin heavy chain isotypes in a primitive, cartilaginous fish, Raja erinacea

Nucleic acids research, 1990-11, Vol.18 (21), p.6369-6376

1990

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Class Switching in Human Immunoglobulin Transgenic Mice

Annals of the New York Academy of Sciences, 1995-09, Vol.764 (1), p.536-546

1995

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Immunoglobulin heavy chain gene organization and complexity in the skate, Raja erinacea

Nucleic acids research, 1990-02, Vol.18 (4), p.1015-1020

1990

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Elimination of an Immunodominant CD4+ T Cell Epitope in Human IFN-{beta} Does Not Result in an In Vivo Response Directed at the Subdominant Epitope

The Journal of immunology (1950), 2004-06, Vol.172 (11), p.6658

2004

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MHC restriction of T-cell proliferative responses in Xenopus

Developmental and comparative immunology, 1993-09, Vol.17 (5), p.425-437

1993

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Teratogen metabolism: Thalidomide activation is mediated by cytochrome P-450

Toxicology and applied pharmacology, 1986, Vol.82 (1), p.175-179

1986

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Immune system activation associated with a naturally occurring infection in Xenopus laevis

Developmental and comparative immunology, 1992-11, Vol.16 (6), p.453-462

1992

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Tuning hardness in calcite by incorporation of amino acids

Nature materials, 2016-08, Vol.15 (8), p.903-910

2016

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Protocol for the development of a core outcome set for neonatal sepsis (NESCOS)

PloS one, 2023-12, Vol.18 (12), p.e0295325-e0295325

2023

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The immunogenicity of humanized and fully human antibodies: Residual immunogenicity resides in the CDR regions

A β-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy

Design, creation and in vitro testing of a reduced immunogenicity humanized anti-CD25 monoclonal antibody that retains functional activity

Murinization and H Chain Isotype Matching of the Anti-GITR Antibody DTA-1 Reduces Immunogenicity-Mediated Anaphylaxis in C57BL/6 Mice

Antigen-specific human antibodies from mice comprising four distinct genetic modifications

Elimination of an immunodominant CD4+ T cell epitope in human IFN-beta does not result in an in vivo response directed at the subdominant epitope

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

Novel fluorochrome development enables 34-color high-content flow cytometry

Enhanced immunogenicity of a functional enzyme by T cell epitope modification

An In Vitro Human Cell–Based Assay to Rank the Relative Immunogenicity of Proteins

Human population-based identification of CD4 + T-cell peptide epitope determinants

Blockade of CD25 reduces regulatory T cell expansion and some manifestations of IL-2 mediated toxicity but does not improve anti-tumor efficacy in animal models of IL-2 immunotherapy

CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help

Elimination of an Immunodominant CD4 super(+) T Cell Epitope in Human IFN- beta Does Not Result in an In Vivo Response Directed at the Subdominant Epitope

A {szligbeta}-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy

Two distinct immunoglobulin heavy chain isotypes in a primitive, cartilaginous fish, Raja erinacea

Class Switching in Human Immunoglobulin Transgenic Mice

Immunoglobulin heavy chain gene organization and complexity in the skate, Raja erinacea

Elimination of an Immunodominant CD4+ T Cell Epitope in Human IFN-{beta} Does Not Result in an In Vivo Response Directed at the Subdominant Epitope

MHC restriction of T-cell proliferative responses in Xenopus

Teratogen metabolism: Thalidomide activation is mediated by cytochrome P-450

Immune system activation associated with a naturally occurring infection in Xenopus laevis

GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans

Tuning hardness in calcite by incorporation of amino acids

Protocol for the development of a core outcome set for neonatal sepsis (NESCOS)

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