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The immunogenicity of humanized and fully human antibodies: Residual immunogenicity resides in the CDR regions

mAbs, 2010-05, Vol.2 (3), p.256-265

2010

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Perspectives on psychedelic treatment and research in eating disorders: a web-based questionnaire study of people with eating disorders

Journal of integrative neuroscience, 2021-09, Vol.20 (3), p.551-560

2021

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Design, creation and in vitro testing of a reduced immunogenicity humanized anti-CD25 monoclonal antibody that retains functional activity

Protein engineering, design and selection, 2019-12, Vol.32 (12), p.543-554

2019

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1034 Identification of a potentially novel regulatory axis involving KIR+CD8+ HLA-E/VL9 tetramer+ T cells and HLA-Ehi cTFH

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1141-A1141

2023

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Murinization and H Chain Isotype Matching of the Anti-GITR Antibody DTA-1 Reduces Immunogenicity-Mediated Anaphylaxis in C57BL/6 Mice

The Journal of immunology (1950), 2017-06, Vol.198 (11), p.4502-4512

2017

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1143 cDC1 engagement induces Th1 differentiation and tumor regression in vivo

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1257-A1257

2023

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Identifying predictors of adverse outcomes after termination of seclusion in psychiatric intensive care units

BJPsych open, 2024-05, Vol.10 (3), p.e120-e120, Article e120

2024

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A β-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy

Molecular cancer therapeutics, 2005-11, Vol.4 (11), p.1791-1800

2005

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Elimination of an immunodominant CD4+ T cell epitope in human IFN-beta does not result in an in vivo response directed at the subdominant epitope

The Journal of immunology (1950), 2004-06, Vol.172 (11), p.6658-6665

2004

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The challenges and molecular approaches surrounding interleukin-2-based therapeutics in cancer

Cytokine: X, 2019-03, Vol.1 (1), p.100001, Article 100001

2019

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CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

Nature (London), 1992-04, Vol.356 (6370), p.607-609

1992

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A Quality Improvement Project Reviewing the Quality of Information Included in Discharge Summaries Sent to General Practitioners (GPs) From a Home Treatment Team (HTT) in an Inner London Borough

BJPsych open, 2023-07, Vol.9 (S1), p.S94-S94

2023

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TP53 STATUS RISK STRATIFIES PATIENTS WITH CLINICALLY DEFINED HIGH-RISK DISEASE PAEDIATRIC B-CELL NON-HODGKIN LYMPHOMA

Leukemia research, 2022-10, Vol.121, p.S51-S52

2022

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Antigen-specific human antibodies from mice comprising four distinct genetic modifications

Nature (London), 1994-04, Vol.368 (6474), p.856-859

1994

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Novel fluorochrome development enables 34-color high-content flow cytometry

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.159-159.1

2020

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Novel PE and APC tandems: Additional near‐infrared fluorochromes for use in spectral flow cytometry

Cytometry. Part A, 2022-10, Vol.101 (10), p.835-845

2022

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Abstract 1615: Evaluation of efficacy metrics for in vivo experiments with immuno-oncology therapeutic agents

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.1615-1615

2020

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Genomic abnormalities of TP53 define distinct risk groups of paediatric B-cell non-Hodgkin lymphoma

Leukemia, 2022-03, Vol.36 (3), p.781-789

2022

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Beyond Binding Kinetics: Stoichiometry via SPR can identify novel binding modes, assess ligand quality and inform functional design in biopharmaceutical discovery

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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An In Vitro Human Cell–Based Assay to Rank the Relative Immunogenicity of Proteins

Toxicological sciences, 2004-02, Vol.77 (2), p.280-289

2004

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Abstract 5761: Identification of Fc mutations that optimize agonistic activity of human anti-CD40 monoclonal antibodies by enhancing appropriate Fcg receptor interactions

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5761-5761

2018

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Blockade of CD25 reduces regulatory T cell expansion and some manifestations of IL-2 mediated toxicity but does not improve anti-tumor efficacy in animal models of IL-2 immunotherapy

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.57-57.3

2018

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080 - TP53 STATUS RISK STRATIFIES PATIENTS WITH CLINICALLY DEFINED HIGH-RISK DISEASE PAEDIATRIC B-CELL NON-HODGKIN LYMPHOMA

Leukemia research, 2022-10, Vol.121, p.S51-S52

2022

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Human population-based identification of CD4 + T-cell peptide epitope determinants

Journal of immunological methods, 2003-10, Vol.281 (1), p.95-108

2003

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The immunogenicity of humanized and fully human antibodies: Residual immunogenicity resides in the CDR regions

Perspectives on psychedelic treatment and research in eating disorders: a web-based questionnaire study of people with eating disorders

Design, creation and in vitro testing of a reduced immunogenicity humanized anti-CD25 monoclonal antibody that retains functional activity

1034 Identification of a potentially novel regulatory axis involving KIR+CD8+ HLA-E/VL9 tetramer+ T cells and HLA-Ehi cTFH

Murinization and H Chain Isotype Matching of the Anti-GITR Antibody DTA-1 Reduces Immunogenicity-Mediated Anaphylaxis in C57BL/6 Mice

1143 cDC1 engagement induces Th1 differentiation and tumor regression in vivo

Identifying predictors of adverse outcomes after termination of seclusion in psychiatric intensive care units

A β-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy

Elimination of an immunodominant CD4+ T cell epitope in human IFN-beta does not result in an in vivo response directed at the subdominant epitope

The challenges and molecular approaches surrounding interleukin-2-based therapeutics in cancer

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

A Quality Improvement Project Reviewing the Quality of Information Included in Discharge Summaries Sent to General Practitioners (GPs) From a Home Treatment Team (HTT) in an Inner London Borough

TP53 STATUS RISK STRATIFIES PATIENTS WITH CLINICALLY DEFINED HIGH-RISK DISEASE PAEDIATRIC B-CELL NON-HODGKIN LYMPHOMA

Antigen-specific human antibodies from mice comprising four distinct genetic modifications

Novel fluorochrome development enables 34-color high-content flow cytometry

Novel PE and APC tandems: Additional near‐infrared fluorochromes for use in spectral flow cytometry

Abstract 1615: Evaluation of efficacy metrics for in vivo experiments with immuno-oncology therapeutic agents

Genomic abnormalities of TP53 define distinct risk groups of paediatric B-cell non-Hodgkin lymphoma

Beyond Binding Kinetics: Stoichiometry via SPR can identify novel binding modes, assess ligand quality and inform functional design in biopharmaceutical discovery

An In Vitro Human Cell–Based Assay to Rank the Relative Immunogenicity of Proteins

Abstract 5761: Identification of Fc mutations that optimize agonistic activity of human anti-CD40 monoclonal antibodies by enhancing appropriate Fcg receptor interactions

Blockade of CD25 reduces regulatory T cell expansion and some manifestations of IL-2 mediated toxicity but does not improve anti-tumor efficacy in animal models of IL-2 immunotherapy

080 - TP53 STATUS RISK STRATIFIES PATIENTS WITH CLINICALLY DEFINED HIGH-RISK DISEASE PAEDIATRIC B-CELL NON-HODGKIN LYMPHOMA

An anti-PD-1-GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy

Human population-based identification of CD4 + T-cell peptide epitope determinants

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