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Identification of essential genes in cultured mammalian cells using small interfering RNAs

Journal of cell science, 2001-12, Vol.114 (Pt 24), p.4557-4565

2001

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The mitotic-spindle-associated protein astrin is essential for progression through mitosis

Journal of cell science, 2002-11, Vol.115 (Pt 21), p.4053-4059

2002

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Essential Roles for Four Cytoplasmic Intermediate Filament Proteins in Caenorhabditis elegans Development

Proceedings of the National Academy of Sciences - PNAS, 2001-07, Vol.98 (14), p.7863-7868

2001

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Targeting Lysophosphatidic Acid Receptor 1 (LPAR1) with siRNA-Lipid Nanoparticles (siRNA-LNP) Is a Potential Therapeutic Approach for CKD -Associated Kidney Fibrosis: SA-PO443

Journal of the American Society of Nephrology, 2023-11, Vol.34 (11S), p.846-846

2023

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Nature (London), 2001-05, Vol.411 (6836), p.494-498

2001

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Analysis of gene function in somatic mammalian cells using small interfering RNAs

Methods (San Diego, Calif.), 2002-02, Vol.26 (2), p.199-213

2002

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RNAi-mediated gene silencing in non-human primates

Nature, 2006-05, Vol.441 (7089), p.111-114

2006

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Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV)

Antiviral research, 2008-03, Vol.77 (3), p.225-231

2008

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Abstract 4060: Discovery and preclinical development of KRAS-targeting siRNA therapeutic modality for the treatment of pancreatic cancer

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.4060-4060

2020

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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

Nature, 2004-11, Vol.432 (7014), p.173-178

2004

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Abstract 5918: A novel glutathione S-transferase P (GSTP) siRNA (NDT-05-1040) for the treatment of KRAS-driven non-small cell lung cancer

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5918-5918

2018

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Effect of Clathrin Heavy Chain- and α-Adaptin-specific Small Inhibitory RNAs on Endocytic Accessory Proteins and Receptor Trafficking in HeLa Cells

The Journal of biological chemistry, 2003-11, Vol.278 (46), p.45160-45170

2003

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Abstract 5917: A novel lipid nanoparticle (NBF-006) encapsulating glutathione S-transferase P (GSTP) siRNA for the treatment of KRAS-driven non-small cell lung cancer

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5917-5917

2018

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Nucleoplasmic LAP2α-Lamin A Complexes Are Required to Maintain a Proliferative State in Human Fibroblasts

The Journal of cell biology, 2007-01, Vol.176 (2), p.163-172

2007

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Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing

Antisense & nucleic acid drug development, 2003-04, Vol.13 (2), p.83-105

2003

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Self assembly of NuMA: multiarm oligomers as structural units of a nuclear lattice

The EMBO journal, 1999-03, Vol.18 (6), p.1689-1700

1999

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Abstract 4513: IND-enabling studies for CEQ508 targeting β-catenin of GI polyps: First oral RNAi drug

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.4513-4513

2010

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565 Ind-Enabling Studies for CEQ508 Targeting β-Catenin of GI Polyps: First Oral RNAI Drug

Gastroenterology (New York, N.Y. 1943), 2010, Vol.138 (5), p.S-79-S-79

2010

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Effects of expressing lamin A mutant protein causing Emery-Dreifuss muscular dystrophy and familial partial lipodystrophy in Hela cells

Experimental cell research, 2003-05, Vol.286 (1), p.75-86

2003

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Nucleoplasmic LAP2[alpha]-lamin A complexes are required to maintain a proliferative state in human fibroblasts

The Journal of cell biology, 2007-01, Vol.176 (2), p.163

2007

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Induction of a Regular Nuclear Lattice by Overexpression of NuMA

Experimental cell research, 1998-09, Vol.243 (2), p.434-452

1998

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Nucleoplasmic LAP2alpha-lamin A complexes are required to maintain a proliferative state in human fibroblasts

The Journal of cell biology, 2007-01, Vol.176 (2), p.163

2007

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Abstract 583: RNAi Therapeutics For The Lowering Of Cholesterol

Circulation (New York, N.Y.), 2007-10, Vol.116 (suppl_16)

2007

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Epitope mapping and direct visualization of the parallel, in‐register arrangement of the double‐stranded coiled‐coil in the NuMA protein

The EMBO journal, 1995-06, Vol.14 (11), p.2447-2460

1995

Volltextzugriff (PDF)

Effect of Clathrin Heavy Chain- and Î±-Adaptin-specific Small Inhibitory RNAs on Endocytic Accessory Proteins and Receptor Trafficking in HeLa Cells

The Journal of biological chemistry, 2003-11, Vol.278 (46), p.45160

2003

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Identification of essential genes in cultured mammalian cells using small interfering RNAs

The mitotic-spindle-associated protein astrin is essential for progression through mitosis

Essential Roles for Four Cytoplasmic Intermediate Filament Proteins in Caenorhabditis elegans Development

Targeting Lysophosphatidic Acid Receptor 1 (LPAR1) with siRNA-Lipid Nanoparticles (siRNA-LNP) Is a Potential Therapeutic Approach for CKD -Associated Kidney Fibrosis: SA-PO443

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Analysis of gene function in somatic mammalian cells using small interfering RNAs

RNAi-mediated gene silencing in non-human primates

Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV)

Abstract 4060: Discovery and preclinical development of KRAS-targeting siRNA therapeutic modality for the treatment of pancreatic cancer

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

Abstract 5918: A novel glutathione S-transferase P (GSTP) siRNA (NDT-05-1040) for the treatment of KRAS-driven non-small cell lung cancer

Effect of Clathrin Heavy Chain- and α-Adaptin-specific Small Inhibitory RNAs on Endocytic Accessory Proteins and Receptor Trafficking in HeLa Cells

Abstract 5917: A novel lipid nanoparticle (NBF-006) encapsulating glutathione S-transferase P (GSTP) siRNA for the treatment of KRAS-driven non-small cell lung cancer

Nucleoplasmic LAP2α-Lamin A Complexes Are Required to Maintain a Proliferative State in Human Fibroblasts

Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing

Self assembly of NuMA: multiarm oligomers as structural units of a nuclear lattice

Abstract 4513: IND-enabling studies for CEQ508 targeting β-catenin of GI polyps: First oral RNAi drug

565 Ind-Enabling Studies for CEQ508 Targeting β-Catenin of GI Polyps: First Oral RNAI Drug

Effects of expressing lamin A mutant protein causing Emery-Dreifuss muscular dystrophy and familial partial lipodystrophy in Hela cells

Nucleoplasmic LAP2[alpha]-lamin A complexes are required to maintain a proliferative state in human fibroblasts

Induction of a Regular Nuclear Lattice by Overexpression of NuMA

Nucleoplasmic LAP2alpha-lamin A complexes are required to maintain a proliferative state in human fibroblasts

Abstract 583: RNAi Therapeutics For The Lowering Of Cholesterol

Epitope mapping and direct visualization of the parallel, in‐register arrangement of the double‐stranded coiled‐coil in the NuMA protein

Effect of Clathrin Heavy Chain- and Î±-Adaptin-specific Small Inhibitory RNAs on Endocytic Accessory Proteins and Receptor Trafficking in HeLa Cells

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