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Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity

Nature communications, 2018-02, Vol.9 (1), p.723-10, Article 723

2018

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Limited Transferrin Receptor Clustering Allows Rapid Diffusion of Canine Parvovirus into Clathrin Endocytic Structures

Journal of Virology, 2012-05, Vol.86 (9), p.5330-5340

2012

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Evolutionary reconstructions of the transferrin receptor of Caniforms supports canine parvovirus being a re-emerged and not a novel pathogen in dogs

PLoS pathogens, 2012-05, Vol.8 (5), p.e1002666-e1002666

2012

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Role of Multiple Hosts in the Cross-Species Transmission and Emergence of a Pandemic Parvovirus

Journal of Virology, 2012-01, Vol.86 (2), p.865-872

2012

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Examining the cross-reactivity and neutralization mechanisms of a panel of mAbs against adeno-associated virus serotypes 1 and 5

Journal of general virology, 2012-02, Vol.93 (Pt 2), p.347-355

2012

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Early Steps in Cell Infection by Parvoviruses: Host-Specific Differences in Cell Receptor Binding but Similar Endosomal Trafficking

Journal of Virology, 2009-10, Vol.83 (20), p.10504-10514

2009

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The Nonclinical Safety Profile of GalNAc-conjugated RNAi Therapeutics in Subacute Studies

Toxicologic Pathology, 2018-10, Vol.46 (7), p.735-745

2018

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Scientific and Regulatory Policy Committee Points to Consider: Biological Sample Retention From Nonclinical Toxicity Studies

Toxicologic pathology, 2022-02, Vol.50 (2), p.252-265

2022

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Effects of canine parvovirus strain variations on diagnostic test results and clinical management of enteritis in dogs

Journal of the American Veterinary Medical Association, 2012-07, Vol.241 (1), p.66-72

2012

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The parvovirus capsid odyssey: from the cell surface to the nucleus

Trends in microbiology (Regular ed.), 2008-05, Vol.16 (5), p.208-214

2008

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Spontaneous Cervicovaginal Lesions and Immune Cell Infiltrates in Nonhuman Primates

Toxicologic pathology, 2013-10, Vol.41 (7), p.1016-1027

2013

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Feline aminopeptidase N is not a functional receptor for avian infectious bronchitis virus

Virology journal, 2007-02, Vol.4 (1), p.20-20, Article 20

2007

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Abstract CT249: First-in-human study of TAK-500, a novel STING agonist immune stimulating antibody conjugate (ISAC), alone and in combination with pembrolizumab in patients with select advanced solid tumors

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.CT249-CT249

2022

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Abstract 1841: TAK-500 is a clinical stage immune-cell directed antibody drug conjugate (iADC) inducing STING activation in CCR2-expressing intratumor myeloid cells and favorable immunomodulation

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.1841-1841

2023

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Evolutionary reconstructions of the transferrin receptor of caniforms supports canine parvovirus being a reemerged and not a novel pathogen in dogs

PLoS pathogens, 2012-05, Vol.8 (5)

2012

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Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

The Journal of clinical investigation, 2017-11, Vol.127 (11), p.4059-4074

2017

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Phase 1a/1b study design of the novel STING agonist, immune-stimulating antibody-conjugate (ISAC) TAK-500, with or without pembrolizumab in patients with advanced solid tumors

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.TPS2690-TPS2690

2022

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Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

The Journal of clinical investigation, 2018-03, Vol.128 (3), p.1199-1199

2018

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Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

The Journal of clinical investigation, 2017-11, Vol.127 (11), p.4059

2017

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Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity

Limited Transferrin Receptor Clustering Allows Rapid Diffusion of Canine Parvovirus into Clathrin Endocytic Structures

Evolutionary reconstructions of the transferrin receptor of Caniforms supports canine parvovirus being a re-emerged and not a novel pathogen in dogs

Role of Multiple Hosts in the Cross-Species Transmission and Emergence of a Pandemic Parvovirus

Examining the cross-reactivity and neutralization mechanisms of a panel of mAbs against adeno-associated virus serotypes 1 and 5

Early Steps in Cell Infection by Parvoviruses: Host-Specific Differences in Cell Receptor Binding but Similar Endosomal Trafficking

The Nonclinical Safety Profile of GalNAc-conjugated RNAi Therapeutics in Subacute Studies

Scientific and Regulatory Policy Committee Points to Consider: Biological Sample Retention From Nonclinical Toxicity Studies

Effects of canine parvovirus strain variations on diagnostic test results and clinical management of enteritis in dogs

The parvovirus capsid odyssey: from the cell surface to the nucleus

Spontaneous Cervicovaginal Lesions and Immune Cell Infiltrates in Nonhuman Primates

Feline aminopeptidase N is not a functional receptor for avian infectious bronchitis virus

Abstract CT249: First-in-human study of TAK-500, a novel STING agonist immune stimulating antibody conjugate (ISAC), alone and in combination with pembrolizumab in patients with select advanced solid tumors

Abstract 1841: TAK-500 is a clinical stage immune-cell directed antibody drug conjugate (iADC) inducing STING activation in CCR2-expressing intratumor myeloid cells and favorable immunomodulation

Evolutionary reconstructions of the transferrin receptor of caniforms supports canine parvovirus being a reemerged and not a novel pathogen in dogs

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

Phase 1a/1b study design of the novel STING agonist, immune-stimulating antibody-conjugate (ISAC) TAK-500, with or without pembrolizumab in patients with advanced solid tumors

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

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