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Tuning a Protein‐Labeling Reaction to Achieve Highly Site Selective Lysine Conjugation

Chembiochem : a European journal of chemical biology, 2018-04, Vol.19 (8), p.799-804

2018

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In vivo Incorporation of Unnatural Amino Acids to Probe Structure, Dynamics, and Ligand Binding in a Large Protein by Nuclear Magnetic Resonance Spectroscopy

Journal of the American Chemical Society, 2008-07, Vol.130 (29), p.9268-9281

2008

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A Dual Inhibitor of DYRK1A and GSK3β for β‐Cell Proliferation: Aminopyrazine Derivative GNF4877

ChemMedChem, 2020-08, Vol.15 (16), p.1562-1570

2020

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Site-specific protein modifications through pyrroline-carboxy-lysine residues

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (26), p.10437-10442

2011

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Design and synthesis of benzoazepin-2-one analogs as allosteric binders targeting the PIF pocket of PDK1

Bioorganic & medicinal chemistry letters, 2010-07, Vol.20 (13), p.3897-3902

2010

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D-Ornithine coopts pyrrolysine biosynthesis to make and insert pyrroline-carboxy-lysine

Nature chemical biology, 2011-04, Vol.7 (8), p.528-530

2011

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Discovery of 5‑(3,4-Difluorophenyl)-3-(pyrazol-4-yl)-7-azaindole (GNF3809) for β‑Cell Survival in Type 1 Diabetes

ACS omega, 2019-02, Vol.4 (2), p.3571-3581

2019

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Reversed Stereoselectivity in Iodohydroxylation of Allenyl Sulfides. An Efficient Synthesis of (Z)-3-Organosulfur-2-iodo-2-propenols

Organic letters, 2003-04, Vol.5 (8), p.1217-1219

2003

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Studies on the Regio- and Stereoselectivity of Halohydroxylation of 1,2-Allenyl Sulfides or Selenides

Journal of organic chemistry, 2004-08, Vol.69 (17), p.5720-5724

2004

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Simultaneous Purification and Site-Specific Modification of Pyrroline-Carboxy-Lysine Proteins

Chembiochem : a European journal of chemical biology, 2012-02, Vol.13 (3), p.364-366

2012

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Inhibition of DYRK1A and GSK3B induces human β-cell proliferation

Nature communications, 2015-10, Vol.6 (1), p.8372, Article 8372

2015

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Pancreas-Specific Delivery of [beta]-Cell Proliferating Small Molecules

ChemMedChem, 2016-06, Vol.11 (11), p.1129

2016

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Site-specific labeling of proteins with NMR-active unnatural amino acids

Journal of biomolecular NMR, 2010, Vol.46 (1), p.89-100

2010

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Pancreas-Specific Delivery of β-Cell Proliferating Small Molecules

ChemMedChem, 2016-06, Vol.11 (11), p.1129-1132

2016

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Highly regio- and stereoselective four-component iodoamination of Se-substituted allenes. An efficient synthesis of N-(3-organoseleno-2-iodo-2(Z)-propenyl) acetamides

Chemical communications (Cambridge, England), 2003-05 (9), p.1082-1083

2003

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Highly regio- and stereoselective four-component iodoamination of Se-substituted allenes. an efficient synthesis of N-(3-organoseleno-2-iodo-2(Z)-propenyl) acetamidesElectronic supplementary information (ESI) available: experimental section. See http://www.rsc.org/suppdata/cc/b3/b300879g

Chemical communications (Cambridge, England), 2003-04 (9), p.1082-1083

2003

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Inhibition of DYRK1A and GSK3B induces human [beta]-cell proliferation

Nature communications, 2015-10, Vol.6, p.8372

2015

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Highly Regio- and Stereoselective Four-Component Iodoamination of Se-Substituted Allenes. An Efficient Synthesis of N-(3-Organoseleno-2-iodo-2(Z)-propenyl) Acetamides

ChemInform, 2003-08, Vol.34 (33), p.no-no

2003

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Reversed Stereoselectivity in Iodohydroxylation of Allenyl Sulfides. An Efficient Synthesis of (Z)-3-Organosulfur-2-iodo-2-propenols

ChemInform, 2003-08, Vol.34 (32), p.no-no

2003

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Studies on the Regio- and Stereoselectivity of Halohydroxylation of 1,2-Allenyl Sulfides or Selenides

ChemInform, 2004-12, Vol.35 (50), p.no-no

2004

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Potential targets for the development of new antifungal drugs

Journal of antibiotics, 2018-12, Vol.71 (12), p.978-991

2018

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Tailoring solid-state single-photon sources with stimulated emissions

Nature nanotechnology, 2022-05, Vol.17 (5), p.470-476

2022

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IL-1β-activated mTORC2 promotes accumulation of IFN-γ + γδ T cells by upregulating CXCR3 to restrict hepatic fibrosis

Cell death & disease, 2022-04, Vol.13 (4), p.289-289, Article 289

2022

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Effects of Astragaloside IV on Action Potentials and Ionic Currents in Guinea-Pig Ventricular Myocytes

Biological and Pharmaceutical Bulletin, 2013/04/01, Vol.36(4), pp.515-521

2013

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Tuning a Protein‐Labeling Reaction to Achieve Highly Site Selective Lysine Conjugation

In vivo Incorporation of Unnatural Amino Acids to Probe Structure, Dynamics, and Ligand Binding in a Large Protein by Nuclear Magnetic Resonance Spectroscopy

A Dual Inhibitor of DYRK1A and GSK3β for β‐Cell Proliferation: Aminopyrazine Derivative GNF4877

Site-specific protein modifications through pyrroline-carboxy-lysine residues

Design and synthesis of benzoazepin-2-one analogs as allosteric binders targeting the PIF pocket of PDK1

D-Ornithine coopts pyrrolysine biosynthesis to make and insert pyrroline-carboxy-lysine

Discovery of 5‑(3,4-Difluorophenyl)-3-(pyrazol-4-yl)-7-azaindole (GNF3809) for β‑Cell Survival in Type 1 Diabetes

Reversed Stereoselectivity in Iodohydroxylation of Allenyl Sulfides. An Efficient Synthesis of (Z)-3-Organosulfur-2-iodo-2-propenols

Studies on the Regio- and Stereoselectivity of Halohydroxylation of 1,2-Allenyl Sulfides or Selenides

Simultaneous Purification and Site-Specific Modification of Pyrroline-Carboxy-Lysine Proteins

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation

Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6‑Azaindole Derivative GNF2133

Pancreas-Specific Delivery of [beta]-Cell Proliferating Small Molecules

Site-specific labeling of proteins with NMR-active unnatural amino acids

Pancreas-Specific Delivery of β-Cell Proliferating Small Molecules

Highly regio- and stereoselective four-component iodoamination of Se-substituted allenes. An efficient synthesis of N-(3-organoseleno-2-iodo-2(Z)-propenyl) acetamides

Highly regio- and stereoselective four-component iodoamination of Se-substituted allenes. an efficient synthesis of N-(3-organoseleno-2-iodo-2(Z)-propenyl) acetamidesElectronic supplementary information (ESI) available: experimental section. See http://www.rsc.org/suppdata/cc/b3/b300879g

Inhibition of DYRK1A and GSK3B induces human [beta]-cell proliferation

Highly Regio- and Stereoselective Four-Component Iodoamination of Se-Substituted Allenes. An Efficient Synthesis of N-(3-Organoseleno-2-iodo-2(Z)-propenyl) Acetamides

Reversed Stereoselectivity in Iodohydroxylation of Allenyl Sulfides. An Efficient Synthesis of (Z)-3-Organosulfur-2-iodo-2-propenols

Studies on the Regio- and Stereoselectivity of Halohydroxylation of 1,2-Allenyl Sulfides or Selenides

Potential targets for the development of new antifungal drugs

Tailoring solid-state single-photon sources with stimulated emissions

IL-1β-activated mTORC2 promotes accumulation of IFN-γ + γδ T cells by upregulating CXCR3 to restrict hepatic fibrosis

Effects of Astragaloside IV on Action Potentials and Ionic Currents in Guinea-Pig Ventricular Myocytes

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