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Perfluoroaryl Bicyclic Cell‐Penetrating Peptides for Delivery of Antisense Oligonucleotides

Angewandte Chemie International Edition, 2018-04, Vol.57 (17), p.4756-4759

International ed. in English, 2018

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Fully automated fast-flow synthesis of antisense phosphorodiamidate morpholino oligomers

Nature communications, 2021-07, Vol.12 (1), p.4396-8, Article 4396

2021

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Functional muscle recovery following dystrophin and myostatin exon splice modulation in aged mdx mice

Human molecular genetics, 2019-09, Vol.28 (18), p.3091-3100

2019

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A cell-penetrating peptide enhances delivery and efficacy of phosphorodiamidate morpholino oligomers in mdx mice

Molecular therapy. Nucleic acids, 2022-12, Vol.30, p.17-27

2022

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Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery

ACS central science, 2018-04, Vol.4 (4), p.512-520

2018

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Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90

Bioorganic & medicinal chemistry, 2008-06, Vol.18 (12), p.3517-3521

2008

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Synthesis, Crystal Structure, and Activity of Pyrazole-Based Inhibitors of p38 Kinase

Journal of medicinal chemistry, 2007-11, Vol.50 (23), p.5712-5719

2007

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Chimeras of Cell-Penetrating Peptides Demonstrate Synergistic Improvement in Antisense Efficacy

Biochemistry (Easton), 2019-09, Vol.58 (38), p.3980-3989

2019

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Perfluoroaryl Bicyclic Cell‐Penetrating Peptides for Delivery of Antisense Oligonucleotides

Angewandte Chemie, 2018-04, Vol.130 (17), p.4846-4849

2018

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Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90

Bioorganic & medicinal chemistry letters, 2012-04, Vol.22 (7), p.2550-2554

2012

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Novel carbazole and acyl-indole antimitotics

Bioorganic & medicinal chemistry letters, 2009-06, Vol.19 (11), p.3078-3080

2009

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Synthesis of new dipeptide analogs containing novel ketovinyl and hydroxyethylidene isosteres via Grignard addition to chiral .alpha.-amino aldehydes

Journal of organic chemistry, 1985-12, Vol.50 (25), p.5399-5401

1985

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Development of PPMO for the Treatment of Duchenne Muscular Dystrophy (P5.430)

Neurology, 2018-04, Vol.90 (15_supplement)

2018

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Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents

Journal of medicinal chemistry, 2009-07, Vol.52 (14), p.4288-4305

2009

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A peptidomimetic that specifically inhibits human leukocyte antigen DRB10401-restricted T cell proliferation

The Journal of pharmacology and experimental therapeutics, 1997-05, Vol.281 (2), p.663

1997

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Effects of SC-56525, a Potent, Orally Active Renin Inhibitor, in Salt-Depleted and Renal Hypertensive Dogs

Hypertension (Dallas, Tex. 1979), 1995-07, Vol.26 (1), p.95-100

1995

Volltextzugriff (PDF)

Stereoselective addition of lithioethyl acetate to Boc- l-prolinal. A convenient chiral synthetic building block for the pyrrolizidine alkaloid ring system

Tetrahedron letters, 1986, Vol.27 (31), p.3577-3580

1986

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Discovery of benzamide tetrahydro-4 H-carbazol-4-ones as novel small molecule inhibitors of Hsp90

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (12), p.3517-3521

2008

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Inhibitors of p38 kinase

Expert opinion on therapeutic patents, 1997-07, Vol.7 (7), p.729-733

Hanson, Gunnar J

1997

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DR (MHC class II) ligands: an approach to rheumatoid arthritis therapeutics

Current pharmaceutical design, 1998-10, Vol.4 (5), p.397-402

Hanson, G J

1998

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Design of MHC class II (DR4) ligands using conformationally restricted imino acids at p3 and p5

Bioorganic & medicinal chemistry letters, 1996-08, Vol.6 (16), p.1931-1936

1996

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Stereoselective Δ 4-pipecolic acid synthesis via alkylation of a vinyl N-Boc-iminium ion derived from Baikiain

Tetrahedron letters, 1989, Vol.30 (42), p.5751-5754

1989

Volltextzugriff (PDF)

Stereoselective Δ4-pipecolic acid synthesis via alkylation of a vinyl N-Boc-iminium ion derived from Baikiain

Tetrahedron letters, 1989-01, Vol.30 (42), p.5751-5754

1989

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Renin inhibitor SC-51106 complexed with human renin: discovery of a new binding site adjacent to P3

Bioorganic & medicinal chemistry, 1994-09, Vol.2 (9), p.909-918

1994

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Perfluoroaryl Bicyclic Cell‐Penetrating Peptides for Delivery of Antisense Oligonucleotides

Fully automated fast-flow synthesis of antisense phosphorodiamidate morpholino oligomers

Functional muscle recovery following dystrophin and myostatin exon splice modulation in aged mdx mice

A cell-penetrating peptide enhances delivery and efficacy of phosphorodiamidate morpholino oligomers in mdx mice

Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery

Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90

Synthesis, Crystal Structure, and Activity of Pyrazole-Based Inhibitors of p38 Kinase

Chimeras of Cell-Penetrating Peptides Demonstrate Synergistic Improvement in Antisense Efficacy

Perfluoroaryl Bicyclic Cell‐Penetrating Peptides for Delivery of Antisense Oligonucleotides

Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90

Novel carbazole and acyl-indole antimitotics

Synthesis of new dipeptide analogs containing novel ketovinyl and hydroxyethylidene isosteres via Grignard addition to chiral .alpha.-amino aldehydes

Development of PPMO for the Treatment of Duchenne Muscular Dystrophy (P5.430)

Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents

A peptidomimetic that specifically inhibits human leukocyte antigen DRB10401-restricted T cell proliferation

Effects of SC-56525, a Potent, Orally Active Renin Inhibitor, in Salt-Depleted and Renal Hypertensive Dogs

Stereoselective addition of lithioethyl acetate to Boc- l-prolinal. A convenient chiral synthetic building block for the pyrrolizidine alkaloid ring system

Discovery of benzamide tetrahydro-4 H-carbazol-4-ones as novel small molecule inhibitors of Hsp90

Inhibitors of p38 kinase

DR (MHC class II) ligands: an approach to rheumatoid arthritis therapeutics

Design of MHC class II (DR4) ligands using conformationally restricted imino acids at p3 and p5

Application of Chemoproteomics to Drug Discovery: Identification of a Clinical Candidate Targeting Hsp90

Stereoselective Δ 4-pipecolic acid synthesis via alkylation of a vinyl N-Boc-iminium ion derived from Baikiain

Stereoselective Δ4-pipecolic acid synthesis via alkylation of a vinyl N-Boc-iminium ion derived from Baikiain

Renin inhibitor SC-51106 complexed with human renin: discovery of a new binding site adjacent to P3

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