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A happy cell stays home: When metabolic stress creates epigenetic advantages in the tumor microenvironment

Frontiers in oncology, 2022-08, Vol.12, p.962928

2022

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MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1

Nature communications, 2019-02, Vol.10 (1), p.809-809, Article 809

2019

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Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth

Nature communications, 2020-07, Vol.11 (1), p.3326-15, Article 3326

2020

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p53 Promotes Cancer Cell Adaptation to Glutamine Deprivation by Upregulating Slc7a3 to Increase Arginine Uptake

Cell reports (Cambridge), 2019-03, Vol.26 (11), p.3051-3060.e4

2019

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The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8 + T cells

Nature (London), 2018-07, Vol.559 (7713), p.264-268

2018

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EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection

Cell, 2016-02, Vol.164 (5), p.884-895

2016

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SAPS3 subunit of protein phosphatase 6 is an AMPK inhibitor and controls metabolic homeostasis upon dietary challenge in male mice

Nature communications, 2023-03, Vol.14 (1), p.1368-1368, Article 1368

2023

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A Novel Assessment of Metabolic Pathways in Peritoneal Metastases from Low-Grade Appendiceal Mucinous Neoplasms

Annals of surgical oncology, 2023-08, Vol.30 (8), p.5132-5141

2023

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Ionized calcium in human cerebrospinal fluid and its influence on intrinsic and synaptic excitability of hippocampal pyramidal neurons in the rat

Journal of neurochemistry, 2019-05, Vol.149 (4), p.452-470

2019

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α-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer

Nature cancer, 2020-03, Vol.1 (3), p.345

2020

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Alpha-Ketoglutarate Regulates Tnfrsf12a/Fn14 Expression via Histone Modification and Prevents Cancer-Induced Cachexia

Genes, 2023-09, Vol.14 (9), p.1818

2023

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Cyclin D1 inhibits hepatic lipogenesis via repression of carbohydrate response element binding protein and hepatocyte nuclear factor 4α

Cell cycle (Georgetown, Tex.), 2012-07, Vol.11 (14), p.2681-2690

2012

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Robust Generation of Person-Specific, Synchronously Active Neuronal Networks Using Purely Isogenic Human iPSC-3D Neural Aggregate Cultures

Frontiers in neuroscience, 2019-04, Vol.13, p.351-351

2019

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Neuromodulation via the Cerebrospinal Fluid: Insights from Recent in Vitro Studies

Frontiers in neural circuits, 2018-02, Vol.12, p.5-5

2018

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The B56α subunit of PP2A is necessary for mesenchymal stem cell commitment to adipocyte

EMBO reports, 2021-08, Vol.22 (8), p.e51910-n/a

2021

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Astrocytes play a critical role in transient heterosynaptic depression in the rat hippocampal CA1 region

The Journal of physiology, 2007-12, Vol.585 (3), p.843-852

2007

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The Small and Dynamic Pre-primed Pool at the Release Site; A Useful Concept to Understand Release Probability and Short-Term Synaptic Plasticity?

Frontiers in synaptic neuroscience, 2019-03, Vol.11, p.7-7

2019

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Activation of GFRAL+ neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor

Cell reports (Cambridge), 2024-04, Vol.43 (4), p.113960-113960, Article 113960

2024

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Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation

Scientific reports, 2016-07, Vol.6 (1), p.29200-29200, Article 29200

2016

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Postsynaptic Induction of BDNF-Mediated Long-Term Potentiation

Science (American Association for the Advancement of Science), 2002-03, Vol.295 (5560), p.1729-1734

2002

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Cerebrospinal fluid levels of complement proteins C3, C4 and CR1 in Alzheimer’s disease

Journal of Neural Transmission, 2012-07, Vol.119 (7), p.789-797

2012

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EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection

Cell, 2016-04, Vol.165 (2), p.497-497

2016

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Differential acute impact of therapeutically effective and overdose concentrations of lithium on human neuronal single cell and network function

Translational psychiatry, 2021-05, Vol.11 (1), p.281-281, Article 281

2021

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Genomewide microRNA down‐regulation as a negative feedback mechanism in the early phases of liver regeneration

Hepatology (Baltimore, Md.), 2011-08, Vol.54 (2), p.609-619

2011

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A happy cell stays home: When metabolic stress creates epigenetic advantages in the tumor microenvironment

MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1

Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth

p53 Promotes Cancer Cell Adaptation to Glutamine Deprivation by Upregulating Slc7a3 to Increase Arginine Uptake

The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8 + T cells

EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection

SAPS3 subunit of protein phosphatase 6 is an AMPK inhibitor and controls metabolic homeostasis upon dietary challenge in male mice

A Novel Assessment of Metabolic Pathways in Peritoneal Metastases from Low-Grade Appendiceal Mucinous Neoplasms

Ionized calcium in human cerebrospinal fluid and its influence on intrinsic and synaptic excitability of hippocampal pyramidal neurons in the rat

α-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer

Alpha-Ketoglutarate Regulates Tnfrsf12a/Fn14 Expression via Histone Modification and Prevents Cancer-Induced Cachexia

Cyclin D1 inhibits hepatic lipogenesis via repression of carbohydrate response element binding protein and hepatocyte nuclear factor 4α

Robust Generation of Person-Specific, Synchronously Active Neuronal Networks Using Purely Isogenic Human iPSC-3D Neural Aggregate Cultures

Neuromodulation via the Cerebrospinal Fluid: Insights from Recent in Vitro Studies

The B56α subunit of PP2A is necessary for mesenchymal stem cell commitment to adipocyte

Astrocytes play a critical role in transient heterosynaptic depression in the rat hippocampal CA1 region

The Small and Dynamic Pre-primed Pool at the Release Site; A Useful Concept to Understand Release Probability and Short-Term Synaptic Plasticity?

Activation of GFRAL+ neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor

Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation

Postsynaptic Induction of BDNF-Mediated Long-Term Potentiation

Cerebrospinal fluid levels of complement proteins C3, C4 and CR1 in Alzheimer’s disease

EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection

Differential acute impact of therapeutically effective and overdose concentrations of lithium on human neuronal single cell and network function

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria

Genomewide microRNA down‐regulation as a negative feedback mechanism in the early phases of liver regeneration

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