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Cardiologist-level arrhythmia detection and classification in ambulatory electrocardiograms using a deep neural network

Nature medicine, 2019-01, Vol.25 (1), p.65-69

2019

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The acid sphingomyelinase/ceramide pathway: biomedical significance and mechanisms of regulation

Current molecular medicine, 2010-07, Vol.10 (5), p.454-466

2010

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Functions of Ceramide in Coordinating Cellular Responses to Stress

Science (American Association for the Advancement of Science), 1996-12, Vol.274 (5294), p.1855-1859

Hannun, Yusuf A.

1996

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Apoptosis and the dilemma of cancer chemotherapy

Blood, 1997-03, Vol.89 (6), p.1845-1853

HANNUN, Y. A

1997

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P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment

Oncogene, 2017-11, Vol.36 (47), p.6649-6657

2017

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The sphingomyelin cycle and the second messenger function of ceramide

The Journal of biological chemistry, 1994-02, Vol.269 (5), p.3125-3128

HANNUN, Y. A

1994

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P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest

Cell death & disease, 2015-10, Vol.6 (10), p.e1947-e1947

2015

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Enzymes of Sphingolipid Metabolism: From Modular to Integrative Signaling

Biochemistry (Easton), 2001-04, Vol.40 (16), p.4893-4903

2001

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Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid

Oncogene, 2016-05, Vol.35 (21), p.2801-2812

2016

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Protein kinase C and phospholipase D: intimate interactions in intracellular signaling

Cellular and molecular life sciences : CMLS, 2005-07, Vol.62 (13), p.1448-1461

2005

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Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis

The FASEB journal, 2001-12, Vol.15 (14), p.2669-2679

2001

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Defining a role for sphingosine kinase 1 in p53-dependent tumors

Oncogene, 2012-03, Vol.31 (9), p.1166-1175

2012

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Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system

Cell death & disease, 2016-03, Vol.7 (3), p.e2124-e2124

2016

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Sphingolipids in inflammation: roles and implications

Current molecular medicine, 2004-06, Vol.4 (4), p.405-418

2004

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Sphingolipid-binding proteins

Biochimica et biophysica acta, 2006-08, Vol.1761 (8), p.927-946

2006

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Ceramide in the eukaryotic stress response

Trends in Cell Biology, 2000-02, Vol.10 (2), p.73-80

2000

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Ceramide and apoptosis

Trends in biochemical sciences (Amsterdam. Regular ed.), 1999-06, Vol.24 (6), p.224-225

1999

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Regulation of membrane trafficking and endocytosis by protein kinase C: emerging role of the pericentrion, a novel protein kinase C-dependent subset of recycling endosomes

Cellular and molecular life sciences : CMLS, 2007-02, Vol.64 (3), p.263-270

2007

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Ceramide: an intracellular signal for apoptosis

Trends in Biochemical Sciences, 1995-02, Vol.20 (2), p.73-77

1995

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Programmed Cell Death Induced by Ceramide

Science (American Association for the Advancement of Science), 1993-03, Vol.259 (5102), p.1769-1771

1993

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Ceramide activates heterotrimeric protein phosphatase 2A

The Journal of biological chemistry, 1993-07, Vol.268 (21), p.15523-15530

1993

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Identification of arachidonic acid as a mediator of sphingomyelin hydrolysis in response to tumor necrosis factor alpha

The Journal of biological chemistry, 1994-02, Vol.269 (8), p.5757-5763

1994

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Modulation of Ceramide Metabolism Enhances Viral Protein Apoptin's Cytotoxicity in Prostate Cancer

Molecular therapy, 2006-11, Vol.14 (5), p.637-646

2006

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Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor

Science (American Association for the Advancement of Science), 1994-09, Vol.265 (5178), p.1596-1599

1994

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Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C?

The Journal of biological chemistry, 1998-06, Vol.273 (23), p.14550-14559

1998

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Cardiologist-level arrhythmia detection and classification in ambulatory electrocardiograms using a deep neural network

The acid sphingomyelinase/ceramide pathway: biomedical significance and mechanisms of regulation

Functions of Ceramide in Coordinating Cellular Responses to Stress

Apoptosis and the dilemma of cancer chemotherapy

P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment

The sphingomyelin cycle and the second messenger function of ceramide

P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest

Enzymes of Sphingolipid Metabolism: From Modular to Integrative Signaling

Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid

Protein kinase C and phospholipase D: intimate interactions in intracellular signaling

Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis

Defining a role for sphingosine kinase 1 in p53-dependent tumors

Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system

Sphingolipids in inflammation: roles and implications

Sphingolipid-binding proteins

Ceramide in the eukaryotic stress response

Ceramide and apoptosis

Regulation of membrane trafficking and endocytosis by protein kinase C: emerging role of the pericentrion, a novel protein kinase C-dependent subset of recycling endosomes

Ceramide: an intracellular signal for apoptosis

Programmed Cell Death Induced by Ceramide

Ceramide activates heterotrimeric protein phosphatase 2A

Identification of arachidonic acid as a mediator of sphingomyelin hydrolysis in response to tumor necrosis factor alpha

Modulation of Ceramide Metabolism Enhances Viral Protein Apoptin's Cytotoxicity in Prostate Cancer

Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor

Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C?

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