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Antitrypanosomal compounds from the essential oil and extracts of Keetia leucantha leaves with inhibitor activity on Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase

Phytomedicine (Stuttgart), 2013-02, Vol.20 (3-4), p.270-274

2013

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Antiplasmodial and antitrypanosomal activity of Triclisia sacleuxii (Pierre) Diels

Phytomedicine (Stuttgart), 2008-09, Vol.15 (9), p.728-733

2008

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Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase: structure, catalytic mechanism and targeted inhibitor design

FEBS letters, 1998-03, Vol.424 (3), p.131-135

1998

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Structure, function, and biogenesis of glycosomes in kinetoplastida

Journal of bioenergetics and biomembranes, 1994-04, Vol.26 (2), p.205-212

1994

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Glycolysis as a target for the design of new anti-trypanosome drugs

Drug resistance updates, 2001-02, Vol.4 (1), p.50-65

2001

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Sulphate Removal Induces a Major Conformational Change in Leishmania mexicana Pyruvate Kinase in the Crystalline State

Journal of molecular biology, 2008-11, Vol.383 (3), p.615-626

2008

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The evolution of kinetoplastid glycosomes

Journal of bioenergetics and biomembranes, 1994-04, Vol.26 (2), p.213-219

1994

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Metabolic Aspects of Glycosomes in Trypanosomatidae – New Data and Views

Parasitology Today, 2000-11, Vol.16 (11), p.482-489

2000

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Experimental and in Silico Analyses of Glycolytic Flux Control in Bloodstream Form Trypanosoma brucei

The Journal of biological chemistry, 2005-08, Vol.280 (31), p.28306-28315

2005

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Glycosomal Glyceraldehyde-3-phosphate Dehydrogenase of Trypanosoma brucei and Trypanosoma cruzi: Expression in Escherichia coli, Purification, and Characterization of the Enzymes

Protein expression and purification, 1995-06, Vol.6 (3), p.244-250

1995

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The Crystal Structure of Trypanosoma brucei Enolase: Visualisation of the Inhibitory Metal Binding Site III and Potential as Target for Selective, Irreversible Inhibition

Journal of molecular biology, 2003-08, Vol.331 (3), p.653-665

2003

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Enolase from Trypanosoma brucei, from the amitochondriate protist Mastigamoeba balamuthi, and from the chloroplast and cytosol of Euglena gracilis: pieces in the evolutionary puzzle of the eukaryotic glycolytic pathway

Molecular biology and evolution, 2000-07, Vol.17 (7), p.989-1000

2000

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Comparison and evolutionary analysis of the glycosomal glyceraldehyde-3-phosphate dehydrogenase from different Kinetoplastida

Journal of molecular evolution, 1998-12, Vol.47 (6), p.728-738

1998

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Cloning and analysis of the gene for the major outer membrane lipoprotein from Pseudomonas aeruginosa

Molecular microbiology, 1989-03, Vol.3 (3), p.421-428

1989

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Organization, structure and evolutionary aspects of genes in trypanosomes

Biochemical Society transactions, 1990-10, Vol.18 (5), p.727-729

1990

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The putative effector-binding site of Leishmania mexicana pyruvate kinase studied by site-directed mutagenesis

FEBS letters, 2002-03, Vol.514 (2), p.255-259

2002

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Kinetic characterization, structure modelling studies and crystallization of Trypanosoma brucei enolase

European journal of biochemistry, 2003-08, Vol.270 (15), p.3205-3213

2003

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Synthesis, spectrometric characterization and trypanocidal activity of some 1,3,4-thiadiazolines derivatives

International Journal of Biological and Chemical Sciences, 2011-03, Vol.4 (6)

2011

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Selective Inhibition of Trypanosomal Glyceraldehyde-3-phosphate Dehydrogenase by Protein Structure-Based Design: Toward New Drugs for the Treatment of Sleeping Sickness

Journal of medicinal chemistry, 1994-10, Vol.37 (21), p.3605-3613

1994

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The rational design of trypanocidal drugs: selective inhibition of the glyceraldehyde-3-phosphate dehydrogenase in Trypanosomatidae

Annals of tropical medicine and parasitology, 1995-12, Vol.89 (sup1), p.23-30

1995

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Leishmania donovani phosphofructokinase: Gene characterization, biochemical properties and structure‐modelling studies

European journal of biochemistry, 2002-08, Vol.269 (16), p.3978-3989

2002

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Molecular analysis of glyceraldehyde-3-phosphate dehydrogenase in Trypanoplasma borelli: an evolutionary scenario of subcellular compartmentation in kinetoplastida

Journal of molecular evolution, 1995-04, Vol.40 (4), p.443-454

1995

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Molecular analysis of glyceraldehyde-3-phosphate dehydrogenase in Trypanoplasma borelli: An evolutionary scenario of subcellular compartmentation in Kinetoplastida

Journal of molecular evolution, 1995-04, Vol.40 (4), p.443-454

1995

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Molecular analysis of the cytosolic and glycosomal glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicana

Molecular and biochemical parasitology, 1992-10, Vol.55 (1), p.115-126

1992

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Crystal structure of Trypanosoma cruzi glyceraldehyde‐3‐phosphate dehydrogenase complexed with an analogue of 1,3‐bisphospho‐d‐glyceric acid

European journal of biochemistry, 2003-11, Vol.270 (22), p.4574-4586

2003

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Antitrypanosomal compounds from the essential oil and extracts of Keetia leucantha leaves with inhibitor activity on Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase

Antiplasmodial and antitrypanosomal activity of Triclisia sacleuxii (Pierre) Diels

Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase: structure, catalytic mechanism and targeted inhibitor design

Structure, function, and biogenesis of glycosomes in kinetoplastida

Glycolysis as a target for the design of new anti-trypanosome drugs

Sulphate Removal Induces a Major Conformational Change in Leishmania mexicana Pyruvate Kinase in the Crystalline State

The evolution of kinetoplastid glycosomes

Metabolic Aspects of Glycosomes in Trypanosomatidae – New Data and Views

Experimental and in Silico Analyses of Glycolytic Flux Control in Bloodstream Form Trypanosoma brucei

Glycosomal Glyceraldehyde-3-phosphate Dehydrogenase of Trypanosoma brucei and Trypanosoma cruzi: Expression in Escherichia coli, Purification, and Characterization of the Enzymes

The Crystal Structure of Trypanosoma brucei Enolase: Visualisation of the Inhibitory Metal Binding Site III and Potential as Target for Selective, Irreversible Inhibition

Enolase from Trypanosoma brucei, from the amitochondriate protist Mastigamoeba balamuthi, and from the chloroplast and cytosol of Euglena gracilis: pieces in the evolutionary puzzle of the eukaryotic glycolytic pathway

Comparison and evolutionary analysis of the glycosomal glyceraldehyde-3-phosphate dehydrogenase from different Kinetoplastida

Cloning and analysis of the gene for the major outer membrane lipoprotein from Pseudomonas aeruginosa

Organization, structure and evolutionary aspects of genes in trypanosomes

The putative effector-binding site of Leishmania mexicana pyruvate kinase studied by site-directed mutagenesis

Kinetic characterization, structure modelling studies and crystallization of Trypanosoma brucei enolase

Synthesis, spectrometric characterization and trypanocidal activity of some 1,3,4-thiadiazolines derivatives

Selective Inhibition of Trypanosomal Glyceraldehyde-3-phosphate Dehydrogenase by Protein Structure-Based Design: Toward New Drugs for the Treatment of Sleeping Sickness

The rational design of trypanocidal drugs: selective inhibition of the glyceraldehyde-3-phosphate dehydrogenase in Trypanosomatidae

Leishmania donovani phosphofructokinase: Gene characterization, biochemical properties and structure‐modelling studies

Molecular analysis of glyceraldehyde-3-phosphate dehydrogenase in Trypanoplasma borelli: an evolutionary scenario of subcellular compartmentation in kinetoplastida

Molecular analysis of glyceraldehyde-3-phosphate dehydrogenase in Trypanoplasma borelli: An evolutionary scenario of subcellular compartmentation in Kinetoplastida

Molecular analysis of the cytosolic and glycosomal glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicana

Crystal structure of Trypanosoma cruzi glyceraldehyde‐3‐phosphate dehydrogenase complexed with an analogue of 1,3‐bisphospho‐d‐glyceric acid

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