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The mercapturic acid pathway

Critical reviews in toxicology, 2019-11, Vol.49 (10), p.819-929

2019

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The Prevalence of GNAS Deficiency-Related Diseases in a Large Cohort of Patients Characterized by the EuroPHP Network

The journal of clinical endocrinology and metabolism, 2016-10, Vol.101 (10), p.3657-3668

2016

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Isoform-Selective Inactivation of Human Arylamine N-Acetyltransferases by Reactive Metabolites of Carcinogenic Arylamines

Chemical research in toxicology, 2009-12, Vol.22 (12), p.1962-1974

2009

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Substantially Delayed Maturation of Growth Plate Chondrocytes in "Humanized" PTH1R Mice with the H223R Mutation of Jansen's Disease

JBMR plus, 2023-10, Vol.7 (10), p.e10802-n/a

2023

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Human Arylamine N-Acetyltransferase 1: In Vitro and Intracellular Inactivation by Nitrosoarene Metabolites of Toxic and Carcinogenic Arylamines

Chemical research in toxicology, 2008-10, Vol.21 (10), p.2005-2016

2008

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NMR-based Model Reveals the Structural Determinants of Mammalian Arylamine N-Acetyltransferase Substrate Specificity

Journal of molecular biology, 2006-10, Vol.363 (1), p.188-200

2006

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Probing the Mechanism of Hamster Arylamine N-Acetyltransferase 2 Acetylation by Active Site Modification, Site-Directed Mutagenesis, and Pre-Steady State and Steady State Kinetic Studies

Biochemistry (Easton), 2004-06, Vol.43 (25), p.8234-8246

2004

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Arylamine N-acetyltransferase I

The international journal of biochemistry & cell biology, 2007, Vol.39 (11), p.1999-2005

2007

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Eukaryotic arylamine N-acetyltransferase. Investigation of substrate specificity by high-throughput screening

Biochemical pharmacology, 2005-01, Vol.69 (2), p.347

2005

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Arylamine N-Acetyltransferases: Characterization of the Substrate Specificities and Molecular Interactions of Environmental Arylamines with Human NAT1 and NAT2

Chemical research in toxicology, 2007-09, Vol.20 (9), p.1300-1308

2007

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Catalytic Mechanism of Hamster Arylamine N-Acetyltransferase 2

Biochemistry (Easton), 2005-08, Vol.44 (33), p.11295-11306

2005

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Arylamine N-acetyltransferase Aggregation and Constitutive Ubiquitylation

Journal of molecular biology, 2006-08, Vol.361 (3), p.482-492

2006

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Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190

The FEBS journal, 2009-12, Vol.276 (23), p.6928-6941

2009

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A Novel Familial PHP1B Variant With Incomplete Loss of Methylation at GNAS-A/B and Enhanced Methylation at GNAS-AS2

The journal of clinical endocrinology and metabolism, 2021-09, Vol.106 (9), p.2779-2787

2021

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Autosomal Dominant Fanconi Syndrome and CKD Associated With Glycine Amidinotransferase Mutation: A Rare Genetic Syndrome: SA-PO528

Journal of the American Society of Nephrology, 2022-11, Vol.33 (11S), p.750-750

2022

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Targeted Long‐Read Sequencing Identifies a Retrotransposon Insertion as a Cause of Altered GNAS Exon A/B Methylation in a Family With Autosomal Dominant Pseudohypoparathyroidism Type 1b (PHP1B)

Journal of bone and mineral research, 2022-09, Vol.37 (9), p.1711-1719

2022

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P059 Wellbeing and shielding of patients with rheumatic disease on biologic therapy during the early COVID-19 pandemic: a single centre experience

Rheumatology (Oxford, England), 2021-04, Vol.60 (Supplement_1)

2021

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Progression of PTH Resistance in Autosomal Dominant Pseudohypoparathyroidism Type Ib Due to Maternal STX16 Deletions

The journal of clinical endocrinology and metabolism, 2022-02, Vol.107 (2), p.e681-e687

2022

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Irreversible Inactivation of Arylamine N-Acetyltransferases in the Presence of N-Hydroxy-4-Acetylaminobiphenyl: A Comparison of Human and Hamster Enzymes

Chemical research in toxicology, 2005-02, Vol.18 (2), p.183-197

2005

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From pseudohypoparathyroidism to inactivating PTH/PTHrP signalling disorder (iPPSD), a novel classification proposed by the EuroPHP network

European journal of endocrinology, 2016-12, Vol.175 (6), p.P1-P17

2016

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Mass Spectrometric Investigation of the Mechanism of Inactivation of Hamster Arylamine N-Acetyltransferase 1 by N-Hydroxy-2-Acetylaminofluorene

Chemical research in toxicology, 2004-03, Vol.17 (3), p.275-286

2004

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Rising Costs of Universities and the Impact on Teaching Effectiveness and Student Outcomes

Hanna, Patrick H

2023

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Inactivating PTH/PTHrP signaling disorders (iPPSDs): evaluation of the new classification in a multicenter large series of 544 molecularly characterized patients

European journal of endocrinology, 2021-02, Vol.184 (2), p.311-320

2021

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Inference of serious harm in the context of online publications past their peak and after the public interest defence falls away: Banks v Cadwalladr

The journal of media law, 2023-01, Vol.15 (1), p.23-38

Hanna, Mark Patrick

2023

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The ‘chilling effect’ of defamation law in Northern Ireland? A comparison with England and Wales in relation to the presumption of jury trial, the threshold of seriousness and the public interest defence

Northern Ireland legal quarterly, 2022-11, Vol.73 (3), p.440-473

Hanna, Mark Patrick

2022

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The mercapturic acid pathway

The Prevalence of GNAS Deficiency-Related Diseases in a Large Cohort of Patients Characterized by the EuroPHP Network

Isoform-Selective Inactivation of Human Arylamine N-Acetyltransferases by Reactive Metabolites of Carcinogenic Arylamines

Substantially Delayed Maturation of Growth Plate Chondrocytes in "Humanized" PTH1R Mice with the H223R Mutation of Jansen's Disease

Human Arylamine N-Acetyltransferase 1: In Vitro and Intracellular Inactivation by Nitrosoarene Metabolites of Toxic and Carcinogenic Arylamines

NMR-based Model Reveals the Structural Determinants of Mammalian Arylamine N-Acetyltransferase Substrate Specificity

Probing the Mechanism of Hamster Arylamine N-Acetyltransferase 2 Acetylation by Active Site Modification, Site-Directed Mutagenesis, and Pre-Steady State and Steady State Kinetic Studies

Arylamine N-acetyltransferase I

Eukaryotic arylamine N-acetyltransferase. Investigation of substrate specificity by high-throughput screening

Arylamine N-Acetyltransferases: Characterization of the Substrate Specificities and Molecular Interactions of Environmental Arylamines with Human NAT1 and NAT2

Catalytic Mechanism of Hamster Arylamine N-Acetyltransferase 2

Arylamine N-acetyltransferase Aggregation and Constitutive Ubiquitylation

Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190

A Novel Familial PHP1B Variant With Incomplete Loss of Methylation at GNAS-A/B and Enhanced Methylation at GNAS-AS2

Autosomal Dominant Fanconi Syndrome and CKD Associated With Glycine Amidinotransferase Mutation: A Rare Genetic Syndrome: SA-PO528

Targeted Long‐Read Sequencing Identifies a Retrotransposon Insertion as a Cause of Altered GNAS Exon A/B Methylation in a Family With Autosomal Dominant Pseudohypoparathyroidism Type 1b (PHP1B)

P059 Wellbeing and shielding of patients with rheumatic disease on biologic therapy during the early COVID-19 pandemic: a single centre experience

Progression of PTH Resistance in Autosomal Dominant Pseudohypoparathyroidism Type Ib Due to Maternal STX16 Deletions

Irreversible Inactivation of Arylamine N-Acetyltransferases in the Presence of N-Hydroxy-4-Acetylaminobiphenyl: A Comparison of Human and Hamster Enzymes

From pseudohypoparathyroidism to inactivating PTH/PTHrP signalling disorder (iPPSD), a novel classification proposed by the EuroPHP network

Mass Spectrometric Investigation of the Mechanism of Inactivation of Hamster Arylamine N-Acetyltransferase 1 by N-Hydroxy-2-Acetylaminofluorene

Rising Costs of Universities and the Impact on Teaching Effectiveness and Student Outcomes

Inactivating PTH/PTHrP signaling disorders (iPPSDs): evaluation of the new classification in a multicenter large series of 544 molecularly characterized patients

Inference of serious harm in the context of online publications past their peak and after the public interest defence falls away: Banks v Cadwalladr

The ‘chilling effect’ of defamation law in Northern Ireland? A comparison with England and Wales in relation to the presumption of jury trial, the threshold of seriousness and the public interest defence

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