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Discovery of α‑Amidobenzylboronates as Highly Potent Covalent Inhibitors of Plasma Kallikrein

ACS medicinal chemistry letters, 2024-04, Vol.15 (4), p.501-509

2024

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Pharmacological suppression of the kallikrein kinin system with KVD900: An orally available plasma kallikrein inhibitor for the on‐demand treatment of hereditary angioedema

Clinical and experimental allergy, 2022-09, Vol.52 (9), p.1059-1070

2022

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KVD900, an oral on-demand treatment for hereditary angioedema: Phase 1 study results

Journal of allergy and clinical immunology, 2022-06, Vol.149 (6), p.2034-2042

2022

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Oral FXIIa inhibitor KV998086 suppresses FXIIa and single chain FXII mediated kallikrein kinin system activation

Frontiers in pharmacology, 2023-12, Vol.14, p.1287487-1287487

2023

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Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedema

Journal of medicinal chemistry, 2022-10, Vol.65 (20), p.13629-13644

2022

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KVD900 as a Single Dose, Rapid, Oral Plasma Kallikrein Inhibitor for the On-Demand Treatment of Hereditary Angioedema Attacks: Pharmacokinetic and Pharmacodynamic results from a Phase 1 Single Ascending Dose Study

Journal of allergy and clinical immunology, 2019-02, Vol.143 (2), p.AB39-AB39

2019

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Genetic interventions in mammalian cells; applications and uses in high-throughput screening and drug discovery

Cell biology and toxicology, 2010-02, Vol.26 (1), p.43-55

2010

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New Benzylureas as a Novel Series of Potent, Nonpeptidic Vasopressin V2 Receptor Agonists

Journal of medicinal chemistry, 2008-12, Vol.51 (24), p.8124-8134

2008

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Rapid Plasma Kallikrein Inhibition Following Oral KVD900 is Associated With Early Symptom Relief in Patients With Hereditary Angioedema

Journal of allergy and clinical immunology, 2022-02, Vol.149 (2), p.AB167-AB167

2022

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Reading and writing grade by grade: Rev. ed

2009

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Using rubrics to improve student writing, grade 5: Rev. ed

2009

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Using rubrics to improve student writing, grade 2: Rev. ed

2009

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Using rubrics to improve student writing, grade 4: Rev. ed

2009

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Using rubrics to improve student writing, grade 3: Rev. ed

2009

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Using rubrics to improve student writing, kindergarten: Rev. ed

2009

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Using rubrics to improve student writing, grade 1: Rev. ed

2009

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Reading and writing with understanding: Comprehension in fourth and fifth grades

2009

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Children Doing the Business of Schools (Integrating Curriculum)

The Reading teacher, 1995, Vol.48 (4), p.350

Hampton, Sally

1995

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Integrating curriculum: Children doing the business of scho

The Reading teacher, 1994-12, Vol.48 (4), p.350

Hampton, Sally

1994

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Children doing the business of schools

The Reading teacher, 1994-12, Vol.48 (4), p.350

Hampton, Sally

1994

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Restructuring Curriculum for "Real-World" Experiences

Educational horizons, 1996-07, Vol.74 (4), p.187-191

1996

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National performance standards for oral communication k-12: New standards and speaking/listening/viewing

Communication education, 1998-04, Vol.47 (2), p.183-193

1998

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Integrating Curriculum

The Reading teacher, 1994-12, Vol.48 (4), p.350-353

1994

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Report: The Keystone Project

Quarterly of the National Writing Project and the Center for the Study of Writing, 1988, Vol.10 (3), p.26

Hampton, Sally

1988

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A Further Word: The Teaching of Writing. Grades K-5

Hampton, Sally

1989

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Discovery of α‑Amidobenzylboronates as Highly Potent Covalent Inhibitors of Plasma Kallikrein

Pharmacological suppression of the kallikrein kinin system with KVD900: An orally available plasma kallikrein inhibitor for the on‐demand treatment of hereditary angioedema

KVD900, an oral on-demand treatment for hereditary angioedema: Phase 1 study results

Oral FXIIa inhibitor KV998086 suppresses FXIIa and single chain FXII mediated kallikrein kinin system activation

Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedema

KVD900 as a Single Dose, Rapid, Oral Plasma Kallikrein Inhibitor for the On-Demand Treatment of Hereditary Angioedema Attacks: Pharmacokinetic and Pharmacodynamic results from a Phase 1 Single Ascending Dose Study

Genetic interventions in mammalian cells; applications and uses in high-throughput screening and drug discovery

New Benzylureas as a Novel Series of Potent, Nonpeptidic Vasopressin V2 Receptor Agonists

Rapid Plasma Kallikrein Inhibition Following Oral KVD900 is Associated With Early Symptom Relief in Patients With Hereditary Angioedema

Reading and writing grade by grade: Rev. ed

Using rubrics to improve student writing, grade 5: Rev. ed

Using rubrics to improve student writing, grade 2: Rev. ed

Using rubrics to improve student writing, grade 4: Rev. ed

Using rubrics to improve student writing, grade 3: Rev. ed

Using rubrics to improve student writing, kindergarten: Rev. ed

Using rubrics to improve student writing, grade 1: Rev. ed

Reading and writing with understanding: Comprehension in fourth and fifth grades

Children Doing the Business of Schools (Integrating Curriculum)

Integrating curriculum: Children doing the business of scho

Children doing the business of schools

Restructuring Curriculum for "Real-World" Experiences

National performance standards for oral communication k-12: New standards and speaking/listening/viewing

Integrating Curriculum

Report: The Keystone Project

A Further Word: The Teaching of Writing. Grades K-5

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