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Novel roles of phosphoinositides in signaling, lipid transport, and disease

Current opinion in cell biology, 2020-04, Vol.63, p.57-67

2020

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A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi

The Journal of cell biology, 2014-04, Vol.205 (1), p.113-126

2014

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Membrane Biology: Making Light Work of Lipids

Current biology, 2012-10, Vol.22 (20), p.R869-R871

Hammond, Gerald R.V.

2012

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Probing the subcellular distribution of phosphatidylinositol reveals a surprising lack at the plasma membrane

The Journal of cell biology, 2020-03, Vol.219 (3), p.1

2020

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PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites

The Journal of cell biology, 2018-05, Vol.217 (5), p.1797-1813

2018

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A high-avidity biosensor reveals plasma membrane PI(3,4)P2 is predominantly a class I PI3K signaling product

The Journal of cell biology, 2019-03, Vol.218 (3), p.1066-1079

2019

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Regulation of voltage-gated potassium channels by PI(4,5)P2

The Journal of general physiology, 2012-08, Vol.140 (2), p.189-205

2012

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Quantification of Genetically Encoded Lipid Biosensors

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2251, p.55

2021

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Induced Dimerization Tools to Deplete Specific Phosphatidylinositol Phosphates

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2251, p.105

2021

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A conserved polybasic domain mediates plasma membrane targeting of Lgl and its regulation by hypoxia

The Journal of cell biology, 2015-10, Vol.211 (2), p.273-286

2015

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Reversible binding and rapid diffusion of proteins in complex with inositol lipids serves to coordinate free movement with spatial information

The Journal of cell biology, 2009-01, Vol.184 (2), p.297-308

2009

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Polyphosphoinositide binding domains: Key to inositol lipid biology

Biochimica et biophysica acta, 2015-06, Vol.1851 (6), p.746-758

2015

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Beyond PI3Ks: targeting phosphoinositide kinases in disease

Nature reviews. Drug discovery, 2023-05, Vol.22 (5), p.357-386

2023

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Polyphosphoinositol lipids: Under‐PPInning synaptic function in health and disease

Developmental neurobiology (Hoboken, N.J.), 2007-08, Vol.67 (9), p.1232-1247

2007

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PI(4,5)P2: signaling the plasma membrane

Biochemical journal, 2022-11, Vol.479 (21), p.2311-2325

2022

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PI4P and PI(4,5)P2 Are Essential But Independent Lipid Determinants of Membrane Identity

Science (American Association for the Advancement of Science), 2012-08, Vol.337 (6095), p.727-730

2012

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Molding a PI(3,5)P2 biosensor

The Journal of cell biology, 2023-09, Vol.222 (9), p.1

2023

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Does PtdIns(4,5) P 2 concentrate so it can multi-task?

Biochemical Society transactions, 2016-02, Vol.44 (1), p.228-233

Hammond, Gerald R.V.

2016

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TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes

Nature communications, 2017-11, Vol.8 (1), p.1580-17, Article 1580

2017

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Genetically encoded lipid biosensors

Molecular biology of the cell, 2018-07, Vol.29 (13), p.1526-1532

2018

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Lysosomal inhibition sensitizes TMEM16A-expressing cancer cells to chemotherapy

Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (12), p.e2100670119-e2100670119

2022

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Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P2

Biochemical journal, 2009-07, Vol.422 (1), p.23-35

2009

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Does PtdIns(4,5)P2 concentrate so it can multi-task?

Biochemical Society transactions, 2016-02, Vol.44 (1), p.228

Hammond, Gerald R V

2016

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SAC1 degrades its lipid substrate PtdIns4P in the endoplasmic reticulum to maintain a steep chemical gradient with donor membranes

eLife, 2018-02, Vol.7

2018

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Oxysterol Binding Protein: Tether, Transporter… and Flux Capacitor?

Trends in cell biology, 2019-07, Vol.29 (7), p.531-533

2019

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Novel roles of phosphoinositides in signaling, lipid transport, and disease

A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi

Membrane Biology: Making Light Work of Lipids

Probing the subcellular distribution of phosphatidylinositol reveals a surprising lack at the plasma membrane

PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites

A high-avidity biosensor reveals plasma membrane PI(3,4)P2 is predominantly a class I PI3K signaling product

Regulation of voltage-gated potassium channels by PI(4,5)P2

Quantification of Genetically Encoded Lipid Biosensors

Induced Dimerization Tools to Deplete Specific Phosphatidylinositol Phosphates

A conserved polybasic domain mediates plasma membrane targeting of Lgl and its regulation by hypoxia

Reversible binding and rapid diffusion of proteins in complex with inositol lipids serves to coordinate free movement with spatial information

Polyphosphoinositide binding domains: Key to inositol lipid biology

Beyond PI3Ks: targeting phosphoinositide kinases in disease

Polyphosphoinositol lipids: Under‐PPInning synaptic function in health and disease

PI(4,5)P2: signaling the plasma membrane

PI4P and PI(4,5)P2 Are Essential But Independent Lipid Determinants of Membrane Identity

Molding a PI(3,5)P2 biosensor

Does PtdIns(4,5) P 2 concentrate so it can multi-task?

TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes

Genetically encoded lipid biosensors

Lysosomal inhibition sensitizes TMEM16A-expressing cancer cells to chemotherapy

Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P2

Does PtdIns(4,5)P2 concentrate so it can multi-task?

SAC1 degrades its lipid substrate PtdIns4P in the endoplasmic reticulum to maintain a steep chemical gradient with donor membranes

Oxysterol Binding Protein: Tether, Transporter… and Flux Capacitor?

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