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Impaired Adipogenesis and Dysfunctional Adipose Tissue in Human Hypertrophic Obesity

Physiological reviews, 2018-10, Vol.98 (4), p.1911-1941

2018

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BMP4 and BMP Antagonists Regulate Human White and Beige Adipogenesis

Diabetes (New York, N.Y.), 2015-05, Vol.64 (5), p.1670-1681

2015

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Inflammation and impaired adipogenesis in hypertrophic obesity in man

American journal of physiology: endocrinology and metabolism, 2009-11, Vol.297 (5), p.E999-E1003

2009

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Genetic predisposition for Type 2 diabetes, but not for overweight/obesity, is associated with a restricted adipogenesis

PloS one, 2011-04, Vol.6 (4), p.e18284-e18284

2011

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The Novel Secreted Adipokine WNT1-inducible Signaling Pathway Protein 2 (WISP2) Is a Mesenchymal Cell Activator of Canonical WNT

The Journal of biological chemistry, 2014-03, Vol.289 (10), p.6899-6907

2014

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WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (7), p.2563-2568

2013

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Adipocyte hypertrophy, inflammation and fibrosis characterize subcutaneous adipose tissue of healthy, non-obese subjects predisposed to type 2 diabetes

PloS one, 2014-08, Vol.9 (8), p.e105262-e105262

2014

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Retinol-Binding Protein 4 Inhibits Insulin Signaling in Adipocytes by Inducing Proinflammatory Cytokines in Macrophages through a c-Jun N-Terminal Kinase- and Toll-Like Receptor 4-Dependent and Retinol-Independent Mechanism

Molecular and Cellular Biology, 2012-05, Vol.32 (10), p.2010-2019

2012

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BMP4 Gene Therapy in Mature Mice Reduces BAT Activation but Protects from Obesity by Browning Subcutaneous Adipose Tissue

Cell reports (Cambridge), 2017-08, Vol.20 (5), p.1038-1049

2017

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Retinol-Binding Protein 4 and Insulin Resistance in Lean, Obese, and Diabetic Subjects

The New England journal of medicine, 2006-06, Vol.354 (24), p.2552-2563

2006

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Adipose tissue morphology, imaging and metabolomics predicting cardiometabolic risk and family history of type 2 diabetes in non-obese men

Scientific reports, 2020-06, Vol.10 (1), p.9973-9973, Article 9973

2020

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Cephalic phase of insulin secretion in response to a meal is unrelated to family history of type 2 diabetes

PloS one, 2017-03, Vol.12 (3), p.e0173654-e0173654

2017

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Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases

International journal of molecular sciences, 2020-01, Vol.21 (2), p.469

2020

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Effects of dapagliflozin and dapagliflozin-saxagliptin on erythropoiesis, iron and inflammation markers in patients with type 2 diabetes and chronic kidney disease: data from the DELIGHT trial

Cardiovascular diabetology, 2023-11, Vol.22 (1), p.330-330, Article 330

2023

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Adipose tissue dysregulation and reduced insulin sensitivity in non-obese individuals with enlarged abdominal adipose cells

Diabetology and metabolic syndrome, 2012-09, Vol.4 (1), p.42-42, Article 42

2012

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Inflamed adipose tissue, insulin resistance and vascular injury

Diabetes/metabolism research and reviews, 2008-11, Vol.24 (8), p.595-603

2008

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Adult mice are unresponsive to AAV8-Gremlin1 gene therapy targeting the liver

PloS one, 2021-02, Vol.16 (2), p.e0247300-e0247300

2021

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Insulin resistance and impaired adipogenesis

Trends in endocrinology and metabolism, 2015-04, Vol.26 (4), p.193-200

2015

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BMP4 gene therapy enhances insulin sensitivity but not adipose tissue browning in obese mice

Molecular metabolism (Germany), 2020-02, Vol.32, p.15-26

2020

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High local concentrations and effects on differentiation implicate interleukin-6 as a paracrine regulator

Obesity (Silver Spring, Md.), 2004-03, Vol.12 (3), p.454-460

2004

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Metabolic characteristics of individuals at a high risk of type 2 diabetes - a comparative cross-sectional study

BMC endocrine disorders, 2017-07, Vol.17 (1), p.40-40, Article 40

2017

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Metabolic predictors of impaired glucose tolerance and type 2 diabetes in a predisposed population--A prospective cohort study

BMC endocrine disorders, 2015-09, Vol.15 (1), p.51-51, Article 51

2015

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Impaired Preadipocyte Differentiation in Human Abdominal Obesity: Role of Wnt, Tumor Necrosis Factor-α, and Inflammation

Diabetes (New York, N.Y.), 2009-07, Vol.58 (7), p.1550-1557

2009

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Restricted Adipogenesis in Hypertrophic Obesity: The Role of WISP2, WNT, and BMP4

Diabetes (New York, N.Y.), 2013-09, Vol.62 (9), p.2997-3004

2013

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A novel cellular marker of insulin resistance and early atherosclerosis in humans is related to impaired fat cell differentiation and low adiponectin

The FASEB journal, 2003-08, Vol.17 (11), p.1434-1440

2003

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Impaired Adipogenesis and Dysfunctional Adipose Tissue in Human Hypertrophic Obesity

BMP4 and BMP Antagonists Regulate Human White and Beige Adipogenesis

Inflammation and impaired adipogenesis in hypertrophic obesity in man

Genetic predisposition for Type 2 diabetes, but not for overweight/obesity, is associated with a restricted adipogenesis

The Novel Secreted Adipokine WNT1-inducible Signaling Pathway Protein 2 (WISP2) Is a Mesenchymal Cell Activator of Canonical WNT

WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4

Adipocyte hypertrophy, inflammation and fibrosis characterize subcutaneous adipose tissue of healthy, non-obese subjects predisposed to type 2 diabetes

Retinol-Binding Protein 4 Inhibits Insulin Signaling in Adipocytes by Inducing Proinflammatory Cytokines in Macrophages through a c-Jun N-Terminal Kinase- and Toll-Like Receptor 4-Dependent and Retinol-Independent Mechanism

BMP4 Gene Therapy in Mature Mice Reduces BAT Activation but Protects from Obesity by Browning Subcutaneous Adipose Tissue

Retinol-Binding Protein 4 and Insulin Resistance in Lean, Obese, and Diabetic Subjects

Adipose tissue morphology, imaging and metabolomics predicting cardiometabolic risk and family history of type 2 diabetes in non-obese men

Cephalic phase of insulin secretion in response to a meal is unrelated to family history of type 2 diabetes

Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases

Effects of dapagliflozin and dapagliflozin-saxagliptin on erythropoiesis, iron and inflammation markers in patients with type 2 diabetes and chronic kidney disease: data from the DELIGHT trial

Adipose tissue dysregulation and reduced insulin sensitivity in non-obese individuals with enlarged abdominal adipose cells

Inflamed adipose tissue, insulin resistance and vascular injury

Adult mice are unresponsive to AAV8-Gremlin1 gene therapy targeting the liver

Insulin resistance and impaired adipogenesis

BMP4 gene therapy enhances insulin sensitivity but not adipose tissue browning in obese mice

High local concentrations and effects on differentiation implicate interleukin-6 as a paracrine regulator

Metabolic characteristics of individuals at a high risk of type 2 diabetes - a comparative cross-sectional study

Metabolic predictors of impaired glucose tolerance and type 2 diabetes in a predisposed population--A prospective cohort study

Impaired Preadipocyte Differentiation in Human Abdominal Obesity: Role of Wnt, Tumor Necrosis Factor-α, and Inflammation

Restricted Adipogenesis in Hypertrophic Obesity: The Role of WISP2, WNT, and BMP4

A novel cellular marker of insulin resistance and early atherosclerosis in humans is related to impaired fat cell differentiation and low adiponectin

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