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Prediction of clinically relevant drug‐induced liver injury from structure using machine learning

Journal of applied toxicology, 2019-03, Vol.39 (3), p.412-419

2019

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Ivermectin to reduce malaria transmission I. Pharmacokinetic and pharmacodynamic considerations regarding efficacy and safety

Malaria journal, 2017-04, Vol.16 (1), p.161-16, Article 161

2017

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Drug-Disease Severity and Target-Disease Severity Interaction Networks in COVID-19 Patients

Pharmaceutics, 2022-08, Vol.14 (9), p.1828

2022

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Computational prediction of blood-brain barrier permeability using decision tree induction

Molecules (Basel, Switzerland), 2012-08, Vol.17 (9), p.10429-10445

2012

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Development and validation of a prognostic COVID-19 severity assessment (COSA) score and machine learning models for patient triage at a tertiary hospital

Journal of translational medicine, 2021-02, Vol.19 (1), p.56-11, Article 56

2021

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Modeling of SARS-CoV-2 Treatment Effects for Informed Drug Repurposing

Frontiers in pharmacology, 2021-03, Vol.12, p.625678

2021

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Pharmacokinetics of ivermectin metabolites and their activity against Anopheles stephensi mosquitoes

Malaria journal, 2023-06, Vol.22 (1), p.194-194, Article 194

2023

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Effectiveness of Antiviral Therapy in Highly-Transmissible Variants of SARS-CoV-2: A Modeling and Simulation Study

Frontiers in pharmacology, 2022-02, Vol.13, p.816429-816429

2022

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The pharmacokinetics and drug-drug interactions of ivermectin in Aedes aegypti mosquitoes

PLoS pathogens, 2021-03, Vol.17 (3), p.e1009382

2021

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Modeling Structure-Activity Relationship of AMPK Activation

Molecules (Basel, Switzerland), 2021-10, Vol.26 (21), p.6508

2021

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Mosquitocidal efficacy and pharmacokinetics of single-dose ivermectin versus three-day dose regimen for malaria vector control compared with albendazole and no treatment: An open-label randomized controlled trial

International journal of infectious diseases, 2024-11, Vol.148, p.107236, Article 107236

2024

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Revalidating the prognostic COVID-19 severity assessment (COSA) score for variants of concern

Journal of translational medicine, 2022-09, Vol.20 (1), p.1-427, Article 427

2022

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Potential metabolic resistance mechanisms to ivermectin in Anopheles gambiae: a synergist bioassay study

Parasites & vectors, 2021-03, Vol.14 (1), p.172-12, Article 172

2021

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Effect of SARS-CoV-2 Infection on Renal and Hepatic Function after NSAID and Paracetamol Therapy

COVID, 2024-07, Vol.4 (7), p.910-920

2024

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UROPOT: study protocol for a randomized, double-blind phase I/II trial for metabolism-based potentiation of antimicrobial prophylaxis in the urological tract

Trials, 2024-10, Vol.25 (1), p.682-10, Article 682

2024

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Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects

Frontiers in pharmacology, 2017-09, Vol.8, p.617-617

2017

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Green tea extract enhances parieto-frontal connectivity during working memory processing

Psychopharmacology, 2014-10, Vol.231 (19), p.3879-3888

2014

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Cytochrome P450/ABC transporter inhibition simultaneously enhances ivermectin pharmacokinetics in the mammal host and pharmacodynamics in Anopheles gambiae

Scientific reports, 2017-08, Vol.7 (1), p.8535-12, Article 8535

2017

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Effects of a fixed herbal drug combination (Ze 185) to an experimental acute stress setting in healthy men – An explorative randomized placebo-controlled double-blind study

Phytomedicine (Stuttgart), 2018-01, Vol.39, p.85-92

2018

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Target Attainment and Population Pharmacokinetics of Cefazolin in Patients with Invasive Staphylococcus aureus Infections: A Prospective Cohort Study

Antibiotics (Basel), 2024-09, Vol.13 (10), p.928

2024

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An automated screening method for drugs and toxic compounds in human serum and urine using liquid chromatography–tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010-10, Vol.878 (28), p.2726-2732

2010

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Classification of Cytochrome P450 Activities Using Machine Learning Methods

Molecular pharmaceutics, 2009-12, Vol.6 (6), p.1920-1926

2009

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Prediction of clinically relevant drug‐induced liver injury from structure using machine learning

Ivermectin to reduce malaria transmission I. Pharmacokinetic and pharmacodynamic considerations regarding efficacy and safety

Drug-Disease Severity and Target-Disease Severity Interaction Networks in COVID-19 Patients

Computational prediction of blood-brain barrier permeability using decision tree induction

Development and validation of a prognostic COVID-19 severity assessment (COSA) score and machine learning models for patient triage at a tertiary hospital

Modeling of SARS-CoV-2 Treatment Effects for Informed Drug Repurposing

Pharmacokinetics of ivermectin metabolites and their activity against Anopheles stephensi mosquitoes

Effectiveness of Antiviral Therapy in Highly-Transmissible Variants of SARS-CoV-2: A Modeling and Simulation Study

The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: A pilot, double-blind, placebo-controlled, randomized clinical trial

The pharmacokinetics and drug-drug interactions of ivermectin in Aedes aegypti mosquitoes

Modeling Structure-Activity Relationship of AMPK Activation

Mosquitocidal efficacy and pharmacokinetics of single-dose ivermectin versus three-day dose regimen for malaria vector control compared with albendazole and no treatment: An open-label randomized controlled trial

Revalidating the prognostic COVID-19 severity assessment (COSA) score for variants of concern

Potential metabolic resistance mechanisms to ivermectin in Anopheles gambiae: a synergist bioassay study

Effect of SARS-CoV-2 Infection on Renal and Hepatic Function after NSAID and Paracetamol Therapy

UROPOT: study protocol for a randomized, double-blind phase I/II trial for metabolism-based potentiation of antimicrobial prophylaxis in the urological tract

Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects

Green tea extract enhances parieto-frontal connectivity during working memory processing

BOHEMIA: Broad One Health Endectocide-based Malaria Intervention in Africa-a phase III cluster-randomized, open-label, clinical trial to study the safety and efficacy of ivermectin mass drug administration to reduce malaria transmission in two African settings

Cytochrome P450/ABC transporter inhibition simultaneously enhances ivermectin pharmacokinetics in the mammal host and pharmacodynamics in Anopheles gambiae

Effects of a fixed herbal drug combination (Ze 185) to an experimental acute stress setting in healthy men – An explorative randomized placebo-controlled double-blind study

The SARS-CoV-2 Ivermectin Navarra-ISGlobal Trial (SAINT) to Evaluate the Potential of Ivermectin to Reduce COVID-19 Transmission in low risk, non-severe COVID-19 patients in the first 48 hours after symptoms onset: A structured summary of a study protocol for a randomized control pilot trial

Target Attainment and Population Pharmacokinetics of Cefazolin in Patients with Invasive Staphylococcus aureus Infections: A Prospective Cohort Study

An automated screening method for drugs and toxic compounds in human serum and urine using liquid chromatography–tandem mass spectrometry

Classification of Cytochrome P450 Activities Using Machine Learning Methods

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