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Heterotrimeric G protein activation by G-protein-coupled receptors

Nature reviews. Molecular cell biology, 2008-01, Vol.9 (1), p.60-71

2008

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Conformational Flexibility and Structural Dynamics in GPCR-Mediated G Protein Activation: A Perspective

Journal of molecular biology, 2013-07, Vol.425 (13), p.2288-2298

2013

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Protease-activated receptor (PAR) 1 and PAR4 differentially regulate factor V expression from human platelets

Molecular pharmacology, 2013-04, Vol.83 (4), p.781-792

2013

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Structural basis of function in heterotrimeric G proteins

Quarterly reviews of biophysics, 2006-05, Vol.39 (2), p.117-166

2006

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Phototransduction in retinal cones: Analysis of parameter importance

PloS one, 2021-10, Vol.16 (10), p.e0258721-e0258721

2021

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The expanding roles and mechanisms of G protein–mediated presynaptic inhibition

The Journal of biological chemistry, 2019-02, Vol.294 (5), p.1661-1670

2019

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Position of rhodopsin photoisomerization on the disk surface confers variability to the rising phase of the single photon response in vertebrate rod photoreceptors

PloS one, 2020-10, Vol.15 (10), p.e0240527

2020

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GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation

Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (17), p.4501-4506

2018

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Heterosynaptic GABAB Receptor Function within Feedforward Microcircuits Gates Glutamatergic Transmission in the Nucleus Accumbens Core

The Journal of neuroscience, 2019-11, Vol.39 (47), p.9277-9293

2019

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Role of protease-activated receptor 4 in mouse models of acute and chronic kidney injury

American journal of physiology. Renal physiology, 2024-02, Vol.326 (2), p.F219

2024

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GPCR mediated regulation of synaptic transmission

Progress in neurobiology, 2012-03, Vol.96 (3), p.304-321

2012

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Physiological roles for neuromodulation via Gi/o GPCRs working through Gβγ–SNARE interaction

Neuropsychopharmacology (New York, N.Y.), 2020-01, Vol.45 (1), p.221-221

2020

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Gβγ-SNAP25 exocytotic brake removal enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity

The Journal of clinical investigation, 2023-10, Vol.133 (19), p.1-19

2023

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Disabling Gβγ-SNAP-25 interaction in gene-targeted mice results in enhancement of long-term potentiation at Schaffer collateral-CA1 synapses in the hippocampus

Neuroreport, 2019-07, Vol.30 (10), p.695

2019

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Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (23), p.9420-9424

2011

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Presynaptic mechanisms underlying GABAB-receptor-mediated inhibition of spontaneous neurotransmitter release

Cell reports (Cambridge), 2022-01, Vol.38 (3), p.110255-110255, Article 110255

2022

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SNAP25 differentially contributes to Gi/o-coupled receptor function at glutamatergic synapses in the nucleus accumbens

Frontiers in cellular neuroscience, 2023-05, Vol.17, p.1165261-1165261

2023

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The role of coagulation and platelets in colon cancer-associated thrombosis

American Journal of Physiology: Cell Physiology, 2019-02, Vol.316 (2), p.C264-C273

2019

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The in vivo specificity of synaptic Gβ and Gγ subunits to the α2a adrenergic receptor at CNS synapses

Scientific reports, 2019-02, Vol.9 (1), p.1718-1718, Article 1718

2019

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Rhodopsin expression level affects rod outer segment morphology and photoresponse kinetics

PloS one, 2012-05, Vol.7 (5), p.e37832-e37832

2012

Volltextzugriff (PDF)

G Protein Preassembly Rescues Efficacy of W 6.48 Toggle Mutations in Neuropeptide Y 2 Receptor

Molecular pharmacology, 2018-04, Vol.93 (4), p.387-401

2018

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Elevated protease-activated receptor 4 (PAR4) gene expression in Alzheimer’s disease predicts cognitive decline

Neurobiology of aging, 2024-08, Vol.140, p.93-101

2024

Volltextzugriff (PDF)

Gpr125 modulates Dishevelled distribution and planar cell polarity signaling

Development (Cambridge), 2013-07, Vol.140 (14), p.3028-3039

2013

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Synthesis of indole derived protease-activated receptor 4 antagonists and characterization in human platelets

PloS one, 2013-06, Vol.8 (6), p.e65528-e65528

2013

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Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release

Nature structural & molecular biology, 2014-01, Vol.21 (1), p.56

2014

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Heterotrimeric G protein activation by G-protein-coupled receptors

Conformational Flexibility and Structural Dynamics in GPCR-Mediated G Protein Activation: A Perspective

Protease-activated receptor (PAR) 1 and PAR4 differentially regulate factor V expression from human platelets

Structural basis of function in heterotrimeric G proteins

Phototransduction in retinal cones: Analysis of parameter importance

The expanding roles and mechanisms of G protein–mediated presynaptic inhibition

Position of rhodopsin photoisomerization on the disk surface confers variability to the rising phase of the single photon response in vertebrate rod photoreceptors

GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation

Heterosynaptic GABAB Receptor Function within Feedforward Microcircuits Gates Glutamatergic Transmission in the Nucleus Accumbens Core

Role of protease-activated receptor 4 in mouse models of acute and chronic kidney injury

GPCR mediated regulation of synaptic transmission

Physiological roles for neuromodulation via Gi/o GPCRs working through Gβγ–SNARE interaction

Gβγ-SNAP25 exocytotic brake removal enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity

Disabling Gβγ-SNAP-25 interaction in gene-targeted mice results in enhancement of long-term potentiation at Schaffer collateral-CA1 synapses in the hippocampus

Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit

Presynaptic mechanisms underlying GABAB-receptor-mediated inhibition of spontaneous neurotransmitter release

SNAP25 differentially contributes to Gi/o-coupled receptor function at glutamatergic synapses in the nucleus accumbens

The role of coagulation and platelets in colon cancer-associated thrombosis

The in vivo specificity of synaptic Gβ and Gγ subunits to the α2a adrenergic receptor at CNS synapses

Rhodopsin expression level affects rod outer segment morphology and photoresponse kinetics

G Protein Preassembly Rescues Efficacy of W 6.48 Toggle Mutations in Neuropeptide Y 2 Receptor

Elevated protease-activated receptor 4 (PAR4) gene expression in Alzheimer’s disease predicts cognitive decline

Gpr125 modulates Dishevelled distribution and planar cell polarity signaling

Synthesis of indole derived protease-activated receptor 4 antagonists and characterization in human platelets

Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release

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