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Mechanisms of ENaC Regulation and Clinical Implications

Journal of the American Society of Nephrology, 2008-10, Vol.19 (10), p.1845-1854

2008

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Oral delivery of metformin by chitosan nanoparticles for polycystic kidney disease

Journal of controlled release, 2021-01, Vol.329, p.1198-1209

2021

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Metformin improves relevant disease parameters in an autosomal dominant polycystic kidney disease mouse model

American journal of physiology. Renal physiology, 2022-01, Vol.322 (1), p.F27-F41

2022

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Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

Cell, 2010-07, Vol.142 (2), p.270-283

2010

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Role of AMP-activated protein kinase in kidney tubular transport, metabolism, and disease

Current opinion in nephrology and hypertension, 2017-09, Vol.26 (5), p.375-383

2017

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AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System

Molecular cell, 2020-03, Vol.77 (5), p.951-969.e9

2020

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MIF Matters: The Macrophage Migration Inhibitory Factor and Kidney Injury

American journal of kidney diseases, 2019-03, Vol.73 (3), p.429-431

2019

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Primary results of the randomized trial of metformin administration in polycystic kidney disease (TAME PKD)

Kidney international, 2021-09, Vol.100 (3), p.684-696

2021

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Noncanonical Control of Vasopressin Receptor Type 2 Signaling by Retromer and Arrestin

The Journal of biological chemistry, 2013-09, Vol.288 (39), p.27849-27860

2013

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Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors

Nature communications, 2021-06, Vol.12 (1), p.3641-3641, Article 3641

2021

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A Randomized Clinical Trial of Metformin to Treat Autosomal Dominant Polycystic Kidney Disease

American journal of nephrology, 2018-01, Vol.47 (5), p.352-360

2018

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"First do no harm": kidney drug targeting to avoid toxicity in ADPKD

American journal of physiology. Renal physiology, 2018-09, Vol.315 (3), p.F535-F536

2018

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Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis

Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (6), p.2462-2467

2011

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Design and in vivo characterization of kidney-targeting multimodal micelles for renal drug delivery

Nano research, 2018-10, Vol.11 (10), p.5584-5595

2018

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Investigation of Basolateral Targeting Micelles for Drug Delivery Applications in Polycystic Kidney Disease

Biomacromolecules, 2024-05, Vol.25 (5), p.2749-2761

2024

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Extracorporeal Therapy for Dabigatran Removal in the Treatment of Acute Bleeding: A Single Center Experience

Clinical journal of the American Society of Nephrology, 2013-09, Vol.8 (9), p.1533-1539

2013

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AMPK phosphorylation of the β1Pix exchange factor regulates the assembly and function of an ENaC inhibitory complex in kidney epithelial cells

American journal of physiology. Renal physiology, 2019-12, Vol.317 (6), p.F1513-F1525

2019

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In vitro delivery of mTOR inhibitors by kidney-targeted micelles for autosomal dominant polycystic kidney disease

SLAS technology, 2023-08, Vol.28 (4), p.223-229

2023

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Activation of AMP‐activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic fitness

The FASEB journal, 2020-05, Vol.34 (5), p.7036-7057

2020

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Role of the energy sensor AMP-activated protein kinase in renal physiology and disease

American Journal of Physiology - Renal Physiology, 2010-05, Vol.298 (5), p.F1067-F1077

2010

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Female Protection Against Diabetic Kidney Disease Is Regulated by Kidney-Specific AMPK Activity

Diabetes (New York, N.Y.), 2024-07, Vol.73 (7), p.1167-1177

2024

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Interactions between HIF-1α and AMPK in the regulation of cellular hypoxia adaptation in chronic kidney disease

American journal of physiology. Renal physiology, 2015-09, Vol.309 (5), p.F414-F428

2015

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Effects of Hydrochlorothiazide and Metformin on Aquaresis and Nephroprotection by a Vasopressin V2 Receptor Antagonist in ADPKD: A Randomized Crossover Trial

Clinical journal of the American Society of Nephrology, 2022-04, Vol.17 (4), p.507-517

2022

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Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action

The Journal of clinical investigation, 2015-09, Vol.125 (9), p.3433-3448

2015

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Septic acute kidney injury: molecular mechanisms and the importance of stratification and targeting therapy

Critical care (London, England), 2014-09, Vol.18 (5), p.501-501, Article 501

2014

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Mechanisms of ENaC Regulation and Clinical Implications

Oral delivery of metformin by chitosan nanoparticles for polycystic kidney disease

Metformin improves relevant disease parameters in an autosomal dominant polycystic kidney disease mouse model

Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

Role of AMP-activated protein kinase in kidney tubular transport, metabolism, and disease

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System

MIF Matters: The Macrophage Migration Inhibitory Factor and Kidney Injury

Primary results of the randomized trial of metformin administration in polycystic kidney disease (TAME PKD)

Noncanonical Control of Vasopressin Receptor Type 2 Signaling by Retromer and Arrestin

Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors

A Randomized Clinical Trial of Metformin to Treat Autosomal Dominant Polycystic Kidney Disease

"First do no harm": kidney drug targeting to avoid toxicity in ADPKD

Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis

Design and in vivo characterization of kidney-targeting multimodal micelles for renal drug delivery

Investigation of Basolateral Targeting Micelles for Drug Delivery Applications in Polycystic Kidney Disease

Extracorporeal Therapy for Dabigatran Removal in the Treatment of Acute Bleeding: A Single Center Experience

AMPK phosphorylation of the β1Pix exchange factor regulates the assembly and function of an ENaC inhibitory complex in kidney epithelial cells

In vitro delivery of mTOR inhibitors by kidney-targeted micelles for autosomal dominant polycystic kidney disease

Activation of AMP‐activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic fitness

Role of the energy sensor AMP-activated protein kinase in renal physiology and disease

Female Protection Against Diabetic Kidney Disease Is Regulated by Kidney-Specific AMPK Activity

Interactions between HIF-1α and AMPK in the regulation of cellular hypoxia adaptation in chronic kidney disease

Effects of Hydrochlorothiazide and Metformin on Aquaresis and Nephroprotection by a Vasopressin V2 Receptor Antagonist in ADPKD: A Randomized Crossover Trial

Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action

Septic acute kidney injury: molecular mechanisms and the importance of stratification and targeting therapy

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