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Radium-223 Inhibits Osseous Prostate Cancer Growth by Dual Targeting of Cancer Cells and Bone Microenvironment in Mouse Models

Clinical cancer research, 2017-08, Vol.23 (15), p.4335-4346

2017

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Insights into immuno-oncology drug development landscape with focus on bone metastasis

Frontiers in immunology, 2023-07, Vol.14, p.1121878-1121878

2023

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Osteoimmuno-Oncology: Therapeutic Opportunities for Targeting Immune Cells in Bone Metastasis

Cells (Basel, Switzerland), 2021-06, Vol.10 (6), p.1529

2021

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Immunotherapies and Metastatic Cancers: Understanding Utility and Predictivity of Human Immune Cell Engrafted Mice in Preclinical Drug Development

Cancers, 2020-06, Vol.12 (6), p.1615

2020

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Secreted Tartrate-Resistant Acid Phosphatase 5b is a Marker of Osteoclast Number in Human Osteoclast Cultures and the Rat Ovariectomy Model

Calcified tissue international, 2008-02, Vol.82 (2), p.108-115

2008

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Survival Benefit With Radium-223 Dichloride in a Mouse Model of Breast Cancer Bone Metastasis

JNCI : Journal of the National Cancer Institute, 2013-06, Vol.105 (12), p.908-916

2013

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Biochemical Markers of Bone Metabolism and Prediction of Fracture in Elderly Women

Journal of bone and mineral research, 2004-03, Vol.19 (3), p.386-393

2004

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Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio

PloS one, 2017-08, Vol.12 (8), p.e0182904-e0182904

2017

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Clinical significance of serum BAP, TRACP 5b and ICTP as bone metabolic markers for bone metastasis screening in lung cancer patients

Clinica chimica acta, 2013-11, Vol.426, p.102-107

2013

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Abstract 364: Validation of human osteoclast cultures for studying the mode-of-action and identification of new compounds with the potential of inhibiting the vicious cycle in osteolytic bone metastases

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.364-364

2016

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Human Immune System Increases Breast Cancer-Induced Osteoblastic Bone Growth in a Humanized Mouse Model without Affecting Normal Bone

Journal of Immunology Research, 2019-01, Vol.2019, p.4260987-10

2019

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Tartrate-resistant acid phosphatase 5b (TRACP 5b) as a marker of bone resorption

Clinical laboratory (Heidelberg), 2006, Vol.52 (9-10), p.499

2006

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Intracellular Machinery for Matrix Degradation in Bone‐Resorbing Osteoclasts

Journal of bone and mineral research, 2004-09, Vol.19 (9), p.1432-1440

2004

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Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis

Molecular cancer research, 2012-05, Vol.10 (5), p.597-604

2012

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Abstract 381: PI3K inhibitor BAY 1082439 and radium-223 dichloride decrease tumor burden and tumor-induced bone formation in an established bone metastatic prostate cancer model in mice

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.381-381

2016

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Abstract 640: New models of breast and lung cancer bone metastases for preclinical efficacy testing

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.640-640

2016

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Increased osteoclast activity is associated with aggressiveness of osteosarcoma

International journal of oncology, 2008-12, Vol.33 (6), p.1231-1238

2008

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Dovitinib dilactic acid reduces tumor growth and tumor-induced bone changes in an experimental breast cancer bone growth model

Journal of bone oncology, 2019-06, Vol.16, p.100232-100232, Article 100232

2019

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Serum TRACP 5b Is a Useful Marker for Monitoring Alendronate Treatment: Comparison With Other Markers of Bone Turnover

Journal of bone and mineral research, 2005-10, Vol.20 (10), p.1804-1812

2005

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Tartrate-resistant acid phosphatase 5B is a specific and sensitive marker of bone resorption

Anticancer research, 2003-03, Vol.23 (2A), p.1027

Halleen, Jussi M

2003

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The cell biology of osteoclast function

Journal of cell science, 2000-02, Vol.113 ( Pt 3) (3), p.377-381

2000

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Novel and Conventional Preclinical Models to Investigate Bone Metastasis

Current molecular biology reports, 2019, Vol.5 (1), p.48-54

2019

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Properties and expression of human tartrate-resistant acid phosphatase isoform 5a by monocyte-derived cells

Journal of leukocyte biology, 2005-02, Vol.77 (2), p.209-218

2005

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Osteoclast-Derived Serum Tartrate-Resistant Acid Phosphatase 5b in Albers-Schonberg Disease (Type II Autosomal Dominant Osteopetrosis)

Clinical chemistry (Baltimore, Md.), 2004-05, Vol.50 (5), p.883-890

2004

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Tartrate‐Resistant Acid Phosphatase 5b: A Novel Serum Marker of Bone Resorption

Journal of bone and mineral research, 2000-07, Vol.15 (7), p.1337-1345

2000

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Radium-223 Inhibits Osseous Prostate Cancer Growth by Dual Targeting of Cancer Cells and Bone Microenvironment in Mouse Models

Insights into immuno-oncology drug development landscape with focus on bone metastasis

Osteoimmuno-Oncology: Therapeutic Opportunities for Targeting Immune Cells in Bone Metastasis

Immunotherapies and Metastatic Cancers: Understanding Utility and Predictivity of Human Immune Cell Engrafted Mice in Preclinical Drug Development

Secreted Tartrate-Resistant Acid Phosphatase 5b is a Marker of Osteoclast Number in Human Osteoclast Cultures and the Rat Ovariectomy Model

Survival Benefit With Radium-223 Dichloride in a Mouse Model of Breast Cancer Bone Metastasis

Biochemical Markers of Bone Metabolism and Prediction of Fracture in Elderly Women

Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio

Clinical significance of serum BAP, TRACP 5b and ICTP as bone metabolic markers for bone metastasis screening in lung cancer patients

Abstract 364: Validation of human osteoclast cultures for studying the mode-of-action and identification of new compounds with the potential of inhibiting the vicious cycle in osteolytic bone metastases

Human Immune System Increases Breast Cancer-Induced Osteoblastic Bone Growth in a Humanized Mouse Model without Affecting Normal Bone

Tartrate-resistant acid phosphatase 5b (TRACP 5b) as a marker of bone resorption

Intracellular Machinery for Matrix Degradation in Bone‐Resorbing Osteoclasts

Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis

Abstract 381: PI3K inhibitor BAY 1082439 and radium-223 dichloride decrease tumor burden and tumor-induced bone formation in an established bone metastatic prostate cancer model in mice

Abstract 640: New models of breast and lung cancer bone metastases for preclinical efficacy testing

Increased osteoclast activity is associated with aggressiveness of osteosarcoma

Dovitinib dilactic acid reduces tumor growth and tumor-induced bone changes in an experimental breast cancer bone growth model

Serum TRACP 5b Is a Useful Marker for Monitoring Alendronate Treatment: Comparison With Other Markers of Bone Turnover

Tartrate-resistant acid phosphatase 5B is a specific and sensitive marker of bone resorption

The cell biology of osteoclast function

Novel and Conventional Preclinical Models to Investigate Bone Metastasis

Properties and expression of human tartrate-resistant acid phosphatase isoform 5a by monocyte-derived cells

Osteoclast-Derived Serum Tartrate-Resistant Acid Phosphatase 5b in Albers-Schonberg Disease (Type II Autosomal Dominant Osteopetrosis)

Tartrate‐Resistant Acid Phosphatase 5b: A Novel Serum Marker of Bone Resorption

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