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Production of Site-Specific Antibody–Drug Conjugates Using Optimized Non-Natural Amino Acids in a Cell-Free Expression System

Bioconjugate chemistry, 2014-02, Vol.25 (2), p.351-361

2014

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Egg-Derived Anti-SARS-CoV-2 Immunoglobulin Y (IgY) With Broad Variant Activity as Intranasal Prophylaxis Against COVID-19

Frontiers in immunology, 2022-06, Vol.13, p.899617-899617

2022

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RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates

Scientific reports, 2017-06, Vol.7 (1), p.3026-13, Article 3026

2017

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Antibody Conjugates with Unnatural Amino Acids

Molecular pharmaceutics, 2015-06, Vol.12 (6), p.1848-1862

2015

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Engineering toward a bacterial "endoplasmic reticulum" for the rapid expression of immunoglobulin proteins

mAbs, 2014-05, Vol.6 (3), p.671-678

2014

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Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail

Viruses, 2018-05, Vol.10 (6), p.286

2018

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Cell-free technologies for biopharmaceutical research and production

Current opinion in biotechnology, 2022-08, Vol.76, p.102719-102719, Article 102719

2022

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Methods to Make Homogenous Antibody Drug Conjugates

Pharmaceutical research, 2015-11, Vol.32 (11), p.3480-3493

2015

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Melanocortins in the treatment of male and female sexual dysfunction

Current topics in medicinal chemistry, 2007-06, Vol.7 (11), p.1137

2007

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Development of an E. coli strain for cell‐free ADC manufacturing

Biotechnology and bioengineering, 2022-01, Vol.119 (1), p.162-175

2022

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Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial Cancers

Molecular cancer therapeutics, 2023-02, Vol.22 (2), p.155-167

2023

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A simplified and robust protocol for immunoglobulin expression in Escherichia coli cell-free protein synthesis systems

Biotechnology progress, 2015-05, Vol.31 (3), p.823-831

2015

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Site-Specific 89 Zr- and 111 In-Radiolabeling and In Vivo Evaluation of Glycan-free Antibodies by Azide-Alkyne Cycloaddition with a Non-natural Amino Acid

Bioconjugate chemistry, 2020-04, Vol.31 (4), p.1177-1187

2020

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Unnatural amino acids in novel antibody conjugates

Future medicinal chemistry, 2014-07, Vol.6 (11), p.1309-1324

2014

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Production of bispecific antibodies in "knobs-into-holes" using a cell-free expression system

mAbs, 2015-01, Vol.7 (1), p.231-242

2015

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RP-HPLC DAR Characterization of Site-Specific Antibody Drug Conjugates Produced in a Cell-Free Expression System

Organic process research & development, 2016-06, Vol.20 (6), p.1034-1043

2016

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A General Sequence Processing and Analysis Program for Protein Engineering

Journal of chemical information and modeling, 2014-10, Vol.54 (10), p.3020-3032

2014

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In vitro Fab display: a cell-free system for IgG discovery

Protein engineering, design and selection, 2014-04, Vol.27 (4), p.97-109

2014

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Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers?

Nature (London), 1987-02, Vol.325 (6107), p.811-813

1987

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Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells

Nature (London), 1988-09, Vol.335 (6185), p.40-45

1988

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In vitro and in vivo pharmacological profile of PL-3994, a novel cyclic peptide (Hept-cyclo(Cys-His-Phe- d -Ala-Gly-Arg- d -Nle-Asp-Arg-Ile-Ser-Cys)-Tyr-[Arg mimetic]-NH2 ) natriuretic peptide receptor-A agonist that is resistant to neutral endopeptidase and acts as a bronchodilator

Pulmonary pharmacology & therapeutics, 2013-04, Vol.26 (2), p.229-238

2013

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Site-Specific 89Zr- and 111In-Radiolabeling and In Vivo Evaluation of Glycan-free Antibodies by Azide–Alkyne Cycloaddition with a Non-natural Amino Acid

Bioconjugate chemistry, 2020-04, Vol.31 (4), p.1177-1187

2020

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Exogenous ATP raises cytoplasmic free calcium in fura-2 loaded piglet aortic endothelial cells

FEBS letters, 1986-10, Vol.207 (1), p.95-99

1986

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A simplified and robust protocol for immunoglobulin expression in E scherichia coli cell‐free protein synthesis systems

Biotechnology progress, 2015-05, Vol.31 (3), p.823-831

2015

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Inhibition of bovine nasal cartilage degradation by selective matrix metalloproteinase inhibitors

Biochemical journal, 1997-04, Vol.323 ( Pt 2) (2), p.483-488

1997

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Production of Site-Specific Antibody–Drug Conjugates Using Optimized Non-Natural Amino Acids in a Cell-Free Expression System

Egg-Derived Anti-SARS-CoV-2 Immunoglobulin Y (IgY) With Broad Variant Activity as Intranasal Prophylaxis Against COVID-19

RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates

Antibody Conjugates with Unnatural Amino Acids

Engineering toward a bacterial "endoplasmic reticulum" for the rapid expression of immunoglobulin proteins

Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail

Cell-free technologies for biopharmaceutical research and production

Methods to Make Homogenous Antibody Drug Conjugates

Melanocortins in the treatment of male and female sexual dysfunction

Development of an E. coli strain for cell‐free ADC manufacturing

Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial Cancers

A simplified and robust protocol for immunoglobulin expression in Escherichia coli cell-free protein synthesis systems

Site-Specific 89 Zr- and 111 In-Radiolabeling and In Vivo Evaluation of Glycan-free Antibodies by Azide-Alkyne Cycloaddition with a Non-natural Amino Acid

Unnatural amino acids in novel antibody conjugates

Production of bispecific antibodies in "knobs-into-holes" using a cell-free expression system

RP-HPLC DAR Characterization of Site-Specific Antibody Drug Conjugates Produced in a Cell-Free Expression System

A General Sequence Processing and Analysis Program for Protein Engineering

In vitro Fab display: a cell-free system for IgG discovery

Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers?

Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells

In vitro and in vivo pharmacological profile of PL-3994, a novel cyclic peptide (Hept-cyclo(Cys-His-Phe- d -Ala-Gly-Arg- d -Nle-Asp-Arg-Ile-Ser-Cys)-Tyr-[Arg mimetic]-NH2 ) natriuretic peptide receptor-A agonist that is resistant to neutral endopeptidase and acts as a bronchodilator

Site-Specific 89Zr- and 111In-Radiolabeling and In Vivo Evaluation of Glycan-free Antibodies by Azide–Alkyne Cycloaddition with a Non-natural Amino Acid

Exogenous ATP raises cytoplasmic free calcium in fura-2 loaded piglet aortic endothelial cells

A simplified and robust protocol for immunoglobulin expression in E scherichia coli cell‐free protein synthesis systems

Inhibition of bovine nasal cartilage degradation by selective matrix metalloproteinase inhibitors

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