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Physiologically based pharmacokinetic modeling in drug discovery and development: A pharmaceutical industry perspective

Clinical pharmacology and therapeutics, 2015-03, Vol.97 (3), p.247-262

2015

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The interaction between St John's wort and an oral contraceptive

Clinical pharmacology and therapeutics, 2003-12, Vol.74 (6), p.525-535

2003

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The effect of rifampin administration on the disposition of fexofenadine

Clinical pharmacology and therapeutics, 2001-03, Vol.69 (3), p.114-121

2001

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Activity of CYP2E1 and CYP3A enzymes in adults with moderate alcohol consumption : A comparison with nonalcoholics

Hepatology (Baltimore, Md.), 2005-05, Vol.41 (5), p.1144-1150

2005

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Inhibition of Human Intestinal Wall Metabolism by Macrolide Antibiotics: Effect of Clarithromycin on Cytochrome P450 3A4/5 Activity and Expression

Clinical pharmacology and therapeutics, 2005-03, Vol.77 (3), p.178-188

2005

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Dextromethorphan to dextrorphan urinary metabolic ratio does not reflect dextromethorphan oral clearance

Drug metabolism and disposition, 2005-07, Vol.33 (7), p.1052

2005

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The role of GABAergic modulation in motor function related neuronal network activity

NeuroImage (Orlando, Fla.), 2011-06, Vol.56 (3), p.1506-1510

2011

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Patients with elevated liver enzymes are not at higher risk for statin hepatotoxicity

Gastroenterology (New York, N.Y. 1943), 2004-05, Vol.126 (5), p.1287-1292

2004

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Understanding Disease-Drug Interactions in Cancer Patients: Implications for Dosing Within the Therapeutic Window

Clinical pharmacology and therapeutics, 2015-07, Vol.98 (1), p.76-86

2015

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Guidelines for the Management of Chronic Kidney Disease in HIV-Infected Patients: Recommendations of the HIV Medicine Association of the Infectious Diseases Society of America

Clinical infectious diseases, 2005-06, Vol.40 (11), p.1559-1585

2005

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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

Nature genetics, 2001-04, Vol.27 (4), p.383-391

2001

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Optimization of drug-drug interaction study design: comparison of minimal physiologically based pharmacokinetic models on prediction of CYP3A inhibition by ketoconazole

Drug metabolism and disposition, 2013-07, Vol.41 (7), p.1329

2013

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Mechanism-based inactivation of CYP3A by HIV protease inhibitors

The Journal of pharmacology and experimental therapeutics, 2005-02, Vol.312 (2), p.583

2005

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Prediction of cytochrome P450 3A inhibition by verapamil enantiomers and their metabolites

Drug metabolism and disposition, 2004-02, Vol.32 (2), p.259

2004

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Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis

Hepatology (Baltimore, Md.), 2003-03, Vol.37 (3), p.544-550

2003

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Exhaled Air and Aerosolized Droplet Dispersion During Application of a Jet Nebulizer

Chest, 2009-03, Vol.135 (3), p.648-654

2009

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The Effect of Echinacea ( Root) on Cytochrome P450 Activity in Vivo

Clinical pharmacology and therapeutics, 2004-01, Vol.75 (1), p.89-100

2004

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Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7

Drug metabolism and disposition, 2002-08, Vol.30 (8), p.883

2002

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The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity

Clinical pharmacology and therapeutics, 2003-09, Vol.74 (3), p.275-287

2003

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GLM-beamformer method demonstrates stationary field, alpha ERD and gamma ERS co-localisation with fMRI BOLD response in visual cortex

NeuroImage (Orlando, Fla.), 2005-05, Vol.26 (1), p.302-308

2005

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An in vitro model for predicting in vivo inhibition of cytochrome P450 3A4 by metabolic intermediate complex formation

Drug metabolism and disposition, 2000-09, Vol.28 (9), p.1031

2000

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The missing link: analogous human and primate cortical gamma oscillations

NeuroImage (Orlando, Fla.), 2005-05, Vol.26 (1), p.13-17

2005

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Diabetes mellitus increases the in vivo activity of cytochrome P450 2E1 in humans

British journal of clinical pharmacology, 2003-01, Vol.55 (1), p.77-85

2003

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Effect of St John's wort on the pharmacokinetics of fexofenadine

Clinical pharmacology and therapeutics, 2002-06, Vol.71 (6), p.414-420

2002

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Differential mechanism-based inhibition of CYP3A4 and CYP3A5 by verapamil

Drug metabolism and disposition, 2005-05, Vol.33 (5), p.664

2005

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Physiologically based pharmacokinetic modeling in drug discovery and development: A pharmaceutical industry perspective

The interaction between St John's wort and an oral contraceptive

The effect of rifampin administration on the disposition of fexofenadine

Activity of CYP2E1 and CYP3A enzymes in adults with moderate alcohol consumption : A comparison with nonalcoholics

Inhibition of Human Intestinal Wall Metabolism by Macrolide Antibiotics: Effect of Clarithromycin on Cytochrome P450 3A4/5 Activity and Expression

Dextromethorphan to dextrorphan urinary metabolic ratio does not reflect dextromethorphan oral clearance

The role of GABAergic modulation in motor function related neuronal network activity

Patients with elevated liver enzymes are not at higher risk for statin hepatotoxicity

Understanding Disease-Drug Interactions in Cancer Patients: Implications for Dosing Within the Therapeutic Window

Guidelines for the Management of Chronic Kidney Disease in HIV-Infected Patients: Recommendations of the HIV Medicine Association of the Infectious Diseases Society of America

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

Optimization of drug-drug interaction study design: comparison of minimal physiologically based pharmacokinetic models on prediction of CYP3A inhibition by ketoconazole

Mechanism-based inactivation of CYP3A by HIV protease inhibitors

Prediction of cytochrome P450 3A inhibition by verapamil enantiomers and their metabolites

Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis

Exhaled Air and Aerosolized Droplet Dispersion During Application of a Jet Nebulizer

The Effect of Echinacea ( Root) on Cytochrome P450 Activity in Vivo

Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7

The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity

GLM-beamformer method demonstrates stationary field, alpha ERD and gamma ERS co-localisation with fMRI BOLD response in visual cortex

An in vitro model for predicting in vivo inhibition of cytochrome P450 3A4 by metabolic intermediate complex formation

The missing link: analogous human and primate cortical gamma oscillations

Diabetes mellitus increases the in vivo activity of cytochrome P450 2E1 in humans

Effect of St John's wort on the pharmacokinetics of fexofenadine

Differential mechanism-based inhibition of CYP3A4 and CYP3A5 by verapamil

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