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In-vitro anti-inflammatory and immunomodulatory effects of grepafloxacin in zymogen A- or Staphylococcus aureus-stimulated human THP-1 monocytes

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2003-06, Vol.9 (2), p.134-143

2003

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Synthesis and Cytotoxicity of Substituted Ethyl 2-Phenacyl-3-phenylpyrrole-4-carboxylates

Archiv der Pharmazie (Weinheim), 2003-06, Vol.336 (3), p.181-190

2003

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Human THP-1 monocyte uptake and cellular disposition of 14C-grepafloxacin

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2004-02, Vol.10 (1), p.11-18

2004

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Targeting of Human Tmolt4 Leukemic Type II IMP Dehydrogenase by Cyclic Imide Related Derivatives

Archiv der Pharmazie (Weinheim), 2001-07, Vol.334 (7), p.229-234

2001

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Effects of moxifloxacin in zymogen A or S. aureus stimulated human THP-1 monocytes on the inflammatory process and the spread of infection

Life sciences (1973), 2003-10, Vol.73 (21), p.2675-2685

2003

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Disposition and intracellular levels of moxifloxacin in human THP-1 monocytes in unstimulated and stimulated conditions

International journal of antimicrobial agents, 2003-12, Vol.22 (6), p.579-587

2003

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Cytotoxicity and mode of action of vanada- and niobatricarbadecaboranyl monohalide complexes in human HL-60 promyelocytic leukemia cells

Journal of inorganic biochemistry, 2003-01, Vol.93 (3), p.125-131

2003

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Antitumor activity of mono- and dimetallic transition metal carborane complexes of Ta, Fe, Co, Mo, or W

Anticancer research, 2000-07, Vol.20 (4), p.2345

2000

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Selective Inhibition of Human Molt-4 Leukemia Type II Inosine 5‘-Monophosphate Dehydrogenase by the 1,5-Diazabicyclo[3.1.0]hexane-2,4-diones

Biochemistry (Easton), 2000-11, Vol.39 (45), p.13641-13650

2000

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Disposition and intracellular activity of azithromycin in human THP-1 acute monocytes

International journal of antimicrobial agents, 2002-11, Vol.20 (5), p.348-360

2002

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Implications of selective type II IMP dehydrogenase (IMPDH) inhibition by the 6-ethoxycarbonyl-3,3-disubstituted-1,5-diazabicyclo[3.1.0]hexane-2,4-diones on tumor cell death

Biochemical pharmacology, 2001-07, Vol.62 (1), p.91-100

2001

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Effects of alatrofloxacin, the parental prodrug of trovafloxacin, on phagocytic, anti-inflammatory and immunomodulation events of human THP-1 monocytes

Biomedicine & pharmacotherapy, 2003-10, Vol.57 (8), p.359-365

2003

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Mechanism of action of the antitumor agents 6‐benzoyl‐3,3‐disubstituted‐1,5‐diazabicyclo[3.1.0]hexane‐2,4‐diones: Potent inhibitors of human type II inosine 5′‐monophosphate dehydrogenase

International journal of cancer, 2001-10, Vol.94 (2), p.275-281

2001

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Synthesis and antitumor activity of a series of sulfone analogs of 1,4-naphthoquinone

Journal of medicinal chemistry, 1981-07, Vol.24 (7), p.853-858

1981

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Hypolipidemic activity of phthalimide derivatives. 7. Structure-activity studies of indazolone analogs

Journal of medicinal chemistry, 1984-06, Vol.27 (6), p.768-772

1984

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Antitumor agents. 21. A proposed mechanism for inhibition of cancer growth by tenulin and helenalin and related cyclopentenones

Journal of medicinal chemistry, 1977-03, Vol.20 (3), p.333-337

1977

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Hypolipidemic activity of phthalimide derivatives. 3. A comparison of phthalimide and 1,2-benzisothiazolin-3-one 1,1-dioxide derivatives to phthalimidine and 1,2-benzisothiazoline 1,1-dioxide congeners

Journal of medicinal chemistry, 1983-02, Vol.26 (2), p.243-246

1983

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Antitumor agents. 33. Isolation and structural elucidation of bruceoside -A and -B, novel antileukemic quassinoid glycosides, and brucein -D and -E from Brucea javanica

Journal of organic chemistry, 1979-06, Vol.44 (13), p.2180-2185

1979

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Hypolipidemic activity of phthalimide derivatives. 2. N-Phenylphthalimide and derivatives

Journal of medicinal chemistry, 1983-02, Vol.26 (2), p.237-243

1983

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The cytotoxicity of copper(II) complexes of heterocyclic thiosemicarbazones and 2-substituted pyridine N-oxides

Anti-cancer drugs, 1993-04, Vol.4 (2), p.241-250

1993

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Boron analogs of the .alpha.-amino acids. Synthesis, x-ray crystal structure, and biological activity of ammonia-carboxyborane, the boron analog of glycine

Journal of the American Chemical Society, 1980-09, Vol.102 (20), p.6343-6344

1980

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Synthesis and Cytotoxicity of 2,4-Disubstituted and 2,3,4-Trisubstituted Brominated Pyrroles in Murine and Human Cultured Tumor Cells

Archiv der Pharmazie (Weinheim), 2000-01, Vol.333 (1), p.3-9

2000

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Hypolipidemic activity of phthalimide derivatives. 1. N-Substituted phthalimide derivatives

Journal of medicinal chemistry, 1979-11, Vol.22 (11), p.1399-1402

1979

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Hypolipidemic, Anti-Inflammatory, and Antineoplastic Activity and Cytotoxicity of Flavonolignans Isolated from Hydnocarpus wightiana Seeds

Journal of natural products (Washington, D.C.), 1991-09, Vol.54 (5), p.1298-1302

1991

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Tmolt4 Leukemic Type II Isoform of IMP Dehydrogenase as a Target for 1,2,4-Triazolidine-3,5-diones, 1-(1-(3-Methylphenyl)ethylidineamino)-4,4-diethyl-3,5-azetidinediones, 3,5-Isoxazolidinediones, and 4,4-Disubstituted-3,5-pyrazolidinediones

Archiv der Pharmazie (Weinheim), 2001-04, Vol.334 (4), p.109-116

2001

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In-vitro anti-inflammatory and immunomodulatory effects of grepafloxacin in zymogen A- or Staphylococcus aureus-stimulated human THP-1 monocytes

Synthesis and Cytotoxicity of Substituted Ethyl 2-Phenacyl-3-phenylpyrrole-4-carboxylates

Human THP-1 monocyte uptake and cellular disposition of 14C-grepafloxacin

Targeting of Human Tmolt4 Leukemic Type II IMP Dehydrogenase by Cyclic Imide Related Derivatives

Effects of moxifloxacin in zymogen A or S. aureus stimulated human THP-1 monocytes on the inflammatory process and the spread of infection

Disposition and intracellular levels of moxifloxacin in human THP-1 monocytes in unstimulated and stimulated conditions

Cytotoxicity and mode of action of vanada- and niobatricarbadecaboranyl monohalide complexes in human HL-60 promyelocytic leukemia cells

Antitumor activity of mono- and dimetallic transition metal carborane complexes of Ta, Fe, Co, Mo, or W

Selective Inhibition of Human Molt-4 Leukemia Type II Inosine 5‘-Monophosphate Dehydrogenase by the 1,5-Diazabicyclo[3.1.0]hexane-2,4-diones

Disposition and intracellular activity of azithromycin in human THP-1 acute monocytes

Implications of selective type II IMP dehydrogenase (IMPDH) inhibition by the 6-ethoxycarbonyl-3,3-disubstituted-1,5-diazabicyclo[3.1.0]hexane-2,4-diones on tumor cell death

Effects of alatrofloxacin, the parental prodrug of trovafloxacin, on phagocytic, anti-inflammatory and immunomodulation events of human THP-1 monocytes

Mechanism of action of the antitumor agents 6‐benzoyl‐3,3‐disubstituted‐1,5‐diazabicyclo[3.1.0]hexane‐2,4‐diones: Potent inhibitors of human type II inosine 5′‐monophosphate dehydrogenase

Synthesis and antitumor activity of a series of sulfone analogs of 1,4-naphthoquinone

Hypolipidemic activity of phthalimide derivatives. 7. Structure-activity studies of indazolone analogs

Antitumor agents. 21. A proposed mechanism for inhibition of cancer growth by tenulin and helenalin and related cyclopentenones

Hypolipidemic activity of phthalimide derivatives. 3. A comparison of phthalimide and 1,2-benzisothiazolin-3-one 1,1-dioxide derivatives to phthalimidine and 1,2-benzisothiazoline 1,1-dioxide congeners

Antitumor agents. 33. Isolation and structural elucidation of bruceoside -A and -B, novel antileukemic quassinoid glycosides, and brucein -D and -E from Brucea javanica

Hypolipidemic activity of phthalimide derivatives. 2. N-Phenylphthalimide and derivatives

The cytotoxicity of copper(II) complexes of heterocyclic thiosemicarbazones and 2-substituted pyridine N-oxides

Boron analogs of the .alpha.-amino acids. Synthesis, x-ray crystal structure, and biological activity of ammonia-carboxyborane, the boron analog of glycine

Synthesis and Cytotoxicity of 2,4-Disubstituted and 2,3,4-Trisubstituted Brominated Pyrroles in Murine and Human Cultured Tumor Cells

Hypolipidemic activity of phthalimide derivatives. 1. N-Substituted phthalimide derivatives

Hypolipidemic, Anti-Inflammatory, and Antineoplastic Activity and Cytotoxicity of Flavonolignans Isolated from Hydnocarpus wightiana Seeds

Tmolt4 Leukemic Type II Isoform of IMP Dehydrogenase as a Target for 1,2,4-Triazolidine-3,5-diones, 1-(1-(3-Methylphenyl)ethylidineamino)-4,4-diethyl-3,5-azetidinediones, 3,5-Isoxazolidinediones, and 4,4-Disubstituted-3,5-pyrazolidinediones

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