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The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

Nature reviews. Drug discovery, 2014-01, Vol.13 (1), p.63-79

2014

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Transduction of mechanical and cytoskeletal cues by YAP and TAZ

Nature reviews. Molecular cell biology, 2012-09, Vol.13 (9), p.591-600

2012

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Hippo signaling: growth control and beyond

Development (Cambridge), 2011-01, Vol.138 (1), p.9-22

2011

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The Hippo pathway effector YAP controls mouse hepatic stellate cell activation

Journal of hepatology, 2015-09, Vol.63 (3), p.679-688

2015

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Discovery of transcription factors and regulatory regions driving in vivo tumor development by ATAC-seq and FAIRE-seq open chromatin profiling

PLoS genetics, 2015-02, Vol.11 (2), p.e1004994

2015

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Modulating F-actin organization induces organ growth by affecting the Hippo pathway

The EMBO journal, 2011-06, Vol.30 (12), p.2325-2335

2011

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Initiation of hepatic stellate cell activation extends into chronic liver disease

Cell death & disease, 2021-11, Vol.12 (12), p.1110-1110, Article 1110

2021

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Regulation of the Hippo pathway by cell architecture and mechanical signals

Seminars in cell & developmental biology, 2012-09, Vol.23 (7), p.803-811

2012

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MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway

Nature communications, 2015-10, Vol.6 (1), p.8357, Article 8357

2015

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Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice

Science (American Association for the Advancement of Science), 2019-11, Vol.366 (6468), p.1029-1034

2019

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Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (4), p.1437-1442

2010

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Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

Nature communications, 2015-04, Vol.6 (1), p.6683-6683, Article 6683

2015

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An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model

Current biology, 2016-08, Vol.26 (16), p.2101-2113

2016

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apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila

Proceedings of the National Academy of Sciences - PNAS, 2010-09, Vol.107 (36), p.15810-15815

2010

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Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer

Nature communications, 2024-03, Vol.15 (1), p.2700-2700, Article 2700

2024

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Genes & development, 2007-11, Vol.21 (21), p.2747-2761

2007

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Tumor suppression by cell competition through regulation of the Hippo pathway

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (2), p.484-489

2012

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Differential regulation of the Hippo pathway by adherens junctions and apical–basal cell polarity modules

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (6), p.1785-1790

2015

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Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis

Gastroenterology (New York, N.Y. 1943), 2021-02, Vol.160 (3), p.847-862

2021

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The bantam MicroRNA Is a Target of the Hippo Tumor-Suppressor Pathway

Current biology, 2006-10, Vol.16 (19), p.1895-1904

2006

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Diversification of complex butterfly wing patterns by repeated regulatory evolution of a Wnt ligand

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (31), p.12632-12637

2012

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A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models

Molecular cancer therapeutics, 2024-01, Vol.23 (1), p.3-13

2024

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Shared enhancer gene regulatory networks between wound and oncogenic programs

eLife, 2023-05, Vol.12

2023

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YAP and TAZ Heterogeneity in Primary Liver Cancer: An Analysis of Its Prognostic and Diagnostic Role

International journal of molecular sciences, 2019-02, Vol.20 (3), p.638

2019

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The Fat Cadherin Acts through the Hippo Tumor-Suppressor Pathway to Regulate Tissue Size

Current biology, 2006-11, Vol.16 (21), p.2090-2100

2006

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The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

Transduction of mechanical and cytoskeletal cues by YAP and TAZ

Hippo signaling: growth control and beyond

The Hippo pathway effector YAP controls mouse hepatic stellate cell activation

Discovery of transcription factors and regulatory regions driving in vivo tumor development by ATAC-seq and FAIRE-seq open chromatin profiling

Modulating F-actin organization induces organ growth by affecting the Hippo pathway

Initiation of hepatic stellate cell activation extends into chronic liver disease

Regulation of the Hippo pathway by cell architecture and mechanical signals

MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway

Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model

apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila

Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Tumor suppression by cell competition through regulation of the Hippo pathway

Differential regulation of the Hippo pathway by adherens junctions and apical–basal cell polarity modules

Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis

The bantam MicroRNA Is a Target of the Hippo Tumor-Suppressor Pathway

Diversification of complex butterfly wing patterns by repeated regulatory evolution of a Wnt ligand

A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models

Shared enhancer gene regulatory networks between wound and oncogenic programs

YAP and TAZ Heterogeneity in Primary Liver Cancer: An Analysis of Its Prognostic and Diagnostic Role

The Fat Cadherin Acts through the Hippo Tumor-Suppressor Pathway to Regulate Tissue Size

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