UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Kinase-targeted libraries: The design and synthesis of novel, potent, and selective kinase inhibitors

Drug discovery today, 2009-03, Vol.14 (5), p.291-297

2009

Volltextzugriff (PDF)

Druggability Indices for Protein Targets Derived from NMR-Based Screening Data

Journal of medicinal chemistry, 2005-04, Vol.48 (7), p.2518-2525

2005

Volltextzugriff (PDF)

Rational approaches to targeted polypharmacology: creating and navigating protein–ligand interaction networks

Current opinion in chemical biology, 2010-08, Vol.14 (4), p.498-504

2010

Volltextzugriff (PDF)

A decade of fragment-based drug design: strategic advances and lessons learned

Nature reviews. Drug discovery, 2007-03, Vol.5 (3), p.211-219

2007

Volltextzugriff (PDF)

Cheminformatic Tools for Medicinal Chemists

Journal of medicinal chemistry, 2010-07, Vol.53 (13), p.4830-4841

2010

Volltextzugriff (PDF)

ALARM NMR: A Rapid and Robust Experimental Method To Detect Reactive False Positives in Biochemical Screens

Journal of the American Chemical Society, 2005-01, Vol.127 (1), p.217-224

2005

Volltextzugriff (PDF)

Fragment-Based Drug Design: How Big Is Too Big?

Journal of medicinal chemistry, 2006-11, Vol.49 (24), p.6972-6976

HAJDUK, Philip J

2006

Volltextzugriff (PDF)

Discovering High-Affinity Ligands for Proteins: SAR by NMR

Science (American Association for the Advancement of Science), 1996-11, Vol.274 (5292), p.1531-1534

1996

Volltextzugriff (PDF)

Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (19), p.7875-7880

2007

Volltextzugriff (PDF)

Molecular Determinants of Species-Specific Activation or Blockade of TRPA1 Channels

The Journal of neuroscience, 2008-05, Vol.28 (19), p.5063-5071

2008

Volltextzugriff (PDF)

Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked-Fragment Strategy

Journal of the American Chemical Society, 2003-04, Vol.125 (14), p.4087-4096

2003

Volltextzugriff (PDF)

Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR

Bioorganic & medicinal chemistry letters, 2010-11, Vol.20 (22), p.6587-6591

2010

Volltextzugriff (PDF)

Navigating the kinome

Nature chemical biology, 2011-04, Vol.7 (4), p.200-202

2011

Volltextzugriff (PDF)

Fragment Screening and Assembly: A Highly Efficient Approach to a Selective and Cell Active Protein Tyrosine Phosphatase 1B Inhibitor

Journal of medicinal chemistry, 2003-09, Vol.46 (20), p.4232-4235

2003

Volltextzugriff (PDF)

Predicting protein druggability

Drug discovery today, 2005-12, Vol.10 (23-24), p.1675-1682

2005

Volltextzugriff (PDF)

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

Nature (London), 1994-09, Vol.371 (6493), p.168-170

1994

Volltextzugriff (PDF)

High-Throughput Nuclear Magnetic Resonance-Based Screening

Journal of medicinal chemistry, 1999-07, Vol.42 (13), p.2315-2317

1999

Volltextzugriff (PDF)

Effects of Conformational Dynamics on Predicted Protein Druggability

ChemMedChem, 2006-01, Vol.1 (1), p.70-72

2006

Volltextzugriff (PDF)

Structural Characterization of a Soluble Amyloid β-Peptide Oligomer

Biochemistry (Easton), 2009-03, Vol.48 (9), p.1870-1877

2009

Volltextzugriff (PDF)

Discovery of a novel small molecule binding site of human survivin

Bioorganic & medicinal chemistry letters, 2007-06, Vol.17 (11), p.3122-3129

2007

Volltextzugriff (PDF)

SOS-NMR: A Saturation Transfer NMR-Based Method for Determining the Structures of Protein−Ligand Complexes

Journal of the American Chemical Society, 2004-03, Vol.126 (8), p.2390-2398

2004

Volltextzugriff (PDF)

SAR by NMR: Putting the Pieces Together

Molecular interventions, 2006-10, Vol.6 (5), p.266-272

Hajduk, Philip J

2006

Volltextzugriff (PDF)

Healthy skepticism: assessing realistic model performance

Drug discovery today, 2009-04, Vol.14 (7), p.420-427

2009

Volltextzugriff (PDF)

Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design

Journal of medicinal chemistry, 2021-01, Vol.64 (1), p.417-429

2021

Volltextzugriff (PDF)

1 – 25 von 103

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(96)
Mit Volltextzugriff
(96)

Publikationsform

Artikel
(102)
Buchkapitel
(1)

Sprache

Englisch
(103)
Japanisch
(1)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Kinase-targeted libraries: The design and synthesis of novel, potent, and selective kinase inhibitors

Druggability Indices for Protein Targets Derived from NMR-Based Screening Data

Rational approaches to targeted polypharmacology: creating and navigating protein–ligand interaction networks

A decade of fragment-based drug design: strategic advances and lessons learned

Cheminformatic Tools for Medicinal Chemists

ALARM NMR: A Rapid and Robust Experimental Method To Detect Reactive False Positives in Biochemical Screens

Fragment-Based Drug Design: How Big Is Too Big?

Discovering High-Affinity Ligands for Proteins: SAR by NMR

Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS

Molecular Determinants of Species-Specific Activation or Blockade of TRPA1 Channels

Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked-Fragment Strategy

Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR

Navigating the kinome

Fragment Screening and Assembly: A Highly Efficient Approach to a Selective and Cell Active Protein Tyrosine Phosphatase 1B Inhibitor

Predicting protein druggability

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

High-Throughput Nuclear Magnetic Resonance-Based Screening

Effects of Conformational Dynamics on Predicted Protein Druggability

Structural Characterization of a Soluble Amyloid β-Peptide Oligomer

Discovery of a novel small molecule binding site of human survivin

SOS-NMR: A Saturation Transfer NMR-Based Method for Determining the Structures of Protein−Ligand Complexes

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

SAR by NMR: Putting the Pieces Together

Healthy skepticism: assessing realistic model performance

Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design

Suchergebnisse filtern