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Gene Doping

International journal of sports medicine, 2006-04, Vol.27 (4), p.257-266

2006

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Targeted adenovirus mediated inhibition of NF-κB-dependent inflammatory gene expression in endothelial cells in vitro and in vivo

Journal of controlled release, 2013-02, Vol.166 (1), p.57-65

2013

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Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors

Gene therapy, 2003-11, Vol.10 (23), p.1982-1991

2003

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Evaluation of tumor-specific promoter activities in melanoma

Gene therapy, 2005-02, Vol.12 (4), p.330-338

2005

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Tumor-specific gene transfer via an adenoviral vector targeted to the pan-carcinoma antigen EpCAM

Gene therapy, 1999-08, Vol.6 (8), p.1469-1474

1999

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Combined Targeting of Adenoviruses to Integrins and Epidermal Growth Factor Receptors Increases Gene Transfer into Primary Glioma Cells and Spheroids

Clinical cancer research, 2001-03, Vol.7 (3), p.641-650

2001

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Targeted cancer gene therapy: the flexibility of adenoviral gene therapy vectors

Journal of controlled release, 2003-02, Vol.87 (1), p.159-165

2003

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A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer

British journal of cancer, 2001-02, Vol.84 (4), p.550-557

2001

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Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX‐GA3 in combination with a monoclonal antibody β‐glucuronidase conjugate

International journal of cancer, 2001-02, Vol.91 (4), p.550-554

2001

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Recombinant adenovirus vectors with knobless fibers for targeted gene transfer

Gene therapy, 2000-11, Vol.7 (22), p.1940-1946

2000

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Highly efficient and carcinoma-specific adenoviral replication restricted by the EGP-2 promoter

Journal of controlled release, 2007-01, Vol.117 (1), p.1-10

2007

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Effective single chain antibody (scFv) concentrations in vivo via adenoviral vector mediated expression of secretory scFv

Gene therapy, 2002-02, Vol.9 (4), p.256-262

2002

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Secreted and tumour targeted human carboxylesterase for activation of irinotecan

British journal of cancer, 2002-09, Vol.87 (6), p.659-664

2002

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Epidermal growth factor receptor targeting of replication competent adenovirus enhances cytotoxicity in bladder cancer

The Journal of urology, 2002-07, Vol.168 (1), p.266

2002

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Protein transduction domains and their utility in gene therapy

Current gene therapy, 2003-10, Vol.3 (5), p.486

2003

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A fully human anti-Ep-CAM scFv-beta-glucuronidase fusion protein for selective chemotherapy with a glucuronide prodrug

British journal of cancer, 2002-03, Vol.86 (5), p.811-818

2002

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Secretion of thymidine kinase to increase the effectivity of suicide gene therapy results in the loss of enzymatic activity

Journal of drug targeting, 2008, Vol.16 (1), p.26-35

2008

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Employment of liver tissue slice analysis to assay hepatotoxicity linked to replicative and nonreplicative adenoviral agents

Cancer gene therapy, 2006-06, Vol.13 (6), p.606-618

2006

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Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11

British journal of cancer, 2005-03, Vol.92 (5), p.882-887

2005

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The carcinoma-specific epithelial glycoprotein-2 promoter controls efficient and selective gene expression in an adenoviral context

Cancer gene therapy, 2006-02, Vol.13 (2), p.150-158

2006

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Prostate specific membrane antigen (PSMA) is a tissue-specific target for adenoviral transduction of prostate cancer in vitro

The Prostate, 2005-02, Vol.62 (3), p.253-259

2005

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An ex vivo human model system to evaluate specificity of replicating and non-replicating gene therapy agents

The journal of gene medicine, 2006-01, Vol.8 (1), p.35-41

2006

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Beta-glucuronidase-mediated drug release

Current pharmaceutical design, 2002-01, Vol.8 (15), p.1391

2002

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Novel anthracycline-spacer-β-glucuronide, -β-glucoside, and -β-galactoside prodrugs for application in selective chemotherapy

Bioorganic & medicinal chemistry, 1999-08, Vol.7 (8), p.1597-1610

1999

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Zirconium-Labeled Monoclonal Antibodies and Their Distribution in Tumor-Bearing Nude Mice

The Journal of nuclear medicine (1978), 1997-01, Vol.38 (1), p.112-118

1997

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Gene Doping

Targeted adenovirus mediated inhibition of NF-κB-dependent inflammatory gene expression in endothelial cells in vitro and in vivo

Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors

Evaluation of tumor-specific promoter activities in melanoma

Tumor-specific gene transfer via an adenoviral vector targeted to the pan-carcinoma antigen EpCAM

Combined Targeting of Adenoviruses to Integrins and Epidermal Growth Factor Receptors Increases Gene Transfer into Primary Glioma Cells and Spheroids

Targeted cancer gene therapy: the flexibility of adenoviral gene therapy vectors

A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer

Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX‐GA3 in combination with a monoclonal antibody β‐glucuronidase conjugate

Recombinant adenovirus vectors with knobless fibers for targeted gene transfer

Highly efficient and carcinoma-specific adenoviral replication restricted by the EGP-2 promoter

Effective single chain antibody (scFv) concentrations in vivo via adenoviral vector mediated expression of secretory scFv

Secreted and tumour targeted human carboxylesterase for activation of irinotecan

Epidermal growth factor receptor targeting of replication competent adenovirus enhances cytotoxicity in bladder cancer

Protein transduction domains and their utility in gene therapy

A fully human anti-Ep-CAM scFv-beta-glucuronidase fusion protein for selective chemotherapy with a glucuronide prodrug

Secretion of thymidine kinase to increase the effectivity of suicide gene therapy results in the loss of enzymatic activity

Employment of liver tissue slice analysis to assay hepatotoxicity linked to replicative and nonreplicative adenoviral agents

Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11

The carcinoma-specific epithelial glycoprotein-2 promoter controls efficient and selective gene expression in an adenoviral context

Prostate specific membrane antigen (PSMA) is a tissue-specific target for adenoviral transduction of prostate cancer in vitro

An ex vivo human model system to evaluate specificity of replicating and non-replicating gene therapy agents

Beta-glucuronidase-mediated drug release

Novel anthracycline-spacer-β-glucuronide, -β-glucoside, and -β-galactoside prodrugs for application in selective chemotherapy

Zirconium-Labeled Monoclonal Antibodies and Their Distribution in Tumor-Bearing Nude Mice

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