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Substituted Imidazoles as Glucagon Receptor Antagonists

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (18), p.2549-2553

2001

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Potent, orally absorbed glucagon receptor antagonists

Bioorganic & medicinal chemistry letters, 1999-03, Vol.9 (5), p.641-646

1999

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Interdependence of Gemcitabine Treatment, Transporter Expression, and Resistance in Human Pancreatic Carcinoma Cells

Neoplasia (New York, N.Y.), 2010-09, Vol.12 (9), p.740-747

2010

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1039 POSTER Epigenetic Alterations in Lung Cancer Susceptibility Regions

European journal of cancer (1990), 2011, Vol.47, p.S107-S107

2011

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Stromelysin‐1: Three‐dimensional structure of the inhibited catalytic domain and of the C‐truncated proenzyme

Protein science, 1995-10, Vol.4 (10), p.1966-1976

1995

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Desmoplasia and chemoresistance in pancreatic cancer

Cancers, 2014-10, Vol.6 (4), p.2137-2154

2014

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The discovery and potential of N-sulfonylated dipeptide VLA-4 antagonists

Current topics in medicinal chemistry, 2004-01, Vol.4 (14), p.1461

Hagmann, William K

2004

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Importance of mechanistic drug metabolism studies in support of drug discovery: A case study with an N -sulfonylated dipeptide VLA-4 antagonist in rats

Xenobiotica, 2008-02, Vol.38 (2), p.223-237

2008

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Cell proliferation status, cytokine action and protein tyrosine phosphorylation modulate leukotriene biosynthesis in a basophil leukaemia and a mastocytoma cell line

Biochemical journal, 1994-04, Vol.299 (2), p.467-472

HAGMANN, W

1994

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Substituted 2-aminopyridines as inhibitors of nitric oxide synthases

Bioorganic & medicinal chemistry letters, 2000-09, Vol.10 (17), p.1975-1978

2000

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Characterization of a Novel, Non-peptidyl Antagonist of the Human Glucagon Receptor

The Journal of biological chemistry, 1999-03, Vol.274 (13), p.8694-8697

1999

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Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis

Journal of hepatology, 2003-11, Vol.39 (5), p.693-702

2003

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Orally active .beta.-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones

Journal of medicinal chemistry, 1992-10, Vol.35 (21), p.3745-3754

1992

Volltextzugriff (PDF)

The NMR structure of the inhibited catalytic domain of human stromelysin-1

Nature structural & molecular biology, 1994-02, Vol.1 (2), p.111-118

1994

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Deprotection of N- tert-butoxycarbonyl (Boc) groups in the presence of tert-butyl esters

Tetrahedron letters, 2000-09, Vol.41 (36), p.7013-7016

2000

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Human fibroblast stromelysin catalytic domain: expression, purification, and characterization of a C-terminally truncated form

Biochemistry (Easton), 1991-07, Vol.30 (26), p.6476-6483

1991

Volltextzugriff (PDF)

Characterization of zinc-binding sites in human stromelysin-1: stoichiometry of the catalytic domain and identification of a cysteine ligand in the proenzyme

Biochemistry (Easton), 1992-05, Vol.31 (19), p.4535-4540

1992

Volltextzugriff (PDF)

A spread spectrum communication system for load management and distribution automation

IEEE transactions on power delivery, 1989-01, Vol.4 (1), p.75-81

Hagmann, W.

1989

Volltextzugriff (PDF)

Leukotrienes as Mediators in Tissue Trauma

Science (American Association for the Advancement of Science), 1985-10, Vol.230 (4723), p.330-332

1985

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Secondary structure and zinc ligation of human recombinant short-form stromelysin by multidimensional heteronuclear NMR

Biochemistry (Easton), 1993-12, Vol.32 (48), p.13098-13108

1993

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Network synchronization

Proceedings of the IEEE, 1985-01, Vol.73 (10), p.1445-1467

1985

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Evidence linking CD44‐positive cells and gemcitabine resistance in pancreatic cancer cells: need for further substantiation

International journal of cancer, 2010-07, Vol.127 (1), p.246-247

2010

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Mechanism of inhibition of human leukocyte elastase by two cephalosporin derivatives

Biochemistry (Easton), 1992-06, Vol.31 (21), p.4980-4986

1992

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Substituted 4,6-diaminoquinolines as inhibitors of C5a receptor binding

Journal of medicinal chemistry, 1992-01, Vol.35 (2), p.252-258

1992

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Leukotrienes as mediators in frog virus 3-induced hepatitis in rats

Hepatology (Baltimore, Md.), 1987-07, Vol.7 (4), p.732-736

1987

Volltextzugriff (PDF)

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Substituted Imidazoles as Glucagon Receptor Antagonists

Potent, orally absorbed glucagon receptor antagonists

Interdependence of Gemcitabine Treatment, Transporter Expression, and Resistance in Human Pancreatic Carcinoma Cells

1039 POSTER Epigenetic Alterations in Lung Cancer Susceptibility Regions

Stromelysin‐1: Three‐dimensional structure of the inhibited catalytic domain and of the C‐truncated proenzyme

Desmoplasia and chemoresistance in pancreatic cancer

The discovery and potential of N-sulfonylated dipeptide VLA-4 antagonists

Importance of mechanistic drug metabolism studies in support of drug discovery: A case study with an N -sulfonylated dipeptide VLA-4 antagonist in rats

Cell proliferation status, cytokine action and protein tyrosine phosphorylation modulate leukotriene biosynthesis in a basophil leukaemia and a mastocytoma cell line

Substituted 2-aminopyridines as inhibitors of nitric oxide synthases

Characterization of a Novel, Non-peptidyl Antagonist of the Human Glucagon Receptor

Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis

Orally active .beta.-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones

The NMR structure of the inhibited catalytic domain of human stromelysin-1

Deprotection of N- tert-butoxycarbonyl (Boc) groups in the presence of tert-butyl esters

Human fibroblast stromelysin catalytic domain: expression, purification, and characterization of a C-terminally truncated form

Characterization of zinc-binding sites in human stromelysin-1: stoichiometry of the catalytic domain and identification of a cysteine ligand in the proenzyme

A spread spectrum communication system for load management and distribution automation

Leukotrienes as Mediators in Tissue Trauma

Secondary structure and zinc ligation of human recombinant short-form stromelysin by multidimensional heteronuclear NMR

Network synchronization

Evidence linking CD44‐positive cells and gemcitabine resistance in pancreatic cancer cells: need for further substantiation

Mechanism of inhibition of human leukocyte elastase by two cephalosporin derivatives

Substituted 4,6-diaminoquinolines as inhibitors of C5a receptor binding

Leukotrienes as mediators in frog virus 3-induced hepatitis in rats

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