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MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling

Molecular psychiatry, 2018-04, Vol.23 (4), p.1051-1065

2018

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Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities

Molecular psychiatry, 2015-06, Vol.20 (6), p.703-717

2015

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Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder

Molecular psychiatry, 2015-05, Vol.20 (5), p.573-584

2015

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Histone deacetylase 3 as a novel therapeutic target in multiple myeloma

Leukemia, 2014-03, Vol.28 (3), p.680-689

2014

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Cis-acting regulation of brain-specific ANK3 gene expression by a genetic variant associated with bipolar disorder

Molecular psychiatry, 2013-08, Vol.18 (8), p.922-929

2013

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Functional analysis of rare variants found in schizophrenia implicates a critical role for GIT1-PAK3 signaling in neuroplasticity

Molecular psychiatry, 2017-03, Vol.22 (3), p.417-429

2017

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Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers

Chemical science (Cambridge), 2015-01, Vol.6 (1), p.804-815

2015

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Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

Science (American Association for the Advancement of Science), 1999-10, Vol.286 (5441), p.971-974

1999

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Noncoding RNAs connect genetic risk factors to the neurodevelopmental basis of bipolar disorder

Molecular psychiatry, 2015-05, Vol.20 (5), p.548-548

2015

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Epigenetic mechanisms in mood disorders: Targeting neuroplasticity

Neuroscience, 2014-04, Vol.264, p.112-130

2014

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Domain-Selective Small-Molecule Inhibitor of Histone Deacetylase 6 (HDAC6)-Mediated Tubulin Deacetylation

Proceedings of the National Academy of Sciences - PNAS, 2003-04, Vol.100 (8), p.4389-4394

2003

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Human cerebral organoids reveal deficits in neurogenesis and neuronal migration in MeCP2-deficient neural progenitors

Molecular psychiatry, 2018-04, Vol.23 (4), p.791-791

2018

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Label-free, live optical imaging of reprogrammed bipolar disorder patient-derived cells reveals a functional correlate of lithium responsiveness

Translational psychiatry, 2014-08, Vol.4 (8), p.e428-e428

2014

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The principle of complementarity: chemical versus biological space

Current opinion in chemical biology, 2005-06, Vol.9 (3), p.296-303

Haggarty, Stephen J

2005

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Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips

Proceedings of the National Academy of Sciences - PNAS, 2004-11, Vol.101 (47), p.16594-16599

2004

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Chemical Genomic Profiling of Biological Networks Using Graph Theory and Combinations of Small Molecule Perturbations

Journal of the American Chemical Society, 2003-09, Vol.125 (35), p.10543-10545

2003

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High-throughput assay for G2 checkpoint inhibitors and identification of the structurally novel compound isogranulatimide

Cancer research (Chicago, Ill.), 1998-12, Vol.58 (24), p.5701-5706

1998

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PET Imaging Demonstrates Histone Deacetylase Target Engagement and Clarifies Brain Penetrance of Known and Novel Small Molecule Inhibitors in Rat

ACS chemical neuroscience, 2014-10, Vol.5 (10), p.1055-1062

2014

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Insights into neuroepigenetics through human histone deacetylase PET imaging

Science translational medicine, 2016-08, Vol.8 (351), p.351ra106

2016

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Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

Cell, 2009-03, Vol.136 (6), p.1017-1031

2009

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Mapping chemical space using molecular descriptors and chemical genetics: deacetylase inhibitors

Combinatorial chemistry & high throughput screening, 2004-11, Vol.7 (7), p.669

2004

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EPIGENETIC MECHANISMS IN MOOD DISORDERS: TARGETING NEUROPLASTICITY: Epigenetics in Brain Function

Neuroscience, 2014, Vol.264, p.112-130

2014

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Will cell alliance breed bureaucracy and leave contributors out?

Nature (London), 2000-02, Vol.403 (6770), p.591-591

2000

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Multidimensional Chemical Genetic Analysis of Diversity-Oriented Synthesis-Derived Deacetylase Inhibitors Using Cell-Based Assays

Chemistry & biology, 2003-05, Vol.10 (5), p.383-396

2003

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MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling

Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities

Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder

Histone deacetylase 3 as a novel therapeutic target in multiple myeloma

Cis-acting regulation of brain-specific ANK3 gene expression by a genetic variant associated with bipolar disorder

Functional analysis of rare variants found in schizophrenia implicates a critical role for GIT1-PAK3 signaling in neuroplasticity

Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers

Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

Noncoding RNAs connect genetic risk factors to the neurodevelopmental basis of bipolar disorder

Epigenetic mechanisms in mood disorders: Targeting neuroplasticity

Domain-Selective Small-Molecule Inhibitor of Histone Deacetylase 6 (HDAC6)-Mediated Tubulin Deacetylation

Human cerebral organoids reveal deficits in neurogenesis and neuronal migration in MeCP2-deficient neural progenitors

Label-free, live optical imaging of reprogrammed bipolar disorder patient-derived cells reveals a functional correlate of lithium responsiveness

The principle of complementarity: chemical versus biological space

Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips

Chemical Genomic Profiling of Biological Networks Using Graph Theory and Combinations of Small Molecule Perturbations

High-throughput assay for G2 checkpoint inhibitors and identification of the structurally novel compound isogranulatimide

PET Imaging Demonstrates Histone Deacetylase Target Engagement and Clarifies Brain Penetrance of Known and Novel Small Molecule Inhibitors in Rat

Insights into neuroepigenetics through human histone deacetylase PET imaging

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

A polygenic burden of rare disruptive mutations in schizophrenia

Mapping chemical space using molecular descriptors and chemical genetics: deacetylase inhibitors

EPIGENETIC MECHANISMS IN MOOD DISORDERS: TARGETING NEUROPLASTICITY: Epigenetics in Brain Function

Will cell alliance breed bureaucracy and leave contributors out?

Multidimensional Chemical Genetic Analysis of Diversity-Oriented Synthesis-Derived Deacetylase Inhibitors Using Cell-Based Assays

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