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Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential

Biochimica et biophysica acta, 2009-10, Vol.1790 (10), p.1149-1160

2009

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Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function

Annual review of nutrition, 2013-01, Vol.33 (1), p.45-70

2013

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Strategies to protect against age-related mitochondrial decay: Do natural products and their derivatives help?

Free radical biology & medicine, 2022-01, Vol.178, p.330-346

2022

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Selective Fluorescent Imaging of Superoxide in vivo Using Ethidium-Based Probes

Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (41), p.15038-15043

2006

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Supercomplex Organization of the Electron Transfer System in Marine Bivalves, a Model of Extreme Longevity

The journals of gerontology. Series A, Biological sciences and medical sciences, 2022-02, Vol.77 (2), p.283-290

2022

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Age-related decline in mitochondrial bioenergetics: Does supercomplex destabilization determine lower oxidative capacity and higher superoxide production?

Seminars in cell & developmental biology, 2012-09, Vol.23 (7), p.758-767

2012

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Divergences in the Control of Mitochondrial Respiration Are Associated With Life-Span Variation in Marine Bivalves

The journals of gerontology. Series A, Biological sciences and medical sciences, 2021-05, Vol.76 (5), p.796-804

2021

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Multivitamin/Multimineral Supplementation Prevents or Reverses Decline in Vitamin Biomarkers and Cellular Energy Metabolism in Healthy Older Men: A Randomized, Double-Blind, Placebo-Controlled Study

Nutrients, 2023-06, Vol.15 (12), p.2691

2023

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Decline in Transcriptional Activity of Nrf2 Causes Age-Related Loss of Glutathione Synthesis, Which Is Reversible with Lipoic Acid

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (10), p.3381-3386

2004

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Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a

Free radical biology & medicine, 2015-12, Vol.89, p.1184-1191

2015

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α-Lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (10), p.4077-4082

2007

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Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response

Biochimica et biophysica acta, 2012-06, Vol.1823 (6), p.1102-1109

2012

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Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion

Archives of biochemistry and biophysics, 2009-05, Vol.485 (1), p.63-71

2009

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Mitochondrial Traits Previously Associated With Species Maximum Lifespan Do Not Correlate With Longevity Across Populations of the Bivalve Arctica islandica

Frontiers in physiology, 2019-07, Vol.10, p.946-946

2019

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Supercomplexes of the mitochondrial electron transport chain decline in the aging rat heart

Archives of biochemistry and biophysics, 2009-10, Vol.490 (1), p.30-35

2009

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A Randomized Controlled Trial of Long-Term (R)-α-Lipoic Acid Supplementation Promotes Weight Loss in Overweight or Obese Adults without Altering Baseline Elevated Plasma Triglyceride Concentrations

The Journal of nutrition, 2020-09, Vol.150 (9), p.2336-2345

2020

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Is α‐lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity

IUBMB life, 2008-06, Vol.60 (6), p.362-367

2008

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Age‐associated increases in oxidative stress and antioxidant enzyme activities in cardiac interfibrillar mitochondria: implications for the mitochondrial theory of aging

The FASEB journal, 2005-03, Vol.19 (3), p.1-21

2005

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Biomechanical demands of exercises commonly performed by older adults in falls prevention programs

Clinical biomechanics (Bristol), 2023-01, Vol.101, p.105863, Article 105863

2023

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Age-related loss of mitochondrial glutathione exacerbates menadione-induced inhibition of Complex I

Redox biology, 2019-04, Vol.22, p.101155, Article 101155

2019

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Memory Loss in Old Rats is Associated with Brain Mitochondrial Decay and RNA/DNA Oxidation: Partial Reversal by Feeding Acetyl-L-Carnitine and/or R-α-Lipoic Acid

Proceedings of the National Academy of Sciences - PNAS, 2002-02, Vol.99 (4), p.2356-2361

2002

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Glutathione Metabolism during Aging and in Alzheimer Disease

Annals of the New York Academy of Sciences, 2004-06, Vol.1019 (1), p.346-349

2004

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Identification of age‐specific Nrf2 binding to a novel antioxidant response element locus in the Gclc promoter: a compensatory means for the loss of glutathione synthetic capacity in the aging rat liver?

Aging cell, 2012-04, Vol.11 (2), p.297-304

2012

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Nutritional strategies for healthy cardiovascular aging: Focus on micronutrients

Pharmacological research, 2007-03, Vol.55 (3), p.199-206

2007

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Feeding Acetyl-L-Carnitine and Lipoic Acid to Old Rats Significantly Improves Metabolic Function while Decreasing Oxidative Stress

Proceedings of the National Academy of Sciences - PNAS, 2002-02, Vol.99 (4), p.1870-1875

2002

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Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential

Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function

Strategies to protect against age-related mitochondrial decay: Do natural products and their derivatives help?

Selective Fluorescent Imaging of Superoxide in vivo Using Ethidium-Based Probes

Supercomplex Organization of the Electron Transfer System in Marine Bivalves, a Model of Extreme Longevity

Age-related decline in mitochondrial bioenergetics: Does supercomplex destabilization determine lower oxidative capacity and higher superoxide production?

Divergences in the Control of Mitochondrial Respiration Are Associated With Life-Span Variation in Marine Bivalves

Multivitamin/Multimineral Supplementation Prevents or Reverses Decline in Vitamin Biomarkers and Cellular Energy Metabolism in Healthy Older Men: A Randomized, Double-Blind, Placebo-Controlled Study

Decline in Transcriptional Activity of Nrf2 Causes Age-Related Loss of Glutathione Synthesis, Which Is Reversible with Lipoic Acid

Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a

α-Lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway

Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response

Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion

Mitochondrial Traits Previously Associated With Species Maximum Lifespan Do Not Correlate With Longevity Across Populations of the Bivalve Arctica islandica

Supercomplexes of the mitochondrial electron transport chain decline in the aging rat heart

A Randomized Controlled Trial of Long-Term (R)-α-Lipoic Acid Supplementation Promotes Weight Loss in Overweight or Obese Adults without Altering Baseline Elevated Plasma Triglyceride Concentrations

Is α‐lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity

Age‐associated increases in oxidative stress and antioxidant enzyme activities in cardiac interfibrillar mitochondria: implications for the mitochondrial theory of aging

Biomechanical demands of exercises commonly performed by older adults in falls prevention programs

Age-related loss of mitochondrial glutathione exacerbates menadione-induced inhibition of Complex I

Memory Loss in Old Rats is Associated with Brain Mitochondrial Decay and RNA/DNA Oxidation: Partial Reversal by Feeding Acetyl-L-Carnitine and/or R-α-Lipoic Acid

Glutathione Metabolism during Aging and in Alzheimer Disease

Identification of age‐specific Nrf2 binding to a novel antioxidant response element locus in the Gclc promoter: a compensatory means for the loss of glutathione synthetic capacity in the aging rat liver?

Nutritional strategies for healthy cardiovascular aging: Focus on micronutrients

Feeding Acetyl-L-Carnitine and Lipoic Acid to Old Rats Significantly Improves Metabolic Function while Decreasing Oxidative Stress

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