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The expanding role of prodrugs in contemporary drug design and development

Nature reviews. Drug discovery, 2018-08, Vol.17 (8), p.559-587

2018

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Advanced Formulations/Drug Delivery Systems for Subcutaneous Delivery of Protein-Based Biotherapeutics

Journal of pharmaceutical sciences, 2022-11, Vol.111 (11), p.2968-2982

2022

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Applications of Machine Learning in Solid Oral Dosage Form Development

Journal of pharmaceutical sciences, 2021-09, Vol.110 (9), p.3150-3165

2021

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Machine Learning Attempts for Predicting Human Subcutaneous Bioavailability of Monoclonal Antibodies

Pharmaceutical research, 2021-03, Vol.38 (3), p.451-460

2021

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Development of an In Vitro System To Emulate an In Vivo Subcutaneous Environment: Small Molecule Drug Assessment

Molecular pharmaceutics, 2022-11, Vol.19 (11), p.4017-4025

2022

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Simulating particle movement inside subcutaneous injection site simulator (SCISSOR) using Monte-Carlo method

International journal of pharmaceutics, 2021-08, Vol.605, p.120824-120824, Article 120824

2021

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Development of Drug Release Model for Suspensions in ESCAR (Emulator of SubCutaneous Absorption and Release)

The AAPS journal, 2023-03, Vol.25 (3), p.29-29, Article 29

2023

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Preparation of lapatinib ditosylate solid dispersions using solvent rotary evaporation and hot melt extrusion for solubility and dissolution enhancement

International journal of pharmaceutics, 2018-12, Vol.552 (1-2), p.154-163

2018

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Particle Size Limits to Pass the Acceptance Value (AV)-Based USP Content Uniformity Test for Tablets

Journal of pharmaceutical sciences, 2021-10, Vol.110 (10), p.3527-3534

2021

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Development of a drying method for proteins based on protein-hyaluronic acid precipitation

International journal of pharmaceutics, 2024-04, Vol.654, p.123940-123940, Article 123940

2024

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Biorelevant Dissolution Method Considerations for the Appropriate Evaluation of Amorphous Solid Dispersions: are Two Stages Necessary?

Journal of pharmaceutical sciences, 2023-04, Vol.112 (4), p.1089-1107

2023

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Application of a UV-vis spectrometer to investigate the effect of dissolution media on the diffusivity of small molecules and proteins

Journal of pharmaceutical sciences, 2024-09

2024

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Investigating the Influence of Tablet Location Inside Dissolution Test Apparatus on Polymer Erosion and Drug Release of a Surface-Erodible Sustained-Release Tablet Using Computational Simulation Methods

AAPS PharmSciTech, 2021-03, Vol.22 (3), p.99, Article 99

2021

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Molecular Dynamics Simulation of an Iron(III) Binding Site on the Fc Domain of IgG1 Relevant for Visible Light-Induced Protein Fragmentation

Molecular pharmaceutics, 2024-02, Vol.21 (2), p.501-512

2024

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Initial Drug Dissolution from Amorphous Solid Dispersions Controlled by Polymer Dissolution and Drug-Polymer Interaction

Pharmaceutical research, 2016-10, Vol.33 (10), p.2445-2458

2016

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Investigating protein diffusivities in diluted hyaluronic acid solutions using dynamic light scattering

Analytical methods, 2022-01, Vol.14 (3), p.241-249

2022

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Enhanced Dissolution of Amphotericin B through Development of Amorphous Solid Dispersions Containing Polymer and Surfactants

Journal of pharmaceutical sciences, 2024-08, Vol.113 (8), p.2454-2463

2024

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Drug–Polymer–Water Interaction and Its Implication for the Dissolution Performance of Amorphous Solid Dispersions

Molecular pharmaceutics, 2015-02, Vol.12 (2), p.576-589

2015

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Enhancing Intestinal Absorption of a Model Macromolecule via the Paracellular Pathway using E-Cadherin Peptides

Journal of pharmaceutical sciences, 2021-05, Vol.110 (5), p.2139-2148

2021

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Do Macrocyclic Peptide Drugs Interact with Bile Salts under Simulated Gastrointestinal Conditions?

Molecular pharmaceutics, 2021-08, Vol.18 (8), p.3086-3098

2021

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The application of machine learning algorithms in understanding the effect of core/shell technique on improving powder compactability

International journal of pharmaceutics, 2019-01, Vol.555, p.368-379

2019

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Moisture-Induced Amorphous Phase Separation of Amorphous Solid Dispersions: Molecular Mechanism, Microstructure, and Its Impact on Dissolution Performance

Journal of pharmaceutical sciences, 2018-01, Vol.107 (1), p.317-326

2018

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Application of Lipid-Based Formulations in Drug Discovery

Journal of medicinal chemistry, 2012-09, Vol.55 (18), p.7945-7956

2012

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Lipophilic salts of poorly soluble compounds to enable high-dose lipidic SEDDS formulations in drug discovery

European journal of pharmaceutics and biopharmaceutics, 2017-08, Vol.117, p.212-223

2017

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The expanding role of prodrugs in contemporary drug design and development

Advanced Formulations/Drug Delivery Systems for Subcutaneous Delivery of Protein-Based Biotherapeutics

Applications of Machine Learning in Solid Oral Dosage Form Development

Machine Learning Attempts for Predicting Human Subcutaneous Bioavailability of Monoclonal Antibodies

Development of an In Vitro System To Emulate an In Vivo Subcutaneous Environment: Small Molecule Drug Assessment

Simulating particle movement inside subcutaneous injection site simulator (SCISSOR) using Monte-Carlo method

Development of Drug Release Model for Suspensions in ESCAR (Emulator of SubCutaneous Absorption and Release)

Preparation of lapatinib ditosylate solid dispersions using solvent rotary evaporation and hot melt extrusion for solubility and dissolution enhancement

Particle Size Limits to Pass the Acceptance Value (AV)-Based USP Content Uniformity Test for Tablets

Development of a drying method for proteins based on protein-hyaluronic acid precipitation

Biorelevant Dissolution Method Considerations for the Appropriate Evaluation of Amorphous Solid Dispersions: are Two Stages Necessary?

Application of a UV-vis spectrometer to investigate the effect of dissolution media on the diffusivity of small molecules and proteins

Investigating the Influence of Tablet Location Inside Dissolution Test Apparatus on Polymer Erosion and Drug Release of a Surface-Erodible Sustained-Release Tablet Using Computational Simulation Methods

Molecular Dynamics Simulation of an Iron(III) Binding Site on the Fc Domain of IgG1 Relevant for Visible Light-Induced Protein Fragmentation

Initial Drug Dissolution from Amorphous Solid Dispersions Controlled by Polymer Dissolution and Drug-Polymer Interaction

Investigating protein diffusivities in diluted hyaluronic acid solutions using dynamic light scattering

Enhanced Dissolution of Amphotericin B through Development of Amorphous Solid Dispersions Containing Polymer and Surfactants

Drug–Polymer–Water Interaction and Its Implication for the Dissolution Performance of Amorphous Solid Dispersions

Enhancing Intestinal Absorption of a Model Macromolecule via the Paracellular Pathway using E-Cadherin Peptides

Do Macrocyclic Peptide Drugs Interact with Bile Salts under Simulated Gastrointestinal Conditions?

The application of machine learning algorithms in understanding the effect of core/shell technique on improving powder compactability

Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal

Moisture-Induced Amorphous Phase Separation of Amorphous Solid Dispersions: Molecular Mechanism, Microstructure, and Its Impact on Dissolution Performance

Application of Lipid-Based Formulations in Drug Discovery

Lipophilic salts of poorly soluble compounds to enable high-dose lipidic SEDDS formulations in drug discovery

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